anti-Endothelial PAS Domain Protein 1 (EPAS1) Antibodies

EPAS1 encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. antibodies-online currently ships to destinations worldwide.

list all antibodies Gene Name GeneID UniProt
EPAS1 2034 Q99814
EPAS1 13819 P97481
EPAS1 29452 Q9JHS1
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Top anti-Endothelial PAS Domain Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 202 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated WB, ChIP, FACS, ICC, IF, IHC, IHC (p), IP Staining of heart, cardiac myocytes using ABIN151063. 25 μL Login to see 9 to 11 Days
231,00
Details
Human Rabbit Un-conjugated FACS, WB EPAS1 Antibody (N-term) (ABIN654664) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the EPAS1 antibody detected the EPAS1 protein (arrow). 400 μL Login to see 2 to 4 Days
324,50
Details
Human Rabbit Un-conjugated WB EPAS1 Antibody (C-term) (ABIN658111) western blot analysis in human placenta tissue lysates (35 µg/lane). This demonstrates the EPAS1 antibody detected the EPAS1 protein (arrow). 400 μL Login to see 2 to 4 Days
324,50
Details
Human Mouse Un-conjugated WB, ChIP, FACS, ICC, IF, IHC, IHC (p), IP HIF-2 alpha detected in hypoxic human lysate using ABIN151063. Lane 1: normoxic A549 lysate control, lane 2: hypoxic A549 lysate. Staining of heart, cardiac myocytes using ABIN151063. 0.1 mL Login to see 9 to 11 Days
381,15
Details
Human Mouse Un-conjugated ICC, IF, IHC, WB Hif2alpha Western Blotting CoCl treated Hela 20ug 1 in 1000. 25 μg Login to see 3 to 4 Days
179,30
Details
Chicken Rabbit Un-conjugated WB <b>WB Suggested Anti-EPAS1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>293T cell lysate Lanes: Human placenta <br />Primary Antibody Dilution: 1:200<br />Secondary Antibody: Anti-rabbit-HRP <br />Secondary Antibody Dilution: 1:0000 <br /> Gene Name: Brown: EPAS1 Purple: Haemotoxylin <br /><br />Submitted by: EPAS1 50 μg Login to see 2 to 3 Days
289,00
Details
Human Rabbit Un-conjugated EIA, FACS, WB Flow cytometric analysis of A549 cells using HIF2A / HIF2 alpha Antibody (N-term) Cat.-No AP51440PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of HIF2A / HIF2 alpha Antibody (N-term) in A549 cell line lysates (35ug/lane). This demonstrates the EPAS1 antibody detected the EPAS1 protein (arrow). 0.4 mL Login to see 6 to 8 Days
401,50
Details
Human Mouse Biotin WB, IHC, IHC (p) Staining of heart, cardiac myocytes using ABIN151063. 0.1 mL Login to see 9 to 11 Days
438,90
Details
Human Mouse HRP WB, IHC, IHC (p) Staining of heart, cardiac myocytes using ABIN151063. 0.1 mL Login to see 9 to 11 Days
450,45
Details
Human Mouse Un-conjugated FACS, IHC, IHC (p), WB 0.1 mL Login to see 9 to 11 Days
473,55
Details

EPAS1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Endothelial PAS Domain Protein 1 Antibodies

  1. ABIN250055 : Bernhardt, Wiesener, Weidemann, Schmitt, Weichert, Lechler, Campean, Ong, Willam, Gretz, Eckardt: Involvement of hypoxia-inducible transcription factors in polycystic kidney disease. in The American journal of pathology 2007 (PubMed)
    Show all 15 references for ABIN250055

  2. ABIN250056 : Harvey, Kind, Pantaleon, Armstrong, Thompson: Oxygen-regulated gene expression in bovine blastocysts. in Biology of reproduction 2004 (PubMed)
    Show all 15 references for ABIN250056

  3. ABIN151063 : Mekhail, Gunaratnam, Bonicalzi, Lee: HIF activation by pH-dependent nucleolar sequestration of VHL. in Nature cell biology 2004 (PubMed)
    Show all 15 references for ABIN151063

  4. ABIN863098 : Kim, Perera, Zhou, Carretero, Yeh, Heathcote, Jackson, Nikolinakos, Ospina, Naumov, Brandstetter, Weigman, Zaghlul, Hayes, Padera, Heymach, Kung, Sharpless, Kaelin, Wong: HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice. in The Journal of clinical investigation 2009 (PubMed)
    Show all 4 references for ABIN863098

  5. ABIN654664 : Bougatef, Menashi, Khayati, Naïmi, Porcher, Podgorniak, Millot, Janin, Calvo, Lebbé, Mourah: EMMPRIN promotes melanoma cells malignant properties through a HIF-2alpha mediated up-regulation of VEGF-receptor-2. in PLoS ONE 2010 (PubMed)
    Show all 2 references for ABIN654664

  6. ABIN658111 : Mowat, Luhmann, Smith, Lange, Duran, Harten, Shukla, Maxwell, Ali, Bainbridge: HIF-1alpha and HIF-2alpha are differentially activated in distinct cell populations in retinal ischaemia. in PLoS ONE 2010 (PubMed)
    Show all 2 references for ABIN658111

  7. ABIN952733 : Yi, Liang, Huerta-Sanchez, Jin, Cuo, Pool, Xu, Jiang, Vinckenbosch, Korneliussen, Zheng, Liu, He, Li, Luo, Nie, Wu, Zhao, Cao, Zou, Shan, Li, Yang, Asan, Ni, Tian, Xu, Liu, Jiang, Wu, Zhou, Tang, Qin, Wang, Feng, Li, Huasang, Luosang, Wang, Chen, Wang, Zh: Sequencing of 50 human exomes reveals adaptation to high altitude. in Science (New York, N.Y.) 2010 (PubMed)
    Show all 2 references for ABIN952733

  8. ABIN151064 : Grabmaier, A de Weijert, Verhaegh, Schalken, Oosterwijk: Strict regulation of CAIX(G250/MN) by HIF-1alpha in clear cell renal cell carcinoma. in Oncogene 2004 (PubMed)
    Show all 2 references for ABIN151064

  9. ABIN137697 : Catrina, Botusan, Rantanen, Catrina, Pyakurel, Savu, Axelson, Biberfeld, Poellinger, Brismar: Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I. in Clinical cancer research : an official journal of the American Association for Cancer Research 2006 (PubMed)

  10. ABIN486914 : Koizume, Yokota, Miyagi, Hirahara, Tsuchiya, Miyagi: Heterogeneity in binding and gene-expression regulation by HIF-2alpha. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against Endothelial PAS Domain Protein 1 Interaction Partners

Human Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. EPAS1 is a key factor in the EGFR (show EGFR Antibodies)-MET crosstalk.

  2. data suggest that targeting intestinal HIF-2alpha has a significant therapeutic potential in SCD (show SCD Antibodies) pathophysiology

  3. increased nuclear expression indicates unfavorable prognosis in renal cell carcinoma (show MOK Antibodies) patients [review]

  4. Data indicate that hypoxia-induced cysteine-proteases inhibitor SERPINB3 (show SERPINB3 Antibodies) up-regulation is dependent on hypoxia-inducible factor-2alpha (HIF-2alpha).

  5. activity of the mitochondrial anti-oxidant SOD2 (show SOD2 Antibodies) and its pro-catabolic transcription factor HIF-2alpha, suggesting that an improved understanding of physiologic triggers of chondrocyte metabolic flexibility may provide new insight into the etiology of OA.

  6. HIF-2alpha silencing in colon cancer cells altered the expression of the stem cell markers CD44 (show CD44 Antibodies), Oct4 (show POU5F1 Antibodies), and CD24 (show CD24 Antibodies) and of the differentiation marker CK20 (show KRT20 Antibodies) in the opposite direction as HIF-1alpha (show HIF1A Antibodies) silencing.

  7. KDM6B (show Kdm6b Antibodies) is a new hypoxia response gene regulated by HIF-2alpha

  8. results indicated that the association between HIF-2alpha expression and prognostic values in HCC (show FAM126A Antibodies) was inconspicuous, while the expression of HIF-2alpha was significantly associated with capsule infiltration, vein invasion, and histological grade

  9. results from this study demonstrate that hypoxia induces LIF (show LIF Antibodies) expression in human cancer cells mainly through HIF-2alpha

  10. GPX8 (show GPX8 Antibodies) is transcriptionally regulated by HIFalpha and modulates growth factor signaling in HeLa cells.

Mouse (Murine) Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. HIF2alpha has a cardiomyogenesis-promoting effect in embryonic stem cells via enhancing the activation of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway.

  2. data suggest that targeting intestinal HIF-2alpha has a significant therapeutic potential in SCD (show SCD Antibodies) pathophysiology

  3. these results suggest that PTEN (show PTEN Antibodies) is required for apoptosis-mediated cavitation during epithelial morphogenesis by regulating the expression of HIF-2alpha and Bnip3 (show BNIP3 Antibodies)

  4. details the importance of breast milk iron in neonatal development and uncovers an unexpected molecular mechanism for the regulation of nutritional status of breast milk through intestinal HIF-2alpha

  5. crystal structures for each of mouse HIF-2alpha-ARNT (show ARNT Antibodies) and HIF-1alpha (show HIF1A Antibodies)-ARNT (show ARNT Antibodies) heterodimers in states that include bound small molecules and their hypoxia response element

  6. Hif-2alpha activation augments peroxisome turnover by selective autophagy (pexophagy) and thereby changes lipid composition reminiscent of peroxisomal disorders.

  7. pivotal role in the pathogenesis of rheumatoid arthritis by regulating fibroblast-like synoviocyte functions, independent of HIF-1alpha (show HIF1A Antibodies)

  8. The PTEN (show PTEN Antibodies)/PI3K/AKT (show AKT1 Antibodies) signaling axis controls hypoxia-induced HIF1alpha (HIF1A (show HIF1A Antibodies)) and HIF2alpha (EPAS1) stability in macrophages.

  9. we showed that muscles did not require macrophagic hif1a (show HIF1A Antibodies) or hif2a to regenerate. These results indicate that macrophagic HIFs do not play a crucial role during skeletal muscle regeneration induced by sterile tissue damage.

  10. These results suggest that there is a compensatory pathway involving HIF-1alpha (show HIF1A Antibodies) that regulates the expression of some HIF-2alpha target genes.

Pig (Porcine) Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. immunostaining for HIF-1alpha (show HIF1A Antibodies) and HIF-2alpha was observed during endochondral ossification; only HIF-2alpha was present at sites of intramembranous ossification

Endothelial PAS Domain Protein 1 (EPAS1) Antigen Profile

Antigen Summary

This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.

Gene names and symbols associated with EPAS1

  • endothelial PAS domain protein 1 (EPAS1) antibody
  • endothelial PAS domain protein 1 (epas1) antibody
  • endothelial PAS domain protein 1 (Epas1) antibody
  • bhlhe73 antibody
  • ecyt4 antibody
  • EPAS antibody
  • EPAS-1 antibody
  • EPAS1 antibody
  • HIF-2alpha antibody
  • hif2 antibody
  • hif2a antibody
  • hif2alpha antibody
  • hlf antibody
  • HRF antibody
  • mop2 antibody
  • pasd2 antibody

Protein level used designations for EPAS1

endothelial PAS domain protein 1 , endothelial PAS domain-containing protein 1-like , EPAS-1 , HIF-1-alpha-like factor , HIF-1alpha-like factor , HIF-2-alpha , HIF2-alpha , PAS domain-containing protein 2 , basic-helix-loop-helix-PAS protein MOP2 , class E basic helix-loop-helix protein 73 , endothelial PAS domain-containing protein 1 , hypoxia-inducible factor 2 alpha , hypoxia-inducible factor 2-alpha , member of PAS protein 2 , HIF-related factor , HIF1 alpha-like factor , HIF1alpha-like factor , HLF (HIF1alpha-like factor) , Hif like protein , hypoxia inducible transcription factor 2alpha , mHLF , HIF-2 alpha , HIF2 alpha , hypoxia inducible factor 2, alpha subunit , hypoxia inducible factor 2a , HIF-2alpha

GENE ID SPECIES
459204 Pan troglodytes
714641 Macaca mulatta
100220014 Taeniopygia guttata
100396711 Callithrix jacchus
100439667 Pongo abelii
100543912 Meleagris gallopavo
100551891 Anolis carolinensis
100606638 Nomascus leucogenys
2034 Homo sapiens
13819 Mus musculus
29452 Rattus norvegicus
444145 Xenopus laevis
395596 Gallus gallus
474578 Canis lupus familiaris
100037272 Sus scrofa
282711 Bos taurus
100068622 Equus caballus
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