DnaJ (Hsp40) Homolog, Subfamily B, Member 12 Proteins (DNAJB12)

DNAJB12 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. Additionally we are shipping DNAJB12 Antibodies (54) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DNAJB12 54788 Q9NXW2
DNAJB12 56709 Q9QYI4
Rat DNAJB12 DNAJB12 294513  
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Top DNAJB12 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,041.49
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
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HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$333.33
Details

DNAJB12 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for DnaJ (Hsp40) Homolog, Subfamily B, Member 12 (DNAJB12) Interaction Partners

Human DnaJ (Hsp40) Homolog, Subfamily B, Member 12 (DNAJB12) interaction partners

  1. ER-located J-protein chaperones were identified as key regulators for the iogenesis and physiological function of ERG (show ERG Proteins) K+ channels. They regulate two distinct aspects of K+ channel (show KCNC4 Proteins) biogenesis, the stabilization and assembly of channel subunits.

  2. Data suggest that endoplasmic reticulum (ER) stress-induced apoptosis in hepatoma cells is regulated by highly labile and ER-associated BCL-2 (show BCL2 Proteins) family member BOK (show BOK Proteins), which is controlled at level of protein stability by ER-associated degradation components; DNAJB12 is required in hepatoma cells to maintain BOK (show BOK Proteins) at low levels and suppress ER stress. (DNAJB12 = DnaJ (Hsp40 (show DNAJB1 Proteins)) homolog (show DNAJB4 Proteins), subfamily B, member 12)

  3. Over-expression of DNAJB12 or DNAJB14 (show DNAJB14 Proteins) causes the formation of elaborate membranous structures within cell nuclei, designated DJANGOS for DNAJ (show DNAJB6 Proteins)-associated nuclear globular structures.

  4. JB12 cooperates with cytosolic Hsc70 (show HSPA8 Proteins) and the ubiquitin ligase RMA1 to target CFTR (show CFTR Proteins) and CFTRDeltaF508 for degradation.

  5. DNAJB12 is a novel mammalian ER-localized J-protein that plays a vital role in the quality control of membrane proteins

DNAJB12 Protein Profile

Protein Summary

DNAJB12 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus\; a glycine/phenylalanine (G/F)-rich region\; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000

Gene names and symbols associated with DNAJB12

  • DnaJ (Hsp40) homolog, subfamily B, member 12a (dnajb12a)
  • DnaJ (Hsp40) homolog, subfamily B, member 12 (DNAJB12)
  • DnaJ (Hsp40) homolog, subfamily B, member 12 (dnajb12)
  • DnaJ (Hsp40) homolog, subfamily B, member 12 (LOC100226454)
  • DnaJ (Hsp40) homolog, subfamily B, member 12 (Dnajb12)
  • Dj10 protein
  • DNAJB12 protein
  • mDj10 protein
  • MGC82876 protein
  • wu:fc16f06 protein
  • wu:fi38b10 protein

Protein level used designations for DNAJB12

DnaJ (Hsp40) homolog, subfamily B, member 12 , dnaJ homolog subfamily B member 12 , dnaJ homolog subfamily B member 12-like , DnaJ homolog 10

GENE ID SPECIES
324005 Danio rerio
423707 Gallus gallus
444375 Xenopus laevis
450887 Pan troglodytes
489039 Canis lupus familiaris
548745 Xenopus (Silurana) tropicalis
100156234 Sus scrofa
100397318 Callithrix jacchus
100442940 Pongo abelii
100226454 Taeniopygia guttata
54788 Homo sapiens
56709 Mus musculus
294513 Rattus norvegicus
533603 Bos taurus
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