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Can mediate aggregation most likely through a homophilic molecular interaction (By similarity).. Additionally we are shipping ESAM Antibodies (100) and ESAM Proteins (28) and many more products for this protein.
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Human ESAM ELISA Kit for Sandwich ELISA - ABIN420161
Hara, Ishida, Cangara, Hirata: Endothelial cell-selective adhesion molecule regulates albuminuria in diabetic nephropathy. in Microvascular research 2009
Show all 3 references for ABIN420161
ESAM is a novel human hematopoietic stem cell marker associated with a subset of human leukemias
Serum ESAM is higher in type 2 diabetes mellitus than in controls and parallels oxidative stress.
ESAM regulates tumor metastasis through endothelial cell migration and tube formation in metastatic nodules.
Runx3 (show RUNX3 ELISA Kits) is required for cell identity, homeostasis and function of splenic Esam(high) dendritic cells.
ESAM levels clearly mirror the shift of hematopoietic stem cells (HSC (show FUT1 ELISA Kits)) between quiescence and activation, and the intensity of expression is prominent in comparison with other HSC (show FUT1 ELISA Kits)-related antigens.
ESAM inactivation can reduce susceptibility to atherosclerosis by inhibiting plaque neovascularization and macrophage infiltration into the atheroma.
findings support a model in which ESAM localizes to platelet contacts following platelet activation in order to limit thrombus growth and stability
ESAM has a redundant functional role in physiological angiogenesis but serves a unique and essential role in pathological angiogenic processes such as tumor growth
The direct interaction between ESAM and MAGI-1 (show CNKSR3 ELISA Kits) was confirmed by pull-down experiments. The two proteins formed stable complexes in transfected CHO (show COL11A1 ELISA Kits) cells.
At endothelial tight junctions ESAM participates in the migration of neutrophils through the vessel wall, possibly by influencing endothelial cell contacts.
ESAM marks hematopoietic stem cells in murine fetal liver and will facilitate studies of hematopoiesis throughout life.
Thus, ESAM may regulate albumin (show ALB ELISA Kits) extravasation at the glomeruli and play a role in the initiation of diabetic nephropathy.
Can mediate aggregation most likely through a homophilic molecular interaction (By similarity).
endothelial cell adhesion molecule
, endothelial cell-selective adhesion molecule
, endothelial cell-specific adhesion molecule
, HUEL (C4orf1)-interacting protein
, LP4791 protein