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EGFL6 encodes a member of the epidermal growth factor (EGF) repeat superfamily. Additionally we are shipping EGFL6 Kits (7) and EGFL6 Proteins (7) and many more products for this protein.
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EGFL6 is an angiocrine and tumor cell factor that promotes tumorigenesis via SHP2-mediated signaling. EGFL6 stimulates ALDH+ ovarian cancer stem cell to migrate and undergo asymmetric division.
EGFL6 was overexpressed in benign meningioma tissues and serum.
results indicate that human EGFL6 is a paracrine/autocrine growth factor of adipose tissue up-regulated in obesity and potentially involved in the process of adipose tissue expansion and the development of obesity
There is an absence of GNAS (show GNAS Antibodies) and EGFL6 mutations in common human cancers.
MAEG may play a role as a mediator regulating epithelial-mesenchymal interaction through binding to RGD-binding integrins including alpha8beta1 during hair follicle development.
This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted\; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence\; an arg-gly-asp integrin association motif\; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors.
EGF repeat-containing protein 6
, EGF-like protein 6
, MAM and EGF domain containing
, MAM and EGF domains-containing gene protein
, epidermal growth factor-like protein 6
, EGF-like domain-containing protein 6
, multiple EGF-like domain protein 6
, multiple epidermal growth factor-like domain protein 6