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Elongation Factor Tu GTP Binding Domain Containing 2 Proteins (EFTUD2)

EFTUD2 encodes a GTPase which is a component of the spliceosome complex which processes precursor mRNAs to produce mature mRNAs. Additionally we are shipping Elongation Factor Tu GTP Binding Domain Containing 2 Antibodies (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EFTUD2 9343 Q15029
Mouse EFTUD2 EFTUD2 20624 O08810
Rat EFTUD2 EFTUD2 287739  
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Top Elongation Factor Tu GTP Binding Domain Containing 2 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

EFTUD2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Elongation Factor Tu GTP Binding Domain Containing 2 (EFTUD2) Interaction Partners

Human Elongation Factor Tu GTP Binding Domain Containing 2 (EFTUD2) interaction partners

  1. An update on mandibulofacial dysostosis with microcephaly and EFTUD2 mutations has been presented. (Review)

  2. Novel heterozygous mutations in EFTUD2, detected by exome sequencing, in mandibulofacial dysostosis with Microcephaly syndrome.

  3. Results show that SNW1 (show SNW1 Proteins) directly associates with EFTUD2 and SNRNP200 and that disruption of SNW1 (show SNW1 Proteins) association with these proteins promotes the apoptosis of breast cancer cells.

  4. These data demonstrate that EFTUD2 restricts Hepatitis C Virus infection mainly through an RIG-I (show DDX58 Proteins)/MDA5 (show IFIH1 Proteins)-mediated, JAK (show JAK3 Proteins)-STAT (show STAT1 Proteins)-independent pathway, thereby revealing the participation of EFTUD2 as a novel innate immune regulator.

  5. A de nove deletion mutation at 17q21.31, encompassing the EFTUD2 gene, is associated with congenital mandibulofacial dysostosis with microcephaly.

  6. Three different mutations in EFTUD2 gene were found in patients with mandibulofacial dysostosis type Guion-Almeida syndrome

  7. Study describes loss-of-function mutations in EFTUD2 gene in patients with different clinical manifestations of Mandibulofacial dysostosis, Guion-Almeida type syndrome.

  8. the phenotype in patients with EFTUD2 mutations is much broader than previously anticipated; in addition to AFD type Guion-Almeida and syndromic esophageal atresia, oto (show PGAP1 Proteins)-facial syndrome also belongs to the EFTUD2 mutation spectrum

  9. Novel mutations in EFTUD2 were discovered in 3 patients. These mutations expand the clinical features in patients with EFTUD2 mutations and demonstrate an overlap with oculo-auriculo-vertebral spectrum.

  10. EFTUD2 haploinsufficiency leads to syndromic oesophageal atresia.

Mouse (Murine) Elongation Factor Tu GTP Binding Domain Containing 2 (EFTUD2) interaction partners

  1. Eftud2 regulates alternative splicing of MyD88 (show MYD88 Proteins) to control the innate immune response in macrophages

Elongation Factor Tu GTP Binding Domain Containing 2 (EFTUD2) Protein Profile

Protein Summary

This gene encodes a GTPase which is a component of the spliceosome complex which processes precursor mRNAs to produce mature mRNAs. Mutations in this gene are associated with mandibulofacial dysostosis with microcephaly. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with EFTUD2

  • elongation factor Tu GTP binding domain containing 2 (eftud2)
  • elongation factor Tu GTP binding domain containing 2 (EFTUD2)
  • elongation factor Tu GTP binding domain containing 2 (CpipJ_CPIJ011675)
  • elongation factor Tu GTP binding domain containing 2 (CpipJ_CPIJ016234)
  • elongation factor Tu GTP binding domain containing 2 (Eftud2)
  • 116kDa protein
  • MFDGA protein
  • MFDM protein
  • SNRNP116 protein
  • Snrp116 protein
  • Snu114 protein
  • U5-116kD protein
  • wu:fi20f05 protein
  • zgc:66214 protein

Protein level used designations for EFTUD2

116 kDa U5 small nuclear ribonucleoprotein component , U5 snRNP-specific protein, 116 kD , elongation factor Tu GTP binding domain containing 2 , 116 kDa U5 small nuclear ribonucleoprotein component-like , U5-116 kDa , U5 snRNP-specific protein, 116 kDa , elongation factor Tu GTP-binding domain protein 2 , SNU114 homolog , elongation factor Tu GTP-binding domain-containing protein 2 , hSNU114 , U5 small nuclear ribonucleoprotein 116 kDa

GENE ID SPECIES
379223 Xenopus laevis
393480 Danio rerio
454738 Pan troglodytes
594937 Xenopus (Silurana) tropicalis
715512 Macaca mulatta
6044141 Culex quinquefasciatus
6049889 Culex quinquefasciatus
100391578 Callithrix jacchus
100173557 Pongo abelii
9343 Homo sapiens
20624 Mus musculus
509425 Bos taurus
428281 Gallus gallus
490935 Canis lupus familiaris
100522208 Sus scrofa
287739 Rattus norvegicus
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