Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
EBF3 encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. Additionally we are shipping EBF3 Proteins (4) and many more products for this protein.
Showing 10 out of 40 products:
Human Monoclonal EBF3 Primary Antibody for IHC (p), ELISA - ABIN566977
Nasrallah, Cho, Simonet, Putt, Kitamura, Golden: Differential effects of a polyalanine tract expansion in Arx on neural development and gene expression. in Human molecular genetics 2012
Show all 2 Pubmed References
Cow (Bovine) Polyclonal EBF3 Primary Antibody for WB - ABIN2777449
Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003
Show all 2 Pubmed References
Our findings highlight the critical role of Ebf3 in multipolar-to-bipolar transition via positive feedback regulation of NeuroD1 in the developing neocortex.
EB3 (show MAPRE3 Antibodies) binds to IP3 receptors, promotes IP3R (show ITPR1 Antibodies) clustering and Ca2 (show CA2 Antibodies)+ signals in endothelial cells.
Ebf3 is a new regulator of terminal muscle differentiation in the diaphragm, and Ebf (show EBF1 Antibodies) factors cooperate with MyoD (show MYOD1 Antibodies) in the induction of muscle-specific (show EIF3K Antibodies) genes
The regulation of Ebf3 expression by miR218 controls the terminal differentiation of dopaminergic neurons.
MAP1B (show MAP1B Antibodies) interacts directly with EB1 (show MAPRE1 Antibodies) and EB3 (show MAPRE3 Antibodies) (EBs), two core 'microtubule plus-end tracking proteins' ( TIPs), and sequesters them in the cytosol of developing neuronal cells.
Ebf2 (show EBF2 Antibodies) and Ebf3, singly or together, control the migration of Cajal-Retzius cells arising in the cortical hem. These findings provide evidence that Ebfs directly regulate Cajal-Retzius cell development
DDA3 (show PSRC1 Antibodies) is a novel microtubule-associated protein (show SPAG5 Antibodies) that binds to EB3 (show MAPRE3 Antibodies), and results implicate DDA3 (show PSRC1 Antibodies) and EB3 (show MAPRE3 Antibodies) in the beta-catenin (show CTNNB1 Antibodies)-mediated growth signaling.
Two +TIPs, CLIP-170 (show CLIP1 Antibodies) and end-binding protein 3 (EB3 (show MAPRE3 Antibodies)), turn over rapidly on MT ends. Diffusion of CLIP-170 (show CLIP1 Antibodies) and EB3 (show MAPRE3 Antibodies) appears to be rate limiting for their binding to MT plus ends.
Data revealed that expression of DNA binding inhibitor 3 (show PPP1R11 Antibodies), early B cell factor 2 (show EBF2 Antibodies), Ebf3, Iroquois related homeobox 1 (show IRX1 Antibodies), Kruppel-like factor 7 , mab-21-like 1 (show MAB21L1 Antibodies) , fatty acid binding protein 7 (show FABP7 Antibodies) and stathmin-like 4 (show STMN4 Antibodies),were enriched in the diencephalon of zebrafish.
In 11 affected individuals from 11 unrelated families, we identified de novo variants in EBF3 (show MAPRE3 Antibodies) as potentially causative for the neurodevelopmental phenotype. The variants include one nonsense, two frameshift deletions, one splice, and three missense variants. There are three de novo missense variants, (p.(Lys64Thr), p.(His157Gln), and p.(Arg209Gln), which are all in the COE1 (show EBF1 Antibodies) DNA-binding domain.
EBF3 (show MAPRE3 Antibodies), a transcription factor previously unknown to be associated with human disease, is important for brain and other organ development and warrants further investigation
findings indicate that mutations in EBF3 cause a genetic neurodevelopmental syndrome and suggest that loss of EBF3 function might mediate a subset of neurologic phenotypes shared by ARX-related disorders, including intellectual disability, abnormal genitalia, and structural CNS malformations
findings demonstrate that variants disrupting EBF3 (show MAPRE3 Antibodies)-mediated transcriptional regulation cause intellectual disability and developmental delay and are present in approximately 0.1% of individuals with unexplained neurodevelopmental disorders
Early B-cell factor 3 (EBF3) is a novel tumor suppressor gene with promoter hypermethylation in pediatric acute myeloid leukemia (show BCL11A Antibodies)
EBF3 (show MAPRE3 Antibodies) tumor suppressor is epigenetically silenced and that it serves as an independent prognostic marker in gastric carcinoma.
Results verify IRX1 (show IRX3 Antibodies), EBF3 (show MAPRE3 Antibodies), SLC5A8 (show SLC5A8 Antibodies), SEPT9 (show SEPT9 Antibodies), and FUSSEL18 (show SKOR2 Antibodies) as valid methylation markers in two separate sets of HNSCC specimens; also preliminarily show a trend between HPV16 positivity and target gene hypermethylation of IRX1 (show IRX3 Antibodies), EBF3 (show MAPRE3 Antibodies), SLC5A8 (show SLC5A8 Antibodies), and SEPT9 (show SEPT9 Antibodies).
Findings suggested that the transfection of EBF3 (show MAPRE3 Antibodies) gene into HepG2 induced the cell proliferation from G1 phase to G2 phase by increasing the number of cells.
Expression of EBF3 resulted in cell cycle arrest and apoptosis. EBF3 regulates a transcriptional program underlying a putative tumor suppression pathway.
Frequent methylation of EBF3 (show MAPRE3 Antibodies) gene is associated with head and neck squamous cell carcinoma
This gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma.
early B-cell factor 3
, Olf-1/EBF-like 2
, transcription factor COE3
, olf-1/EBF-like 2
, EB1 protein family member 3
, end-binding protein 3
, microtubule-associated protein RP/EB family member 3