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Dystrobrevin alpha Proteins (DTNA)

The protein encoded by DTNA belongs to the dystrobrevin subfamily of the dystrophin family. Additionally we are shipping DTNA Antibodies (78) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DTNA 13527 Q9D2N4
DTNA 1837 Q9Y4J8
Rat DTNA DTNA 307548  
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Top DTNA Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

DTNA Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Dystrobrevin alpha (DTNA) Interaction Partners

Zebrafish Dystrobrevin alpha (DTNA) interaction partners

  1. Ordered disorder of the astrocytic dystrophin (show DMD Proteins)-associated protein complex in the norm and pathology.

Mouse (Murine) Dystrobrevin alpha (DTNA) interaction partners

  1. Alpha-dystrobrevin is a multifunctional protein that increases dystrophin's binding to the dystrophin (show DMD Proteins)-glycoprotein complex.

  2. Loss of alpha dystrobrevin is associated with perturbation in cell cycle progression and nuclei shape.

  3. Ordered disorder of the astrocytic dystrophin (show DMD Proteins)-associated protein complex in the norm and pathology.

  4. alpha-dystrobrevin emerges as a central organizer of dystrophin-associated protein in glial endfeet and a rare example of a glial protein with a role in maintaining BBB function

  5. the interaction between alpha-catulin (show CTNNAL1 Proteins) and alpha-dystrobrevin is evolutionarily conserved in C. elegans and mouse muscles and strongly suggests that this interaction contributes to the integrity of the dystrophin (show DMD Proteins) complex

  6. The ErbB2 (show ERBB2 Proteins) signaling maintains high efficacy of synaptic transmission by stabilizing the postsynaptic apparatus via phosphorylation of alpha-dystrobrevin1.

  7. This is the first demonstration in which assembly of an astroglial protein scaffold containing syntrophin and dystrophin (show DMD Proteins) in perivascular astrocytes is dependent on the presence of alpha-dystrobrevin.

  8. Fundamental functional differences between the alpha-dystrobrevins of mice and humans raises questions about the use of the mouse as a model animal for Duchenne muscular dystrophy (show DMD Proteins).

  9. identified a new dystrobrevin-associated protein, DAMAGE; interacts with the N-terminal region of alpha-dystrobrevin

  10. kinetics of the dystrobrevin-Kif5A interaction showed a lower affinity of alpha compared to that of beta-dystrobrevin for binding to kinesin

Human Dystrobrevin alpha (DTNA) interaction partners

  1. our findings suggest that novel mutations in FAM136A and DTNA genes are probably causal variants in FMD (show FLNA Proteins).

  2. Ordered disorder of the astrocytic dystrophin (show DMD Proteins)-associated protein complex in the norm and pathology.

  3. Results suggest that alpha-dystrobrevin isoforms play a central role in cytoskeleton reorganization via their multiple interactions with actin and actin-associating proteins.

  4. Data show that alpha-dystrobrevin-1 recruits alpha-catulin (show CTNNAL1 Proteins), which supersensitizes alpha(1D)-AR functional responses by recruiting effector molecules to the signalosome.

  5. Fundamental functional differences between the alpha-dystrobrevins of mice and humans raises questions about the use of the mouse as a model animal for Duchenne muscular dystrophy (show DMD Proteins).

  6. During a cycle of regeneration in tibialis anterior muscle following myonecrosis, alpha-dystrobrevin reaches 50% of the protein level on day 28 by 6.6 days, regenerating more slowly than dystrophin (show DMD Proteins).

  7. alpha-dystrobrevin and its splice isoforms have a role in signal transduction in myeloid cells during induction of granulocytic differentiation and/or at the commitment stage of differentiation or phagocytic cells

  8. Transgenic expression of either isoform of alpha-dystrobrevin prevented muscle fiber degeneration in knockout mice; however, only alphaDB1 corrected defects at neuromuscular and musculotendinous junctions.

  9. patients with deficiency of beta2-syntrophin and alpha-dystrobrevin presented with severe congenital weakness and died in the first year, and patients with deficiency of alpha-DNT (show NT5C Proteins) had congenital muscular dystrophy with complete external ophthalmoplegia.

  10. findings suggest that a-dystrobrevin specifically is associated with the tight junctions during their reorganization

DTNA Protein Profile

Protein Summary

The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with Dystrobrevin alpha Proteins (DTNA)

  • dystrobrevin, alpha (DTNA)
  • dystrobrevin, alpha (dtna)
  • dystrobrevin alpha (dyb-1)
  • dystrobrevin alpha (Dtna)
  • dystrobrevin alpha-like (LOC100627907)
  • dystrobrevin, alpha (Dtna)
  • 2210407P21Rik protein
  • a-DB-1 protein
  • A0 protein
  • adbn protein
  • adtn protein
  • atnb protein
  • D18S892E protein
  • DRP3 protein
  • DTN protein
  • DTN-A protein
  • Dtna-ps1 protein
  • LVNC1 protein
  • MGC146484 protein
  • RGD1561985 protein

Protein level used designations for Dystrobrevin alpha Proteins (DTNA)

alpha-dystrobrevin isoform 1a- , alpha-dystrobrevin isoform 1b+ , alpha-dystrobrevin isoform 1c- , alpha-dystrobrevin isoform 4a- , dystrobrevin, alpha , dystrobrevin alpha , Dystrobrevin alpha , DTN-A , alpha-dystrobrevin , dystrophin-related protein 3 , dystrobrevin alpha, pseudogene 1

GENE ID SPECIES
421104 Gallus gallus
455367 Pan troglodytes
794932 Danio rerio
100195747 Salmo salar
100351412 Oryctolagus cuniculus
779813 Xenopus (Silurana) tropicalis
13527 Mus musculus
100627907 Sus scrofa
1837 Homo sapiens
490488 Canis lupus familiaris
541153 Bos taurus
307548 Rattus norvegicus
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