Endothelial PAS Domain Protein 1 (EPAS1) Antibody Abstract

EPAS1 encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. antibodies-online currently ships , and Endothelial PAS Domain Protein 1 (EPAS1) Kits (12) to destinations worldwide.

list all antibodies Gene Name GeneID UniProt
EPAS1 2034 Q99814
EPAS1  
EPAS1  

Show Endothelial PAS Domain Protein 1 (EPAS1) Antigene Profile

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Top Endothelial PAS Domain Protein 1 (EPAS1) Antibodies at antibodies-online.com

Showing 12 out of 95 Endothelial PAS Domain Protein 1 (EPAS1) Antibodies

ABIN Reactivity Host Conjugate Application Quantity Delivery Validation Price Details
ABIN486914 Mouse Rabbit Un-conjugated WB 50 µg 2 to 3 days Data Validation Level 5/5
289.00 $
Details
ABIN654664 Human Rabbit Un-conjugated WB, FACS 400 µL 2 to 3 days Data Validation Level 5/5
291.50 $
Details
ABIN658111 Human Rabbit Un-conjugated WB 400 µL 2 to 3 days Data Validation Level 5/5
291.50 $
Details
ABIN863098 Human Mouse Un-conjugated WB, IHC, ICC, IF 25 µg 3 to 4 days Data Validation Level 4/5
162.80 $
Details
ABIN1742588 Human Mouse Un-conjugated IHC (fro), IHC (p), WB 0.1 mL 5 to 6 days Data Validation Level 4/5
576.05 $
Details
ABIN952733 Human Rabbit Un-conjugated FACS, WB 0.4 mL 6 to 8 days Data Validation Level 4/5
357.50 $
Details
ABIN1491582 Human Mouse Un-conjugated ICC, IHC (p), WB 25 µg 8 to 10 days Data Validation Level 4/5
434.50 $
Details
ABIN137697 Human Mouse Un-conjugated IHC (p), WB 0.1 mL 9 to 11 days Data Validation Level 4/5
566.28 $
Details
ABIN467734 Human Rabbit Un-conjugated WB 50 µg 8 to 10 days Data Validation Level 4/5
535.33 $
Details
ABIN958111 Human Goat Un-conjugated IHC (fro), WB 100 µg 8 to 10 days Data Validation Level 4/5
579.33 $
Details
ABIN574148 Human Rabbit Un-conjugated ICC, IF, IHC (p), WB 50 µL 8 to 10 days Data Validation Level 4/5
434.50 $
Details
ABIN686662 Human Rabbit Un-conjugated WB, IHC (p) 100 µL 2 to 3 days Data Validation Level 3/5
242.00 $
Details

EPAS1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Top referenced Endothelial PAS Domain Protein 1 (EPAS1) Antibodies

  1. ABIN863099 : Kim, Perera, Zhou, Carretero, Yeh, Heathcote, Jackson, Nikolinakos, Ospina, Naumov, Brandstetter, Weigman, Zaghlul, Hayes, Padera, Heymach, Kung, Sharpless, Kaelin, Wong: HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice. in The Journal of clinical investigation 2009 (PubMed)
    Show all 3 references for ABIN863099

  2. ABIN863098 : Favier, Lapointe, Maliba, Sirois: HIF2 alpha reduces growth rate but promotes angiogenesis in a mouse model of neuroblastoma. in BMC cancer 2007 (PubMed)
    Show all 3 references for ABIN863098

  3. ABIN952733 : Yi, Liang, Huerta-Sanchez, Jin, Cuo, Pool, Xu, Jiang, Vinckenbosch, Korneliussen, Zheng, Liu, He, Li, Luo, Nie, Wu, Zhao, Cao, Zou, Shan, Li, Yang, Asan, Ni, Tian, Xu, Liu, Jiang, Wu, Zhou, Tang, Qin, Wang, Feng, Li, Huasang, Luosang, Wang, Chen, Wang, Zh: Sequencing of 50 human exomes reveals adaptation to high altitude. in Science (New York, N.Y.) 2010 (PubMed)
    Show all 2 references for ABIN952733

ABIN486914 WB Suggested Anti-EPAS1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... (ABIN486914)
ABIN654664 EPAS1 Antibody (N-term) (ABIN654664) western blot analysis in A549 cel... (ABIN654664)
ABIN658111 EPAS1 Antibody (C-term) (ABIN658111) western blot analysis in human pl... (ABIN658111)
ABIN863098 Hif2alpha Western Blotting CoCl treated Hela 20ug 1 in 1000. (ABIN863098)
ABIN863099 Hif2alpha Western Blotting CoCl treated Hela 20ug 1 in 1000. (ABIN863099)
ABIN574148 Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) (ABIN574148)
ABIN686662 Formalin-fixed and paraffin embedded human kidney cancer labeled with ... (ABIN686662)

More Antibodies against Endothelial PAS Domain Protein 1 (EPAS1) Interaction Partners

Human Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. IL-6 and IL-8 (show IL8 Antibodies) are HIF2alpha controlled cytokines for angiogenesis particularly in endothelial cells.

  2. This is the first report of a germline gain-of-function EPAS1/HIF2A mutation associated with congenital polycythemia that is also associated with multiple PGL tumors.

  3. A model in which the sustained synthesis of VEGF (show VEGFA Antibodies) in lens epithelial cells, maintained under hypoxic condition, is regulated by a compensatory inter-relationship between HIF-1alpha and HIF-2alpha

  4. Knockdown of HIF-2alpha and HIF-1alpha mRNA in pulmonary vascular endothelial cells decreased cell proliferation under normoxic as well as hypoxic conditions.

  5. study demonstrates that mTORC2 (show CRTC2 Antibodies) complex stability and activation is redox sensitive, and further defined a novel role for p22(phox (show CYBA Antibodies))-based Nox oxidases in eIF4E (show EIF4E Antibodies)-dependent mRNA translation through mTORC2 (show CRTC2 Antibodies)

  6. Data indicate that the new HIF2alpha partners microphthalmia-associated transcription factor, SOX10 (show SOX10 Antibodies), and AP2alpha (show AP2A1 Antibodies), which are master actors of melanoma development, were confirmed via co-immunoprecipitation experiments.

  7. Our results suggest that HIF-2alpha may represent a more aggressive phenotype in small cell lung cancer

  8. HIF2A and IGF2 expression correlates in human neuroblastoma cells and normal immature sympathetic neuroblasts.

  9. Expression of HIF-2a Is Sufficient to Induce Reductive Carboxylation and Lipogenesis from Glutamine in renal cell carcinoma cells.

  10. HIF1alpha and HIF2alpha activate independent transcriptional programs through SRC that promote metastasis by coordinately regulating cell invasion and ECM remodeling

Endothelial PAS Domain Protein 1 (EPAS1) Antigene Profile

Gene names and symbols associated with EPAS1

endothelial PAS domain protein 1 (EPAS1) , endothelial PAS domain protein 1 (epas1)

HLF , MOP2 , ECYT4 , HIF2A , PASD2 , bHLHe73 , EPAS , EPAS-1 , bhlhe73 , ecyt4 , hif2 , hif2a , hif2alpha , hlf , mop2 , pasd2 , EPAS1

Protein level used designations for EPAS1

EPAS-1 , HIF-1-alpha-like factor , HIF-1alpha-like factor , HIF-2-alpha , HIF2-alpha , PAS domain-containing protein 2 , basic-helix-loop-helix-PAS protein MOP2 , class E basic helix-loop-helix protein 73 , endothelial PAS domain-containing protein 1 , hypoxia-inducible factor 2 alpha , hypoxia-inducible factor 2-alpha , member of PAS protein 2 , HIF-2alpha , endothelial PAS domain protein 1 , endothelial PAS domain-containing protein 1-like

Antigene Summary

This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.

GENE ID SPECIES
2034 Homo sapiens
282711 Bos taurus
395596 Gallus gallus
474578 Canis lupus familiaris
100037272 Sus scrofa
444145 Xenopus laevis
459204 Pan troglodytes
714641 Macaca mulatta
100220014 Taeniopygia guttata
100396711 Callithrix jacchus
100439667 Pongo abelii
100543912 Meleagris gallopavo
100551891 Anolis carolinensis
100606638 Nomascus leucogenys
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