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anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) Antibodies

Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. Additionally we are shipping EDEM1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EDEM1 9695 Q92611
EDEM1 192193 Q925U4
EDEM1 297504  
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Top anti-EDEM1 Antibodies at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-EDEM1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$336.00
Details
Cow Rabbit Un-conjugated WB Western blot analysis of EDEM1 expression in HEK293T (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$449.17
Details
Human Rabbit Un-conjugated WB EDEM1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated IHC   0.1 mg Log in to see 5 to 7 Days
$330.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged EDEM1 is 0.1 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.52 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$375.83
Details
Mouse Rabbit Un-conjugated WB   100 μg Log in to see 8 to 10 Days
$683.83
Details

EDEM1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
,
,
Mouse (Murine) ,


Rat (Rattus)


Top referenced anti-EDEM1 Antibodies

  1. Human Polyclonal EDEM1 Primary Antibody for IHC - ABIN966027 : Nagase, Seki, Ishikawa, Ohira, Kawarabayasi, Ohara, Tanaka, Kotani, Miyajima, Nomura: Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. in DNA research : an international journal for rapid publication of reports on genes and genomes 1997 (PubMed)
    Show all 2 references for ABIN966027

  2. Chicken Polyclonal EDEM1 Primary Antibody for WB - ABIN2782826 : Zuber, Cormier, Guhl, Santimaria, Hebert, Roth: EDEM1 reveals a quality control vesicular transport pathway out of the endoplasmic reticulum not involving the COPII exit sites. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)

More Antibodies against EDEM1 Interaction Partners

Human ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) interaction partners

  1. EDEM1 colocalizes with the selective autophagy cargo receptors p62/SQSTM1 (show SQSTM1 Antibodies), neighbor of BRCA1 gene 1 (NBR1 (show NBR1 Antibodies)) and autophagy-linked FYVE (Alfy (show WDFY3 Antibodies)) protein, and becomes engulfed by autophagic isolation membranes.

  2. Endoplasmic reticulum degradation-enhancing alpha-mannosidase-like protein 1 targets misfolded HLA-B27 dimers for endoplasmic reticulum-associated degradation.

  3. miR (show MLXIP Antibodies)-581 promotes hepatitis B virus surface antigen expression by targeting Dicer (show DICER1 Antibodies) and EDEM1 in HepG2 cells.

  4. EDEM1 associates with lifespan in animal models, although not humans.

  5. analysis of a shared endoplasmic reticulum-associated degradation pathway involving the EDEM1 protein for glycosylated and nonglycosylated proteins

  6. Tyrosinase (show TYR Antibodies) degradation is prevented when EDEM1 lacks the intrinsically disordered region

  7. we suggest that a nascent glycoprotein can normally dissociate from EDEM1 and be rescued from endoplasmic reticulum associated degradation by reentering calnexin (show CANX Antibodies)-refolding cycles

  8. signal sequence cleavage functionally regulated the association of EDEM1-soluble and membrane-integrated isoforms with distinct ERAD machinery and substrates.

  9. EDEM1 protein recognition may be determined by the structure of the endoplasmic reticulum-associated protein degradation substrate in a study of mutant ricin A-chain transport to the cytosol.

  10. mannose trimming enables delivery of a substrate glycoprotein from EDEM1 to late endoplasmic reticulum degredation steps through association with XTP3-B (show ERLEC1 Antibodies)

Mouse (Murine) ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) interaction partners

  1. Japanese encephalitis virus replication is negatively regulated by autophagy and occurs on LC3 (show MAP1LC3A Antibodies)-I- and EDEM1-containing membranes

  2. Data suggest Edem1/Edem2 (show EDEM2 Antibodies) participate in ricin translocation; overexpression of Edem2 (show EDEM2 Antibodies), in contrast to Edem1, promotes ricin subunit A transport from endoplasmic reticulum (ER) to cytosol; transport of ricin P250A mutant is Edem1/Edem2 (show EDEM2 Antibodies)-independent.

  3. analysis of a shared endoplasmic reticulum-associated degradation pathway involving the EDEM1 protein for glycosylated and nonglycosylated proteins

  4. role of the lectins Htm1p/EDEM in the degradation process of CFTR (show CFTR Antibodies)

  5. EDEM has a role in maintenance of protein folding efficiency and secretory capacity

  6. EDEM is involved in retrotranslocation of ricin from the ER to the cytosol.

  7. Cells with defective EDEM1 turnover contain unphysiologically high levels of EDEM1, show enhanced ER associated degradation activity and are characterized by impaired capacity to efficiently complete maturation of model glycopolypeptides.

EDEM1 Antigen Profile

Protein Summary

Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It lacks mannosidase activity.

Gene names and symbols associated with EDEM1

  • ER degradation enhancer, mannosidase alpha-like 1 (edem1) antibody
  • ER degradation enhancer, mannosidase alpha-like 1 (EDEM1) antibody
  • ER degradation enhancer, mannosidase alpha-like 1 (Edem1) antibody
  • A130059K23Rik antibody
  • EDEM antibody
  • EDEM1 antibody
  • mKIAA0212 antibody
  • RGD1563633 antibody
  • zgc:55816 antibody

Protein level used designations for EDEM1

ER degradation-enhancing alpha-mannosidase-like 1 , ER degradation enhancer, mannosidase alpha-like 1 , ER degradation-enhancing alpha-mannosidase-like 1-like , ER degradation-enhancing alpha-mannosidase-like protein 1 , ER degradation ER degradation enhancer, mannosidase alpha-like 1

GENE ID SPECIES
394164 Danio rerio
395034 Xenopus (Silurana) tropicalis
476547 Canis lupus familiaris
703085 Macaca mulatta
100013430 Monodelphis domestica
100075916 Ornithorhynchus anatinus
100380799 Salmo salar
100388997 Callithrix jacchus
100468417 Ailuropoda melanoleuca
100543065 Meleagris gallopavo
100567845 Anolis carolinensis
100637820 Amphimedon queenslandica
100049149 Xenopus laevis
416110 Gallus gallus
9695 Homo sapiens
511008 Bos taurus
192193 Mus musculus
297504 Rattus norvegicus
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