You are viewing an incomplete version of our website. Please click to reload the website as full version.

Dihydropyrimidinase-Like 5 Proteins (DPYSL5)

DPYSL5 encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Additionally we are shipping Dihydropyrimidinase-Like 5 Antibodies (43) and Dihydropyrimidinase-Like 5 Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DPYSL5 56896 Q9BPU6
DPYSL5 65254 Q9EQF6
DPYSL5 65208 Q9JHU0
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Dihydropyrimidinase-Like 5 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,556.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

DPYSL5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Dihydropyrimidinase-Like 5 (DPYSL5) Interaction Partners

Human Dihydropyrimidinase-Like 5 (DPYSL5) interaction partners

  1. Our findings suggest that CRMP5 serves as a major mediator of Notch (show NOTCH1 Proteins) signaling and Akt (show AKT1 Proteins) activation by controlling the degradation of the Notch (show NOTCH1 Proteins) receptor, with implications for defining a biomarker signature in glioblastoma

  2. present study suggested that CRAM (show CCRL2 Proteins) could be a clinical prognostic marker for patients with cervical cancer

  3. study elucidates a novel regulatory mechanism that utilizes CRMP5-induced mitophagy to orchestrate proper dendrite outgrowth and neuronal function.

  4. identified residues that are crucial for determining the preference for hetero-oligomer or homo-oligomer formation. In spite of being the CRMP family member most closely related to dihydropyrimidinase (show DPYS Proteins), CRMP-5 does not have amidohydrolase activity.

  5. New CRMP5 isoform present in the nucleus is associated with Glioma.

  6. CRMP-5-IgG defines a paraneoplastic ophthalmological entity of combined optic neuritis and retinitis with vitreous inflammatory cells.

  7. CRMP-5 autoimmune myelopathy and occult neoplasia are important considerations in patients with insidiously progressive myelopathy, especially with known cancer risk.

  8. We describe a patient with optic neuropathy and vitritis as the only clinical manifestations of paraneoplastic optic neuropathy secondary to lung cancer marked by an extremely high titer of CRMP-5 antibody.

  9. findings point at CRMP5 as a novel marker for distinguishing between highly aggressive neuroendocrine carcinoma and the other lung cancers.

  10. patients with CV2 (show BMPER Proteins)/CRMP5-Ab and thymoma developed myasthenic syndrome more frequently

Mouse (Murine) Dihydropyrimidinase-Like 5 (DPYSL5) interaction partners

  1. study elucidates a novel regulatory mechanism that utilizes CRMP5-induced mitophagy to orchestrate proper dendrite outgrowth and neuronal function.

  2. CRMP5-deficient mice show abnormal Schwann process extension resulting in abnormal cell-axon segregation, indicating that CRMP5 is involved in the morphologic adaptation of Schwann cells to surround axons.

  3. These findings provide the first evidence that CRMP5 is involved in the generation and survival of newly generated neurons in areas of the adult brain with a high level of activity-dependent neuronal plasticity.

  4. Data show that CRMP5 is involved in the development, maintenance and synaptic plasticity of Purkinje cells.

  5. The CRMP5 binding to tubulin (show TUBB Proteins) modulates CRMP2 (show DPYSL2 Proteins) regulation of neurite outgrowth and neuronal polarity during brain development.

  6. CRAM regulates filopodial dynamics and growth cone development, thereby restricting the response of growth cone to repulsive guidance cues

  7. In the olfactory bulb, CRMP1 (show CRMP1 Proteins), CRMP2 (show DPYSL2 Proteins) and CRMP5 are abundant in neuronal progenitors of the subependymal layer and in differentiating interneurons.

  8. Our results are therefore consistent with a role for CRMP5 in neuronal process extension.We conclude that expression of CRMP5 is consistent with a dynamic implicit role in forebrain development.

  9. Hypoxia-ischemia (HI)induces dephosphorylation of CRMPs (CRMP1 (show CRMP1 Proteins), 2, and 5) in neonatal brain. Hypophosphorylated CRMPs might be implicated in the pathogenesis of HI-related neurological disorders.

Dihydropyrimidinase-Like 5 (DPYSL5) Protein Profile

Protein Summary

This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with DPYSL5

  • dihydropyrimidinase-like 5 (DPYSL5)
  • Dihydropyrimidinase-related protein 5 (dpyl5)
  • dihydropyrimidinase-like 5a (dpysl5a)
  • dihydropyrimidinase-like 5 (dpysl5)
  • dihydropyrimidinase-like 5 (Dpysl5)
  • CRAM protein
  • CRMP-5 protein
  • CRMP-5a protein
  • Crmp5 protein
  • crmp5.1 protein
  • DPYSL5 protein
  • fc28b06 protein
  • im:7146614 protein
  • Ulip6 protein
  • wu:fc28b06 protein

Protein level used designations for DPYSL5

dihydropyrimidinase-like 5 , dihydropyrimidinase-related protein 5 , Dihydropyrimidinase-related protein 5 , collapsin response mediator protein-5 , dihydropyrimidinase-related protein 5-like , CRMP3-associated molecule , DRP-5 , ULIP-6 , UNC33-like phosphoprotein 6 , collapsin response mediator protein 5

GENE ID SPECIES
483004 Canis lupus familiaris
699648 Macaca mulatta
100126171 Bos taurus
100196759 Salmo salar
100353506 Oryctolagus cuniculus
324416 Danio rerio
100030914 Monodelphis domestica
100071300 Equus caballus
100386950 Callithrix jacchus
100478389 Ailuropoda melanoleuca
100496348 Xenopus (Silurana) tropicalis
100511810 Sus scrofa
100558703 Anolis carolinensis
100598354 Nomascus leucogenys
56896 Homo sapiens
65254 Mus musculus
65208 Rattus norvegicus
Selected quality suppliers for Dihydropyrimidinase-Like 5 Proteins (DPYSL5)
Did you look for something else?