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Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. Additionally we are shipping DUSP19 Antibodies (36) and many more products for this protein.
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Human DUSP19 Protein expressed in Escherichia coli (E. coli) - ABIN667987
Cheng, Gao, Jiang, Ma, Ni, Guo, Jin, Cao, Ji, Ying, Xu, Gu, Ma, Xie, Mao: Molecular cloning and characterization of a novel human protein phosphatase, LMW-DSP3. in The international journal of biochemistry & cell biology 2002
Show all 2 references for ABIN667987
the activity of JNK (show MAPK8 Proteins) stimulated by leptin (show LEP Proteins) was suppressed by DUSP19 overexpression.
crystal structure of SKRP1 (C150S) has been determined and refined at 1.26 A resolution (Table I). The structure reveals 142 residues (residues 65-206) of SKRP1 and three ions (two sulfates and one phosphate) at the catalytic site
LMW-DSP3 was expressed in the heart, lung, liver, and pancreas, and the expression level in the pancreas was highest. The LMW-DSP3 gene was located in human chromosome 2q32, and consisted of five exons spanning 21kb of human genomic DNA[LMW-DSP3]
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009
dual specificity phosphatase 19
, dual specificity protein phosphatase 19
, dual specificity protein phosphatase 19-like
, SAPK pathway-regulating phosphatase 1
, dual specificity phosphatase TS-DSP1
, low molecular weight dual specificity phosphatase 3
, protein phosphatase SKRP1
, stress-activated protein kinase pathway-regulating phosphatase 1