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anti-Docking Protein 3 (DOK3) Antibodies

DOK proteins are enzymatically inert adaptor or scaffolding proteins. Additionally we are shipping DOK3 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DOK3 79930 Q7L591
DOK3 27261 Q9QZK7
DOK3 306760 B2RYG7
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Top anti-DOK3 Antibodies at antibodies-online.com

Showing 10 out of 94 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin fixed and paraffin embedded human lung tissue reacted with DOK3 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of DOK3 Antibody (C-term) in CEM cell line lysates (35ug/lane). This demonstrates the DOK3 antibody detected the DOK3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB ABIN184642 staining (1µg/ml) of Human PBMC lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HepG2 cells, using DOK3 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB DOK3 Antibody (C-term) (ABIN655979) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Goat Un-conjugated EIA, IHC (p), WB Human Placenta: Formalin-Fixed, Parraffin-Embedded (FFPE) Human Spleen: Formalin-Fixed, Parraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: A431 , 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Spleen: Formalin-Fixed, Parraffin-Embedded (FFPE) Human Placenta: Formalin-Fixed, Parraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details

DOK3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-DOK3 Antibodies

  1. Human Polyclonal DOK3 Primary Antibody for EIA, IHC (p) - ABIN951967 : Berger, Niki, Morotti, Taylor, Socci, Viale, Brennan, Szoke, Motoi, Rothman, Teruya-Feldstein, Gerald, Ladanyi, Pandolfi: Identification of DOK genes as lung tumor suppressors. in Nature genetics 2010 (PubMed)
    Show all 5 references for ABIN951967

  2. Cow (Bovine) Polyclonal DOK3 Primary Antibody for WB - ABIN374125 : Heckel, Czupalla, Expirto Santo, Anitei, Arantzazu Sanchez-Fernandez, Mosch, Krause, Hoflack: Src-dependent repression of ARF6 is required to maintain podosome-rich sealing zones in bone-digesting osteoclasts. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)

  3. Human Polyclonal DOK3 Primary Antibody for ELISA, WB - ABIN184642 : Lemay, Davidson, Latour, Veillette: Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling. in Molecular and cellular biology 2000 (PubMed)

More Antibodies against DOK3 Interaction Partners

Human Docking Protein 3 (DOK3) interaction partners

  1. DOK2 and DOK3 expression was significantly reduced in HTLV-1-infected T cells.

  2. The Dok-3/Grb2 (show GRB2 Antibodies) protein signal module attenuates Lyn (show LYN Antibodies) kinase-dependent activation of Syk (show SYK Antibodies) kinase in B cell antigen receptor microclusters

  3. absence of DOK3 increases LPS (show IRF6 Antibodies) signaling, contributing to LPS (show IRF6 Antibodies)-induced tolerance. Thus, DOK3 plays a role in TLR signaling during both naive and endotoxin-induced tolerant conditions

  4. The novel platelet adapter Dok-3 is tyrosine phosphorylated in an Src kinase (show CSK Antibodies)-independent manner downstream of alphaIIbbeta3 in human platelets, leading to an interaction with Grb2 (show GRB2 Antibodies) and SHIP-1 (show INPP5D Antibodies).

  5. findings indicate that Dok-3 sequesters Grb2 (show GRB2 Antibodies) from Shc (show SHC1 Antibodies) and inhibits the Ras-Erk (show EPHB2 Antibodies) pathway downstream of PTKs

Mouse (Murine) Docking Protein 3 (DOK3) interaction partners

  1. we demonstrate that CpG treatment leads to ubiquitin-mediated degradation of DOK3 via interaction with an E3 ligase TNFR (show TNFRSF1A Antibodies)-associated factor 6 (TRAF6 (show TRAF6 Antibodies)).

  2. This study reveals DOK3 as a nonredundant regulator of plasma cell differentiation by up-regulating PD-1 (show PDCD1 Antibodies) ligand expression through the attenuation of calcium signaling.

  3. Data show that docking protein 3 (DOK3) plays a role in TLR3 (show TLR3 Antibodies) signaling by enabling TNFR (show TNFRSF1A Antibodies)-associated factor (TRAF) 3 (show TRAF3 Antibodies)/TANK-binding kinase (TBK) 1 (show TBK1 Antibodies) binding and facilitating TBK1 (show TBK1 Antibodies) and IFN regulatory factor 3 activation and the induction of IFN-beta (show IFNB1 Antibodies) production.

  4. DOK3 physically associated with the ITAM of DAP12 (show TYROBP Antibodies) through its phosphotyrosine-binding domain. In response to LPS (show TLR4 Antibodies), DOK3 was phosphorylated in a DAP12 (show TYROBP Antibodies)- and Src (show SRC Antibodies)-dependent manner, which led to translocation of phosphorylated DOK3 to the plasma membrane.

  5. Triple Dok1 (show DOK1 Antibodies) Doc2 (show DOC2A Antibodies) Doc3 knockout leads to spontaneous pulmonary inflammation with hallmarks of asthma.

  6. absence of DOK3 increases LPS (show TLR4 Antibodies) signaling, contributing to LPS (show TLR4 Antibodies)-induced tolerance. Thus, DOK3 plays a role in TLR signaling during both naive and endotoxin-induced tolerant conditions

  7. identify a surprising but pivotal role for dynein and the microtubule network alongside Grb2 (show GRB2 Antibodies), Dok-3, and Cbl (show CBL Antibodies) in antigen gathering during B cell activation (show BLNK Antibodies)

  8. Subcellular localization of Grb2 (show GRB2 Antibodies) by the adaptor protein Dok-3 restricts the intensity of Ca2 (show CA2 Antibodies)+ signaling in B cells.

  9. In the absence of Dok-3, the localization of the inhibitory phosphatase SHIP-1 (show INPP5D Antibodies) to the plasma membrane is intact while its phosphorylation is compromised, suggesting that Dok-3 could function to facilitate or sustain the activation of SHIP-1 (show INPP5D Antibodies).

DOK3 Antigen Profile

Protein Summary

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. Plays a role as negative regulator of the mobilization of calcium ions and of calcium signaling.

Gene names and symbols associated with DOK3

  • docking protein 3 (DOK3) antibody
  • docking protein 3 (Dok3) antibody
  • AI450713 antibody
  • DOK3 antibody
  • Dokl antibody

Protein level used designations for DOK3

docking protein 3 , Dok-like protein , downstream of tyrosine kinase 3 , DOK-L , p62(dok)-like protein , p62Dok-like protein , Downstream of tyrosine kinase 3

GENE ID SPECIES
462309 Pan troglodytes
489087 Canis lupus familiaris
514894 Bos taurus
79930 Homo sapiens
27261 Mus musculus
306760 Rattus norvegicus
429960 Gallus gallus
Selected quality suppliers for anti-DOK3 (DOK3) Antibodies
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