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Dual Specificity Phosphatase 22 Proteins (DUSP22)

Activates the Jnk signaling pathway. Additionally we are shipping DUSP22 Antibodies (72) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DUSP22 56940 Q9NRW4
DUSP22 105352 Q99N11
Rat DUSP22 DUSP22 361242  
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Top DUSP22 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,513.50
Details
HOST_Escherichia coli (E. coli) Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$510.36
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

DUSP22 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Dual Specificity Phosphatase 22 (DUSP22) Interaction Partners

Human Dual Specificity Phosphatase 22 (DUSP22) interaction partners

  1. findings suggest that CCR8 (show CCR8 Proteins) expression in ALCL is more closely related to the presence of DUSP22 rearrangements than to cutaneous involvement and that the function of CCR8 (show CCR8 Proteins) may extend beyond its skin-homing properties in this disease

  2. Studies suggest that the presence of dual specificity phosphatase 22 (DUSP22) and p63 (show RPE65 Proteins) tumor suppressor protein (show TP53 Proteins) (TP63 (show TP63 Proteins)) rearrangements might be useful to support a diagnosis of anaplastic lymphoma kinase (ALK)-negative anaplastic large cell lymphoma (ALCL).

  3. Report morphologic features of ALK-negative anaplastic large cell lymphomas with DUSP22 gene rearrangements.

  4. Reduced DUSP22 expression was found in colorectal cancer specimens. Low expression level of DUSP22 in stage IV patients had a poor survival outcome

  5. The structure illuminates the molecular basis for substrate binding and may also facilitate the structure-assisted development of DUSP22 inhibitors.

  6. study identified presence of promoter hypermethylation of the DUSP22 gene in Alzheimer's disease(AD); DUSP22 is a likely candidate gene for involvement in the pathogenesis of AD since it inhibits PKA activity and thereby determines TAU phosphorylation status and CREB (show CREB1 Proteins) signaling

  7. Biallelic rearrangements of DUSP22 is found in CD30 (show TNFRSF8 Proteins)-positive T-cell lymphoproliferative disorders.

  8. Firefighters had a higher prevalence of dual specificity phosphatase 22-promoter hypomethylation in blood DNA (P = 0.03) and the extent of hypomethylation correlated with duration of firefighting service (P = 0.04) but not with age.

  9. Data show that t(6;7)(p25.3;q32.3) was associated with down-regulation of DUSP22 and up-regulation of MIR29 microRNAs on 7q32.3.

  10. a new role for JKAP in the modulation of FAK (show PTK2 Proteins) phosphorylation and cell motility.

Mouse (Murine) Dual Specificity Phosphatase 22 (DUSP22) interaction partners

  1. cloning and characterization of JKAP, a positive regulator of the JNK (show MAPK8 Proteins) pathway

  2. DSP2 acts as a negative regulator of the IL-6 (show IL6 Proteins)/LIF (show LIF Proteins)/STAT3 (show STAT3 Proteins)-mediated signaling pathway.

DUSP22 Protein Profile

Protein Summary

Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N- terminal kinase (SAPK/JNK) (By similarity).

Gene names and symbols associated with DUSP22

  • dual specificity phosphatase 22 (DUSP22)
  • dual specificity phosphatase 22a (dusp22a)
  • dual specificity phosphatase 22 (dusp22)
  • dual specificity phosphatase 22b (dusp22b)
  • dual specificity phosphatase 22 (LOC100227799)
  • dual specificity phosphatase 22 (LOC100353877)
  • dual specificity phosphatase 22 (Dusp22)
  • 1110028K04Rik protein
  • AW212235 protein
  • ch73-170d1.1 protein
  • DUSP22 protein
  • JKAP protein
  • JSP1 protein
  • LMWDSP2 protein
  • MKPX protein
  • VHX protein
  • wu:fa11e09 protein
  • zgc:92816 protein
  • zgc:112536 protein

Protein level used designations for DUSP22

dual specificity phosphatase 22 , dual specificity protein phosphatase 22-A , dual specificity protein phosphatase 22 , dual specificity phosphatase 22 like , dual specificity protein phosphatase 22-B , JNK-stimulating phosphatase 1 , JNK-stimulatory phosphatase-1 , JSP-1 , LMW-DSP2 , MAP kinase phosphatase x , MKP-x , homolog of mouse dual specificity phosphatase LMW-DSP2 , low molecular weight dual specificity phosphatase 2 , mitogen-activated protein kinase phosphatase x

GENE ID SPECIES
420887 Gallus gallus
436787 Danio rerio
496452 Xenopus (Silurana) tropicalis
705824 Macaca mulatta
750495 Pan troglodytes
100002272 Danio rerio
100227799 Taeniopygia guttata
100353877 Oryctolagus cuniculus
56940 Homo sapiens
105352 Mus musculus
361242 Rattus norvegicus
787471 Bos taurus
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