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Elongation Factor, RNA Polymerase II, 2 Proteins (ELL2)

Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.. Additionally we are shipping ELL2 Antibodies (55) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ELL2 192657 Q3UKU1
Rat ELL2 ELL2 309918  
ELL2 22936 O00472
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Top ELL2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

ELL2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Elongation Factor, RNA Polymerase II, 2 (ELL2) Interaction Partners

Mouse (Murine) Elongation Factor, RNA Polymerase II, 2 (ELL2) interaction partners

  1. Deletion of the Ell2 gene in mice results in loss of Ig secretion from plasma cells and reduced expression of a number of other genes involved in secretion and the unfol (show XBP1 Proteins)ded pr (show ATF6 Proteins)otein (show HSPA5 Proteins) response l (show CCNB2 Proteins)ike XBP1, Oc (show POU2AF1 Proteins)aB (BOB1, (show POU2AF1 Proteins) Pou2af1), cyclin B2 and Ig light chain

  2. The splicing factor hnRNPLL and the transcription elongation factor ELL2 modulate the ratio of secred versus membrane-encoding Ighg2b transcripts at the expense of the secreted isoform.

  3. ELL2 enhanced both polyadenylation and exon skipping with the gene encoding the immunoglobulin heavy-chain complex (Igh) and reporter constructs

Human Elongation Factor, RNA Polymerase II, 2 (ELL2) interaction partners

  1. multiple myeloma risk allele harbours a Thr298Ala missense variant in an ELL2 domain required for transcription elongation

  2. Tax (show CNTN2 Proteins) transactivates the ELL2 promoter in HTLV-1-infected T-cells.

  3. Loss of ELL2 in B cells results in decreased Igh secretory mRNA and decreased expression of Ig light chain plus genes involved in the unfolded protein response like XBP1 (show XBP1 Proteins), ATF6 (show ATF6 Proteins), BiP (show GDF10 Proteins), cyclin B2 (show CCNB2 Proteins), OcaB (BOB1 (show POU2AF1 Proteins), Pou2af1 (show POU2AF1 Proteins)).

  4. Prostratin and HMBA, two well-studied activators of HIV transcription and latency, enhance ELL2 accumulation and SECs formation largely through decreasing Siah1 (show SIAH1 Proteins) expression and ELL2 polyubiquitination.

  5. ELL2 addition regulates mRNA processing by enhancing poly(A) site choice and exon splice-site skipping

ELL2 Protein Profile

Protein Summary

Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.

Gene names and symbols associated with ELL2

  • elongation factor, RNA polymerase II, 2 (ELL2)
  • elongation factor, RNA polymerase II, 2 (ell2)
  • elongation factor RNA polymerase II 2 (Ell2)
  • cb244 protein
  • ELL2 protein
  • fb78f03 protein
  • im:3814960 protein
  • MGC82755 protein
  • sb:cb244 protein
  • wu:fb78f03 protein
  • xell2 protein

Protein level used designations for ELL2

RNA polymerase II elongation factor ELL2 , elongation factor, RNA polymerase II, 2 , elongation factor, RNA polymerase 2, 2 , RNA polymerase II elongation factor ELL2-like , ELL-related RNA polymerase II, elongation factor , eleven-nineteen lysine-rich leukemia gene 2

GENE ID SPECIES
782605 Bos taurus
100523777 Sus scrofa
100064911 Equus caballus
322997 Danio rerio
427119 Gallus gallus
447018 Xenopus laevis
461741 Pan troglodytes
488899 Canis lupus familiaris
100038075 Xenopus (Silurana) tropicalis
100404238 Callithrix jacchus
100437631 Pongo abelii
192657 Mus musculus
309918 Rattus norvegicus
22936 Homo sapiens
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