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Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Additionally we are shipping DPYSL3 Proteins (6) and DPYSL3 Kits (5) and many more products for this protein.
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Human Polyclonal DPYSL3 Primary Antibody for IHC, ELISA - ABIN347041
Veyrac, Giannetti, Charrier, Reymond-Marron, Aguera, Rogemond, Honnorat, Jourdan: Expression of collapsin response mediator proteins 1, 2 and 5 is differentially regulated in newly generated and mature neurons of the adult olfactory system. in The European journal of neuroscience 2005
Show all 9 references for ABIN347041
Human Polyclonal DPYSL3 Primary Antibody for WB - ABIN947802
Khazaei, Girouard, Alchini, Ong Tone, Shimada, Bechstedt, Cowan, Guillet, Wiseman, Brouhard, Cloutier, Fournier: Collapsin response mediator protein 4 regulates growth cone dynamics through the actin and microtubule cytoskeleton. in The Journal of biological chemistry 2014
Chicken Polyclonal DPYSL3 Primary Antibody for IHC, WB - ABIN2784712
Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006
DPYSL3 expression levels inversely correlated with those of VEGF (show VEGFA Antibodies) and FAK (show PTK2 Antibodies). Down-regulation of DPYSL3 expression in HCC (show FAM126A Antibodies) tissues may serve as a predictive biomarker for HCC (show FAM126A Antibodies) after curative resection.
Expression status of DPYSL3 in gastric cancer tissues may represent a promising biomarker for the malignant behavior of GC.
DPYSL3 as pancreatic ductal adenocarcinoma-associated (show EPCAM Antibodies) molecule that regulates cell adhesion and migration by stabilization of focal adhesion complex
structures provide further insight into the effects of medically relevant mutations of the DPYSL-3 gene encoding CRMP-4 and the putative enzymatic activities of CRMPs
High collapsin response mediator protein 4 expression is associated with liver metastasis in pancreatic cancer.
Downregulation of MYCN (show MYCN Antibodies) by small interfering RNA (siRNA) increased DPYSL3 levels, while upregulation of MYCN (show MYCN Antibodies) in non-MYCN (show MYCN Antibodies) NB cells decreased DPYSL3 levels.
study found the association between the rs147541241 variant and amyotrophic lateral scerosis was limited to the French population
Ulip1 was downregulated and HIF1a (show HIF1A Antibodies) was upregulated in hypoxic neuroblastoma (show ARHGEF16 Antibodies) cells.
CRMP4 is a key physiological substrate of GSK3 (show GSK3b Antibodies) in regulating chromosomal alignment and mitotic progression through its effect on spindle microtubules
Data show that two genes, LTB4DH (show PTGR1 Antibodies) and DPYSL3, were confirmed to be candidate genes for the predictor of a good immune response.
our data suggest that disruption of CRMP4 produces a temporary alteration in the thickness of the external of the olfactory bulb, which is constituted mainly of mitral cell apical dendrites, through the enhanced growth of these dendrites
These results suggest that deletion of CRMP4 is a unique therapeutic strategy that overcomes two obstacles to CNS repair after SCI.
CRMP4 inhibits prostate cancer cells growth in the nude mouse bone microenvironment.
This study identified a dual role for CRMP4 in regulating the actin and microtubule growth cone cytoskeleton.
In the human ortholog of Dpysl3, the association between the rs147541241 variant and amyotrophic lateral sclerosis was limited to the French population.
CRMP4 regulates the number of tyrosine hydroxylase (show TH Antibodies) immunoreactive neurons in the female anteroventral periventricular nucleus.
Results suggest that CRMP4 suppresses apical dendrite bifurcation of CA1 (show CA1 Antibodies) pyramidal neurons in the mouse hippocampus and that this is partly dependent on Sema3A (show SEMA3A Antibodies) signaling.
MAG-mediated axon protection against VNC is suppressed in CRMP4-/- DRG neurons.
Hypoxia-ischemia (HI)induces dephosphorylation of CRMPs (CRMP1 (show CRMP1 Antibodies), 2, and 5) in neonatal brain. Hypophosphorylated CRMPs might be implicated in the pathogenesis of HI-related neurological disorders.
phosphorylation of Dpysl2 (show DPYSL2 Antibodies) and Dpysl3 by Cyclin-dependent kinase 5 (show CDK5 Antibodies) and dual-specificity tyrosine-phosphorylated and regulated kinase 2 is required for correct positioning of CaP motor neurons in the zebrafish spinal cord
These results suggest that the phosphorylation of Dpysl2 (show DPYSL2 Antibodies) and Dpysl3 by Cdk5 (show CDK5 Antibodies) and DYRK2 (show DYRK2 Antibodies) is required for the proper positioning of Rohon-Beard neurons and neural crest cells during neurulation in zebrafish embryos.
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).
collapsin response mediator protein-4A
, collapsin response mediator protein-4B
, dihydropyrimidinase-related protein 3
, dihydropyrimidinase-like 3
, Dihydropyrimidinase-related protein 3
, hypothetical protein LOC494650
, Collapsin response mediator protein 4
, collapsin response mediator protein 4 long-like
, collapsin response mediator protein 4 long
, unc-33-like phosphoprotein 1
, collapsin response mediator protein 4
, TOAD-64/Ulip/CRMP protein 4b
, dihydropyrimidinase-related protein 3-A
, neural-specific protein 1