ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B) Proteins (ELAVL2)

The protein encoded by ELAVL2 is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. Additionally we are shipping ELAVL2 Antibodies (79) and ELAVL2 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ELAVL2 1993 Q12926
ELAVL2 15569 Q60899
ELAVL2 286973  
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Top ELAVL2 Proteins at antibodies-online.com

Showing 9 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 11 Days
$341.00
Details
Yeast Human His tag   50 μg Log in to see 8 to 11 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Yeast Pongo abelii His tag   1 mg Log in to see 60 to 71 Days
$2,979.17
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,979.17
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 60 to 71 Days
$3,030.50
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 60 to 71 Days
$3,072.67
Details

ELAVL2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B) (ELAVL2) Interaction Partners

Human ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B) (ELAVL2) interaction partners

  1. ELAVL2-regulated co-expression networks are also enriched for neurodevelopmental and synaptic genes, and include genes with human-specific patterns of expression in the frontal pole. Together, these data suggest that ELAVL2 regulation of transcript expression is critical for neuronal function and clinically relevant to autism

  2. Tests for gene-environment interaction between these 33 genes and maternal smoking found evidence for interaction with two additional genes: GRID2 (show GRID2 Proteins) and ELAVL2 among European mothers

  3. the mutually antagonistic action of two RNA-binding proteins, Hu and hnRNP K (show HNRNPK Proteins), control the timing of the switch from proliferation to neuronal differentiation through the post-transcriptional regulation of p21 (show CDKN1A Proteins) mRNA

Mouse (Murine) ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B) (ELAVL2) interaction partners

  1. ELAVL2 has an ambivalent role in oocytes: it functions as a pleiotropic translational repressor in efficient production of grown oocytes, while its disposal during the NSN/SN transition contributes to the acquisition of full developmental competence.

  2. The predominant expression of REST4, HuB/C/D and nPTB (show PTBP2 Proteins) in post-mitotic fiber cells, together with miR (show MLXIP Proteins)-124 expression in vertebrate lenses, was shown.

  3. the mutually antagonistic action of two RNA-binding proteins, Hu and hnRNP K (show HNRNPK Proteins), control the timing of the switch from proliferation to neuronal differentiation through the post-transcriptional regulation of p21 mRNA

Xenopus laevis ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B) (ELAVL2) interaction partners

  1. elrB expression was not detected in Xenopus retina ganglion cell layer until stage 32.

  2. direct correlation between ElrB binding and translational repression by the Vg1 3'-UTR

  3. Data show that, while ElrA and ElrB are 69% identical and both exhibit RNA binding in the nM range, recombinant ElrB, but not ElrA, is able to oligomerise.

  4. Report on the identification of Xenopus ElrA/B proteins and show that Elr-type proteins are part of one RNP (show RNPC3 Proteins) complex together with other localization proteins from Xenopus oocytes.

ELAVL2 Protein Profile

Protein Summary

The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with ELAVL2

  • ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) (ELAVL2)
  • ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) (Elavl2)
  • ELAV (embryonic lethal, abnormal vision)-like 2 (Hu antigen B) (elavl2-a)
  • el-1 protein
  • Elav2 protein
  • elavl2 protein
  • elrB protein
  • hel-n1 protein
  • heln1 protein
  • hub protein
  • mel-N1 protein
  • p45 protein
  • Xel-1 protein

Protein level used designations for ELAVL2

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) , ELAV-like neuronal protein 1 , ELAV-like protein 2 , hu-antigen B , nervous system-specific RNA-binding protein Hel-N1 , ELAV-like 2 , HU-antigen B , nervous system-specific RNA-binding protein Mel-N1 , RNA binding protein HuB , embryonic lethal, abnormal vision-like 2 , Elav like-1 , Protein ElrB

GENE ID SPECIES
100286845 Bos taurus
1993 Homo sapiens
15569 Mus musculus
286973 Rattus norvegicus
100174484 Pongo abelii
394342 Xenopus laevis
Selected quality suppliers for ELAVL2 Proteins (ELAVL2)
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