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Dihydropyrimidinase Proteins (DPYS)

Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Additionally we are shipping DPYS Antibodies (105) and DPYS Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DPYS 1807 Q14117
DPYS 64705 Q9EQF5
DPYS 65135 Q63150
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Top DPYS Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Baculovirus infected Insect Cells Human His tag,GST tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,477.83
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

DPYS Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Dihydropyrimidinase (DPYS) Interaction Partners

Human Dihydropyrimidinase (DPYS) interaction partners

  1. Two unrelated pediatric DPYS deficiency cases are being described as compound heterozygotes for a novel intronic mutation c.1443+5G>A in intron 8 and a previously described missense mutation c.1001A>G (p.Q334R) in exon 6.

  2. Stepwise Cox (show COX8A Proteins) regression modelling suggested that the methylation of genes HSPB1 (show HSPB1 Proteins), CCND2 (show CCND2 Proteins) and DPYS contributed objective prognostic information to Gleason score and PSA (show PLAG1 Proteins) with respect to prostate cancer-related death.

  3. The p.S379R and p.L7V mutations were likely to cause structural destabilization and protein misfolding. Four mutations were identified in multiple unrelated DHP (show DPYD Proteins) patients, indicating that DHP (show DPYD Proteins) deficiency may be more common than anticipated.

  4. Results indicate that missense and nonsense variants in DPYS are infrequent, however, the development of serious primarily gastrointestinal toxicity could be influenced by non-coding DPYS sequence variants c.-1T>C and IVS1-58T>C.

  5. clinical, biochemical & genetic findings of two newly identified patients with a complete DHP (show DPYD Proteins) deficiency; both patients were compound heterozygous for the missense mutation 1078T>C (W360R) in exon 6 and a novel missense mutation 1235G>T (R412M) in exon 7

  6. data presented in this study offers evidence for the possible genetic regulation of the DPYS gene and its possible influence on uracil catabolic pathway

DPYS Protein Profile

Protein Summary

Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.

Gene names and symbols associated with Dihydropyrimidinase Proteins (DPYS)

  • dihydropyrimidinase-like (LOC100856067)
  • dihydropyrimidinase (Jann_1488)
  • dihydropyrimidinase (Bxe_C0732)
  • dihydropyrimidinase (h16_A3075)
  • dihydropyrimidinase (Veis_0725)
  • dihydropyrimidinase (AZC_1966)
  • dihydropyrimidinase (M446_2543)
  • dihydropyrimidinase (RSKD131_3628)
  • dihydropyrimidinase (Vapar_5601)
  • dihydropyrimidinase (Rleg_5687)
  • dihydropyrimidinase (ARALYDRAFT_488062)
  • dihydropyrimidinase (EIO_3239)
  • dihydropyrimidinase (blr3333)
  • dihydropyrimidinase (hydA)
  • dihydropyrimidinase (BAV0676)
  • dihydropyrimidinase (hyuA)
  • dihydropyrimidinase (CtCNB1_2936)
  • dihydropyrimidinase (dpyS)
  • dihydropyrimidinase (Pat9b_1914)
  • dihydropyrimidinase (dpys)
  • dihydropyrimidinase (DPYS)
  • dihydropyrimidinase (Dpys)
  • 1200017I10Rik protein
  • 1300004I01Rik protein
  • DHP protein
  • DHPase protein

Protein level used designations for Dihydropyrimidinase Proteins (DPYS)

dihydropyrimidinase , dihydropyrimidine amidohydrolase , hydantoinase , DHP , DHPase

GENE ID SPECIES
100856067 Canis lupus familiaris
3933935 Jannaschia sp. CCS1
4010267 Burkholderia xenovorans LB400
4249970 Ralstonia eutropha H16
4690821 Verminephrobacter eiseniae EF01-2
5690979 Azorhizobium caulinodans ORS 571
6132533 Methylobacterium sp. 4-46
7353624 Rhodobacter sphaeroides KD131
7975213 Variovorax paradoxus S110
8016650 Rhizobium leguminosarum bv. trifolii WSM1325
9307588 Arabidopsis lyrata subsp. lyrata
9886600 Ketogulonicigenium vulgare Y25
1050490 Bradyrhizobium diazoefficiens USDA 110
4196355 Roseobacter denitrificans OCh 114
6264902 Bordetella avium 197N
6453799 Cupriavidus taiwanensis LMG 19424
8564745 Comamonas testosteroni CNB-2
8791932 Azospirillum sp. B510
10069347 Pantoea sp. At-9b
100144569 Danio rerio
495311 Xenopus laevis
420266 Gallus gallus
1807 Homo sapiens
475067 Canis lupus familiaris
509241 Bos taurus
64705 Mus musculus
65135 Rattus norvegicus
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