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anti-Dystrobrevin alpha (DTNA) Antibodies

The protein encoded by DTNA belongs to the dystrobrevin subfamily of the dystrophin family. Additionally we are shipping DTNA Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DTNA 13527 Q9D2N4
DTNA 1837 Q9Y4J8
DTNA 307548  
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Top anti-DTNA Antibodies at antibodies-online.com

Showing 10 out of 80 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated IF, IHC (p), WB DTNA Antibody (C-term)  western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the DTNA antibody detected the DTNA protein (arrow). DTNA Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DTNA Antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Confocal immunofluorescent analysis of DTNA / DRP3 Antibody (C-term) Cat.-No AP51329PU-N with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). Formalin fixed and paraffin embedded human brain tissue stained with DTNA / DRP3 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC223952 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-DTNA antibody (ABIN2454067), and then analyzed by flow cytometry. Anti-DTNA mouse monoclonal antibody (ABIN2454067) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DTNA (RC223952). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, WB Anti-DTNA mouse monoclonal antibody (ABIN2454080) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DTNA (RC223952). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DTNA (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-DTNA. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells transfected with either RC223952 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-DTNA antibody (ABIN2454104), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DTNA (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-DTNA. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Mouse Rabbit Un-conjugated IF, IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Mouse Un-conjugated FACS   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated WB Western Blot analysis of DTNA expression in transfected 293T cell line by DTNA MaxPab polyclonal antibody.Lane 1: DTNA transfected lysate(75.46 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details

DTNA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-DTNA Antibodies

  1. Mouse (Murine) Polyclonal DTNA Primary Antibody for IF, IHC (p) - ABIN656504 : Böhm, Constantinou, Tan, Jin, Roberts: Profound human/mouse differences in alpha-dystrobrevin isoforms: a novel syntrophin-binding site and promoter missing in mouse and rat. in BMC biology 2009 (PubMed)
    Show all 2 references for ABIN656504

  2. Human Polyclonal DTNA Primary Antibody for EIA, IF - ABIN951988 : Hanna, Kruskal, Ezekowitz, Bloom, Collier: Role of macrophage oxidative burst in the action of anthrax lethal toxin. in Molecular medicine (Cambridge, Mass.) 1996 (PubMed)

More Antibodies against DTNA Interaction Partners

Zebrafish Dystrobrevin alpha (DTNA) interaction partners

  1. Ordered disorder of the astrocytic dystrophin (show DMD Antibodies)-associated protein complex in the norm and pathology.

Mouse (Murine) Dystrobrevin alpha (DTNA) interaction partners

  1. Alpha-dystrobrevin is a multifunctional protein that increases dystrophin's binding to the dystrophin (show DMD Antibodies)-glycoprotein complex.

  2. Loss of alpha dystrobrevin is associated with perturbation in cell cycle progression and nuclei shape.

  3. Ordered disorder of the astrocytic dystrophin (show DMD Antibodies)-associated protein complex in the norm and pathology.

  4. alpha-dystrobrevin emerges as a central organizer of dystrophin (show DMD Antibodies)-associated protein in glial endfeet and a rare example of a glial protein with a role in maintaining BBB (show ALMS1 Antibodies) function

  5. the interaction between alpha-catulin (show CTNNAL1 Antibodies) and alpha-dystrobrevin is evolutionarily conserved in C. elegans and mouse muscles and strongly suggests that this interaction contributes to the integrity of the dystrophin (show DMD Antibodies) complex

  6. The ErbB2 (show ERBB2 Antibodies) signaling maintains high efficacy of synaptic transmission by stabilizing the postsynaptic apparatus via phosphorylation of alpha-dystrobrevin1.

  7. This is the first demonstration in which assembly of an astroglial protein scaffold containing syntrophin and dystrophin (show DMD Antibodies) in perivascular astrocytes is dependent on the presence of alpha-dystrobrevin.

  8. Fundamental functional differences between the alpha-dystrobrevins of mice and humans raises questions about the use of the mouse as a model animal for Duchenne muscular dystrophy (show DMD Antibodies).

  9. identified a new dystrobrevin-associated protein, DAMAGE; interacts with the N-terminal region of alpha-dystrobrevin

  10. kinetics of the dystrobrevin-Kif5A interaction showed a lower affinity of alpha compared to that of beta-dystrobrevin for binding to kinesin

Human Dystrobrevin alpha (DTNA) interaction partners

  1. our findings suggest that novel mutations in FAM136A and DTNA genes are probably causal variants in FMD (show FLNA Antibodies).

  2. Ordered disorder of the astrocytic dystrophin (show DMD Antibodies)-associated protein complex in the norm and pathology.

  3. Results suggest that alpha-dystrobrevin isoforms play a central role in cytoskeleton reorganization via their multiple interactions with actin and actin-associating proteins.

  4. Data show that alpha-dystrobrevin-1 recruits alpha-catulin (show CTNNAL1 Antibodies), which supersensitizes alpha(1D)-AR functional responses by recruiting effector molecules to the signalosome.

  5. Fundamental functional differences between the alpha-dystrobrevins of mice and humans raises questions about the use of the mouse as a model animal for Duchenne muscular dystrophy (show DMD Antibodies).

  6. During a cycle of regeneration in tibialis anterior muscle following myonecrosis, alpha-dystrobrevin reaches 50% of the protein level on day 28 by 6.6 days, regenerating more slowly than dystrophin (show DMD Antibodies).

  7. alpha-dystrobrevin and its splice isoforms have a role in signal transduction in myeloid cells during induction of granulocytic differentiation and/or at the commitment stage of differentiation or phagocytic cells

  8. Transgenic expression of either isoform of alpha-dystrobrevin prevented muscle fiber degeneration in knockout mice; however, only alphaDB1 corrected defects at neuromuscular and musculotendinous junctions.

  9. patients with deficiency of beta2-syntrophin and alpha-dystrobrevin presented with severe congenital weakness and died in the first year, and patients with deficiency of alpha-DNT (show NT5C Antibodies) had congenital muscular dystrophy with complete external ophthalmoplegia.

  10. findings suggest that a-dystrobrevin specifically is associated with the tight junctions during their reorganization

DTNA Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with DTNA

  • dystrobrevin, alpha (DTNA) antibody
  • dystrobrevin, alpha (dtna) antibody
  • dystrobrevin alpha (dyb-1) antibody
  • dystrobrevin alpha (Dtna) antibody
  • dystrobrevin alpha-like (LOC100627907) antibody
  • dystrobrevin, alpha (Dtna) antibody
  • 2210407P21Rik antibody
  • a-DB-1 antibody
  • A0 antibody
  • adbn antibody
  • adtn antibody
  • atnb antibody
  • D18S892E antibody
  • DRP3 antibody
  • DTN antibody
  • DTN-A antibody
  • Dtna-ps1 antibody
  • LVNC1 antibody
  • MGC146484 antibody
  • RGD1561985 antibody

Protein level used designations for DTNA

alpha-dystrobrevin isoform 1a- , alpha-dystrobrevin isoform 1b+ , alpha-dystrobrevin isoform 1c- , alpha-dystrobrevin isoform 4a- , dystrobrevin, alpha , dystrobrevin alpha , Dystrobrevin alpha , DTN-A , alpha-dystrobrevin , dystrophin-related protein 3 , dystrobrevin alpha, pseudogene 1

GENE ID SPECIES
421104 Gallus gallus
455367 Pan troglodytes
794932 Danio rerio
100195747 Salmo salar
100351412 Oryctolagus cuniculus
779813 Xenopus (Silurana) tropicalis
13527 Mus musculus
100627907 Sus scrofa
1837 Homo sapiens
490488 Canis lupus familiaris
541153 Bos taurus
307548 Rattus norvegicus
Selected quality suppliers for anti-DTNA (DTNA) Antibodies
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