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EFCAB4B Proteins

(EF-Hand Calcium Binding Domain 4B (EFCAB4B))
Ca(2+)-binding protein that plays a key role in store- operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca(2+) concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca(2+) resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex (By similarity).
EFCAB4B Protein (AA 1-395) (GST tag) EFCAB4B Protein (AA 1-395) (GST tag) EFCAB4B Protein (AA 1-395) (GST tag) (ABIN1352375)

EFCAB4B Origin: Human Host: Wheat germ Recombinant AA, AP, ELISA, WB

EFCAB4B Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) EFCAB4B Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) EFCAB4B Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2719954)

EFCAB4B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

EFCAB4B Proteins by Origin

Find EFCAB4B Proteins for a variety of species such as anti-Human EFCAB4B. The species listed below are among those available. Click on a link to go to the corresponding products.

EFCAB4B Proteins by Source

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EFCAB4B Proteins by Protein Type

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EFCAB4B Proteins by Application

Find EFCAB4B Proteins validated for a specific application such as AP, AA, AbP, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular EFCAB4B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352375
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2719954
Quantity 20 μg
Datasheet Datasheet

Aliases for EFCAB4B Proteins

calcium release activated channel regulator 2A (CRACR2A) Proteins
calcium release activated channel regulator 2A (Cracr2a) Proteins
CRACR2A Proteins
Gm462 Proteins
Gm1073 Proteins
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