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Endothelin Converting Enzyme 2 Proteins (ECE2)

Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family (Lorenzo et al., 2001 [PubMed 11718899]).[supplied by OMIM, Mar 2008].. Additionally we are shipping ECE2 Antibodies (35) and ECE2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ECE2 9718 O60344
ECE2 107522 Q80Z60
Rat ECE2 ECE2 408243  
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Top ECE2 Proteins at antibodies-online.com

Showing 6 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human Fc Tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

ECE2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine) ,
,

Top referenced ECE2 Proteins

  1. Human ECE2 Protein expressed in Human Cells - ABIN2002346 : Emoto, Yanagisawa: Endothelin-converting enzyme-2 is a membrane-bound, phosphoramidon-sensitive metalloprotease with acidic pH optimum. in The Journal of biological chemistry 1995 (PubMed)
    Show all 3 references for ABIN2002346

More Proteins for Endothelin Converting Enzyme 2 (ECE2) Interaction Partners

Human Endothelin Converting Enzyme 2 (ECE2) interaction partners

  1. Te results of this study suggested taht genetic variations in MMEL1 (show MMEL1 Proteins), ECE1 (show ECE1 Proteins), ECE2, AGER (show AGER Proteins), PLG (show PLG Proteins), PLAT (show PLAT Proteins), NR1H3 (show NR1H3 Proteins), MMP3 (show MMP3 Proteins), LRP1 (show LRP1 Proteins), TTR (show TTR Proteins), NR1H2 (show NR1H2 Proteins), and MMP9 (show MMP9 Proteins) genes do not play major role among the Finnish AD patient cohort.

  2. The PL405 assay is thus the first tool to study ECE-2 inhibition using high throughput screening or for ex vivo ECE-2 quantification.

  3. Data show that CD133 and ECE (show ECE1 Proteins) expressions are associated with lymphoid metastasis and prognosis of NSCLC, and their overexpression often suggests unfavorable prognosis of NSCLC.

  4. The most significantly downregulated gene in this data set was the endothelin converting enzyme 2 (ECE2), implicated in amyloid beta clearance.

  5. An intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 gene

  6. Abeta (show APP Proteins) accumulation in Alzheimer's disease is unlikely to be caused by ECE-2 deficiency. However, ECE-2 expression is up-regulated

Mouse (Murine) Endothelin Converting Enzyme 2 (ECE2) interaction partners

  1. These results suggest that ECE2, by selectively processing endogenous opioid peptides in the endocytic compartment, plays a role in modulating opioid receptor activity

  2. a role for differential modulation of opioid receptor signaling by post-endocytic processing of peptide agonists by ECE2.

  3. ECE-2 has a role in the non-classical processing of spinal cord peptides and morphine responses, including the cleavage of a number of neuropeptides at non-classical sites in vitro.

  4. deficits in learning and memory in ECE2 knockout mice may provide unique insights into processes that may contribute to this disease and possible other disorders of cognition

  5. The PL405 assay is thus the first tool to study ECE-2 inhibition using high throughput screening or for ex vivo ECE-2 quantification.

  6. novel four subisoforms of ECE-2 that differ in their N-terminal cytoplasmic tails

  7. ECE2 has a role in limiting Abeta (show APP Proteins) accumulation in the mouse brain

ECE2 Protein Profile

Protein Summary

Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family (Lorenzo et al., 2001

Gene names and symbols associated with ECE2

  • endothelin converting enzyme 2 (ECE2)
  • endothelin converting enzyme 2 (ece2)
  • endothelin converting enzyme 2 (Ece2)
  • endothelin-converting enzyme 2 (Ece2)
  • 1810009K13Rik protein
  • 6330509A19Rik protein
  • 9630025D12Rik protein
  • BB127715 protein
  • ECE2 protein

Protein level used designations for ECE2

endothelin converting enzyme 2 , endothelin-converting enzyme 2 , ECE-2 , endothelin-converting enzyme 2 isoform 2a-1 , endothelin-converting enzyme 2 isoform 2a-2 , endothelin-converting enzyme 2 isoform 2b-1 , endothelin-converting enzyme 2 isoform 2b-2

GENE ID SPECIES
471026 Pan troglodytes
488105 Canis lupus familiaris
702851 Macaca mulatta
100059042 Equus caballus
100348333 Oryctolagus cuniculus
100471173 Ailuropoda melanoleuca
100488407 Xenopus (Silurana) tropicalis
100543478 Meleagris gallopavo
100561383 Anolis carolinensis
100579440 Nomascus leucogenys
100617062 Monodelphis domestica
100627224 Sus scrofa
9718 Homo sapiens
107522 Mus musculus
281134 Bos taurus
408243 Rattus norvegicus
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