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anti-Dynein, Axonemal, Heavy Chain 5 (Dnah5) Antibodies

Dnah5 encodes a dynein protein, which is part of a microtubule-associated motor protein complex consisting of heavy, light, and intermediate chains.

list all antibodies Gene Name GeneID UniProt
Dnah5 1767 Q8TE73
Dnah5 110082 Q8VHE6
Anti-Rat Dnah5 Dnah5 294854  
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Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Dog Goat Un-conjugated ELISA 100 μL Log in to see 14 Days
$430.99
Details

Dnah5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human


Mouse (Murine)


More Antibodies against Dnah5 Interaction Partners

Human Dynein, Axonemal, Heavy Chain 5 (Dnah5) interaction partners

  1. The mutation of p.Glu2610Gly in DNAH5 is novel.

  2. In chronic obstructive pulmonary disease, total lung capacity was associated with a SNP in DNAH5.

  3. A novel mutation in DNAH5 (c. 8030G>A) is identified in a Han Chinese family with chronic rhinosinusitis and primary ciliary dyskinesia.

  4. DNAH5 (rs2277046) is associated with single nucleotide polymorphisms in Korean patients, either non-segmental or segmental type.

  5. DNAH5 is the cause of primary ciliary dyskinesia in two siblings in a nuclear family as identified by whole genome sequencing.

  6. immunofluorescence studies of respiratory epithelial cells with secondary ciliary dyskinesia identified in vitro and in vivo normal axonemal DNAH5 localization

  7. DNAH5 is frequently mutated in patients with primary ciliary dyskinesia exhibiting outer dynein arm defects and mutations cluster in five exons.

  8. Two dynein genes, encoding ODA intermediate chain (DNAI1 (show DNAI1 Antibodies)) and heavy chain (DNAH5), have been seen to be mutated in approximately 30-38% of the families

  9. Although genetic alterations remain to be identified in most patients, DNAH5 is to date the main PCD gene.

  10. Two "major" genes, DNAI1 and DNAH5, underlie PCD in nearly half of the patients with ODA defects

Mouse (Murine) Dynein, Axonemal, Heavy Chain 5 (Dnah5) interaction partners

  1. Dnah6 (show DNAH6 Antibodies) genetically interacts with Dnai1 (show DNAI1 Antibodies) and Dnah5 to cause heterotaxy and primary ciliary dyskinesia.

  2. Loss of function of Mdnah5 causes primary ciliary dyskinesia and hydrocephalus

  3. These findings are consistent with studies indicating that perturbations in dynein activity can contribute to the aberrant accumulations of neurofilaments that accompany ALS/motor neuron disease.

  4. Dnahc5 is required for the specification of left-right asymmetry and suggest that the PCD (show PCBD1 Antibodies)-causing Dnahc5 mutation may also be associated with heterotaxy.

Dnah5 Antigen Profile

Protein Summary

This gene encodes a dynein protein, which is part of a microtubule-associated motor protein complex consisting of heavy, light, and intermediate chains. This protein is an axonemal heavy chain dynein. It functions as a force-generating protein with ATPase activity, whereby the release of ADP is thought to produce the force-producing power stroke. Mutations in this gene cause primary ciliary dyskinesia type 3, as well as Kartagener syndrome, which are both diseases due to ciliary defects.

Gene names and symbols associated with Dnah5

  • dynein, axonemal, heavy chain 5 (DNAH5) antibody
  • dynein, axonemal, heavy chain 5 (dnah5) antibody
  • dynein, axonemal, heavy chain 5 (Dnah5) antibody
  • AU022615 antibody
  • b2b601Clo antibody
  • b2b1134Clo antibody
  • b2b1154Clo antibody
  • b2b1537Clo antibody
  • b2b1565Clo antibody
  • CILD3 antibody
  • DLP5 antibody
  • Dnahc5 antibody
  • Dnahc8 antibody
  • HL1 antibody
  • KTGNR antibody
  • Mdnah5 antibody
  • mKIAA1603 antibody
  • PCD antibody

Protein level used designations for Dnah5

dynein, axonemal, heavy chain 5 , dynein, axonemal, heavy polypeptide 5 , dynein heavy chain 5, axonemal-like , axonemal beta dynein heavy chain 5 , ciliary dynein heavy chain 5 , dynein heavy chain 5, axonemal , axonemal dynein heavy chain 5 , dynein, axon, heavy chain 5 , dynein heavy chain , dynein-like protein 5 , dynein-like prot ein 5

GENE ID SPECIES
420921 Gallus gallus
461726 Pan troglodytes
522856 Bos taurus
606983 Canis lupus familiaris
717339 Macaca mulatta
725479 Apis mellifera
100020164 Monodelphis domestica
100070308 Equus caballus
100089977 Ornithorhynchus anatinus
100182341 Ciona intestinalis
100209217 Hydra magnipapillata
100373093 Saccoglossus kowalevskii
100389549 Callithrix jacchus
100462929 Xenopus laevis
100551100 Meleagris gallopavo
100638612 Amphimedon queenslandica
1767 Homo sapiens
110082 Mus musculus
294854 Rattus norvegicus
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