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Endosulfine alpha Proteins (ENSA)

The protein encoded by ENSA belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. Additionally we are shipping Ensa Antibodies (60) and Ensa Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ENSA 2029 O43768
ENSA 60334 P60841
ENSA 56205 P60840
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Top Ensa Proteins at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 2 to 3 Days
$217.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human GST tag Endosulfine alpha (ENSA) (AA 1-121), (full length) protein (GST tag) 1 mg Log in to see 56 to 66 Days
$1,842.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast REACT_Atlantic Salmon His tag   1 mg Log in to see 56 to 66 Days
$2,222.00
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,227.50
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,236.67
Details

ENSA Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

Top referenced Ensa Proteins

  1. Human Ensa Protein expressed in Escherichia coli (E. coli) - ABIN2181008 : Héron, Virsolvy, Apiou, Le Cam, Bataille: Isolation, characterization, and chromosomal localization of the human ENSA gene that encodes alpha-endosulfine, a regulator of beta-cell K(ATP) channels. in Diabetes 1999 (PubMed)
    Show all 3 references for ABIN2181008

  2. Human Ensa Protein expressed in Escherichia coli (E. coli) - ABIN666932 : Heron, Virsolvy, Peyrollier, Gribble, Le Cam, Ashcroft, Bataille: Human alpha-endosulfine, a possible regulator of sulfonylurea-sensitive KATP channel: molecular cloning, expression and biological properties. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)
    Show all 2 references for ABIN666932

More Proteins for Endosulfine alpha (ENSA) Interaction Partners

Human Endosulfine alpha (ENSA) interaction partners

  1. Taken together our results suggest a hierarchy of phosphatases coordinating Greatwall (show MASTL Proteins), Ensa/ARPP19 and Cdk (show CDK4 Proteins) substrate dephosphorylation during mitotic exit.

  2. Overexpressed ENSA suppresses tumor growth in an established hepatic cell line whereas hypermethylated ENSA might help maintain liver cancer initiating cells.

  3. The considerably decreased alpha-endosulfine could result in the continuous opening of K(ATP) channels and the subsequent decrease of neurotransmitters release associated with cognition in Down Syndrome.

  4. We mapped ENSA in silico to chromosome 1q21 near a confirmed type 2 diabetes susceptibility locus, and derived the genomic structure of four exons and three introns.

  5. The ENSA gene on 1q21 produces several alternatively spliced transcripts, and is located within a region linked with T2DM in diverse populations including the Pima Indians

Xenopus laevis Endosulfine alpha (ENSA) interaction partners

  1. description of how Gwl (show MASTL Proteins) activation results in PP2A (show PPP2R2B Proteins) inhibition; Arpp19 (show ARPP19 Proteins) and alpha-Endosulfine when phosphorylated by Gwl (show MASTL Proteins) associate with and inhibit PP2A (show PPP2R2B Proteins) promoting mitotic entry; endogenous Arpp19 (show ARPP19 Proteins) responsible for PP2A (show PPP2R2B Proteins) inhibition at mitotic entry in egg extracts

  2. inhibition of PP2A (show PPP2R2B Proteins)-B55delta results from Ensa, that is phosphorylated in mitosis by the protein kinase (show CSNK1D Proteins) Greatwall (show MASTL Proteins); this converts Ensa into specific inhibitor of PP2A (show PPP2R2B Proteins)-B55delta; this pathway represents a previously unknown element in mitosis control

Ensa (ENSA) Protein Profile

Protein Summary

The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene names and symbols associated with Endosulfine alpha Proteins (ENSA)

  • endosulfine alpha (ENSA)
  • endosulfine alpha (Ensa)
  • endosulfine alpha (ensa)
  • endosulfine alpha a (ensaa)
  • endosulfine alpha a (ensa)
  • 1700020C18Rik protein
  • 2610007F17Rik protein
  • AI451924 protein
  • ARPP-19e protein
  • ensa protein
  • ensaa protein
  • si:dkeyp-24a7.3 protein

Protein level used designations for Endosulfine alpha Proteins (ENSA)

alpha-endosulfine , ARPP-19e

GENE ID SPECIES
2029 Homo sapiens
60334 Rattus norvegicus
56205 Mus musculus
281142 Bos taurus
425073 Gallus gallus
397361 Sus scrofa
100196863 Salmo salar
569530 Danio rerio
379766 Xenopus laevis
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