Endothelial PAS Domain Protein 1 (EPAS1) Antibody Abstract

EPAS1 encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. antibodies-online currently ships , Endothelial PAS Domain Protein 1 (EPAS1) Kits (12) and to destinations worldwide.

list all antibodies Gene Name GeneID UniProt
EPAS1 2034 Q99814
Anti-Mouse EPAS1 EPAS1 13819 P97481
Anti-Rat EPAS1 EPAS1 29452 Q9JHS1

Show Endothelial PAS Domain Protein 1 (EPAS1) Antigene Profile

How to order from antibodies-online
  • +1 404 474 4654
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Endothelial PAS Domain Protein 1 (EPAS1) Antibodies at antibodies-online.com

Showing 10 out of 134 Endothelial PAS Domain Protein 1 (EPAS1) Antibodies

ABIN Reactivity Host Conjugate Application Images Quantity Delivery Price Details
ABIN151064 Human Mouse Un-conjugated WB, ChIP, FACS, ICC, IF, IHC, IHC (p), IP 0.025 mL 9 to 11 Days
246.84 $
Details
ABIN151063 Human Mouse Un-conjugated WB, ChIP, FACS, ICC, IF, IHC, IHC (p), IP 0.1 mL 9 to 11 Days
450.12 $
Details
ABIN654664 Human Rabbit Un-conjugated WB, FACS 400 µL 2 to 3 Days
291.50 $
Details
ABIN658111 Human Rabbit Un-conjugated WB 400 µL 2 to 3 Days
291.50 $
Details
ABIN250055 Human Mouse Biotin WB, IHC, IHC (p) 0.1 mL 9 to 11 Days
595.32 $
Details
ABIN250056 Human Mouse HRP WB, IHC, IHC (p) 0.1 mL 9 to 11 Days
595.32 $
Details
ABIN486914 Mouse Rabbit Un-conjugated WB 50 µg 2 to 3 Days
289.00 $
Details
ABIN863098 Human Mouse Un-conjugated WB, IHC, ICC, IF 25 µg 3 to 4 Days
162.80 $
Details
ABIN249868 Fish Rabbit Biotin WB, IHC, IHC (p) 0.1 mL 9 to 11 Days
595.32 $
Details
ABIN137697 Human Mouse Un-conjugated FACS, IHC, IHC (p), WB   0.1 mL 9 to 11 Days
566.28 $
Details

EPAS1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
, , ,
,
, , ,
Mouse (Murine) , , , ,
, ,
,
, , ,
Rat (Rattus) , , , ,
,
,
, , ,

Top referenced Endothelial PAS Domain Protein 1 (EPAS1) Antibodies

  1. ABIN249868 : Alvarez-Tejado, Naranjo-Suarez, Jimuenez, Carrera, Landuazuri, del Peso: Hypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells: protective role in apoptosis. in The Journal of biological chemistry 2001 (PubMed)
    Show all 17 references for ABIN249868

  2. ABIN250056 : Bernhardt, Wiesener, Weidemann, Schmitt, Weichert, Lechler, Campean, Ong, Willam, Gretz, Eckardt: Involvement of hypoxia-inducible transcription factors in polycystic kidney disease. in The American journal of pathology 2007 (PubMed)
    Show all 15 references for ABIN250056

  3. ABIN250055 : Harvey, Kind, Pantaleon, Armstrong, Thompson: Oxygen-regulated gene expression in bovine blastocysts. in Biology of reproduction 2004 (PubMed)
    Show all 15 references for ABIN250055

More Antibodies against Endothelial PAS Domain Protein 1 (EPAS1) Interaction Partners

Human Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. HIF-1 (show HIF1A Antibodies) and HIF-2 specific gene activating functions respond differently to different stimuli.

  2. all classes of RNA are profoundly regulated by hypoxia and implicated HIF as a major direct regulator of both the non-coding and coding transcriptome, acting predominantly through release of pre-bound promoter-paused RNApol2.

  3. Hif-1alpha (show HIF1A Antibodies) and Hif-2alpha competitively bind to NICD (show NOTCH1 Antibodies).

  4. Ascorbate-induced up-regulation of cellular ferroportin (show SLC40A1 Antibodies) levels was associated with increased levels of the iron regulatory protein IRP2 (show IREB2 Antibodies), and the hypoxia-inducible factor HIF2alpha.

  5. Data indicate that the invasion potencies were decreased more in ZnSO4-treated cells than in control cells after siRNA-mediated knockdown of hypoxia-inducible factors HIF-1alpha (show HIF1A Antibodies) and/or HIF-2alpha.

  6. HIF-2alpha expression was positively correlated with the induction of hypoxic genes in hepatoma cells.

  7. All of the identified polycythemic subjects with HIF2A mutations show serum erythropoietin (show EPO Antibodies) in the normal range.

  8. Sox9 (show SOX9 Antibodies) is a downstream target of Hif2alpha in ovarian cancer cells.Hif-2alpha regulates TUBB3 (show TUBB3 Antibodies) gene expression and affects ovarian cancer aggressiveness.

  9. Endothelial PAS domain protein 1(EPAS1) chr2:46441523(hg18) polymorphism C is strongly associated with susceptibility to high altitude pulmonary edema in Han Chinese; EPAS1 chr2:46441523(hg18) polymorphism G is present at high frequency in Tibetans.

  10. Overexpression of HIF-2alpha, TWIST, and CXCR4 (show CXCR4 Antibodies) is associated with lymph node metastasis in papillary thyroid carcinoma.

Mouse (Murine) Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. inactivation of endothelial HIF-2alpha, but not endothelial HIF-1alpha (show HIF1A Antibodies), resulted in increased expression of renal injury markers and inflammatory cell infiltration in the postischemic kidney, which was reversed by blockade of VCAM1 (show VCAM1 Antibodies) and VLA4

  2. HIF-1alpha (show HIF1A Antibodies) and HIF-2alpha regulate eosinophil migration and asthma airway resistance in opposing ways.

  3. In proximal tubular cells, AGE-BSA stimulation elevated mainly HIF-1alpha (show HIF1A Antibodies) transcriptional activity and to a lesser extent HIF-2alpha.

  4. both HIF2alpha and ETS1 (show ETS1 Antibodies) are involved in the transcriptional regulation of Flvcr1a and that HIF2alpha is absolutely required for Flvcr1a induction upon hypoxia

  5. HIF2a signaling appears to be a central pathway in chromaffin cell development and differentiation, with cells highly expressing HIF2a exhibiting a less differentiated and more stem cell-like phenotype.

  6. HIF-1alpha (show HIF1A Antibodies) and HIF-2alpha are involved in hypoxia-induced lipid accumulation in hepatocytes via reducing PGC-1alpha (show PPARGC1A Antibodies) mediated fatty acid beta-oxidation.

  7. ption of Vhl (show VHL Antibodies) led to a HIF-2alpha-dependent decrease in cholesterol hydroxylases involved in the conversion of cholesterol to bile acids.

  8. Significant accumulation of hypoxia-inducible factors 1alpha and 2alpha (HIF-1alpha (show HIF1A Antibodies) and HIF-2alpha).

  9. Manipulating or reducing the HIF-2alpha response in keratinocytes could be a useful means to accelerate wound healing and tissue repair.

  10. HIF-2alpha has a role in persistence of neutrophilic inflammation in humans, mice and zebrafish

Endothelial PAS Domain Protein 1 (EPAS1) Antigen Profile

Gene names and symbols associated with EPAS1

endothelial PAS domain protein 1 (EPAS1) , endothelial PAS domain protein 1 (epas1) , endothelial PAS domain protein 1 (Epas1)

EPAS1 , ECYT4 , HIF2A , HLF , MOP2 , PASD2 , bHLHe73 , HIF-2alpha , HRF , Hif2a , bhlhe73 , ecyt4 , hif2 , hif2a , hif2alpha , hlf , mop2 , pasd2 , EPAS , EPAS-1

Protein level used designations for EPAS1

endothelial PAS domain protein 1 , endothelial PAS domain-containing protein 1-like , EPAS-1 , HIF-1-alpha-like factor , HIF-1alpha-like factor , HIF-2-alpha , HIF2-alpha , PAS domain-containing protein 2 , basic-helix-loop-helix-PAS protein MOP2 , class E basic helix-loop-helix protein 73 , endothelial PAS domain-containing protein 1 , hypoxia-inducible factor 2 alpha , hypoxia-inducible factor 2-alpha , member of PAS protein 2 , HIF-related factor , HIF1 alpha-like factor , HIF1alpha-like factor , HLF (HIF1alpha-like factor) , Hif like protein , hypoxia inducible transcription factor 2alpha , mHLF , HIF-2 alpha , HIF2 alpha , hypoxia inducible factor 2, alpha subunit , hypoxia inducible factor 2a , HIF-2alpha

Antigen Summary

This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.

GENE ID SPECIES
459204 Pan troglodytes
714641 Macaca mulatta
100220014 Taeniopygia guttata
100396711 Callithrix jacchus
100439667 Pongo abelii
100543912 Meleagris gallopavo
100551891 Anolis carolinensis
100606638 Nomascus leucogenys
2034 Homo sapiens
13819 Mus musculus
29452 Rattus norvegicus
444145 Xenopus laevis
395596 Gallus gallus
474578 Canis lupus familiaris
100037272 Sus scrofa
282711 Bos taurus
100068622 Equus caballus
Selected quality suppliers for Endothelial PAS Domain Protein 1 (EPAS1) Antibodies
Did you look for something else?
back to top