You are viewing an incomplete version of our website. Please click to reload the website as full version.

Engrailed Homeobox 2 Proteins (EN2)

Homeobox-containing genes are thought to have a role in controlling development. Additionally we are shipping EN2 Antibodies (80) and EN2 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EN2 13799 P09066
EN2 2020 P19622
Rat EN2 EN2 499964  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top EN2 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag,S tag 50 μg Log in to see 9 to 11 Days
$418.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

EN2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

More Proteins for Engrailed Homeobox 2 (EN2) Interaction Partners

Mouse (Murine) Engrailed Homeobox 2 (EN2) interaction partners

  1. En2 deletion reduces monoamine innervation of target forebrain structures, affecting forebrain structural growth, postnatal neurogenesis and related behavior.

  2. confirm the early neurotransmitter deficit with a late compensatory recovery in En2 KO-mice further suggesting that this experimental animal may be considered a good predictive model for the human disease

  3. The homeoprotein Engrailed is not only a survival factor for mesencephalic dopaminergic (mDA) neurons during development, but continues to exert neuroprotective and physiological functions in adult mDA neurons. [Review]

  4. En2-/- hippocampus, neurofibromin (show NF1 Proteins)-dependent pathways converging on SynI (show SYN1 Proteins) phosphorylation might underlie hippocampal-dependent learning deficits observed in En2-/- mice.

  5. This study demonistrated that engrailed 2 knock-out mice show impaired spatial learning with hippocampal dysreulation.

  6. EN2 levels are increased in affected individuals with an A-C/G-T genotype, supporting EN2 as an autism spectrum disorder susceptibility gene.

  7. This study showed that the Engrailed proteins are present in postnatal GABAergic neurons of the mouse hippocampus and cerebral cortex, and adult En2(-/-) mice show reduced expression of GABAergic marker mRNAs in these areas.

  8. En1 (show EN1 Proteins) is the predominant functional En paralog in maturing 5-HT (show DDC Proteins) neurons, although a small contribution from En2 was reproducibly detected

  9. En1 (show EN1 Proteins) and En2 act together in multiple cerebellar cell types to determine overall growth and formation of particular fissures.

  10. This study characterized En1 (show EN1 Proteins) and En2 expression around birth and at postnatal day (P) 21 during the period when the cerebellum undergoes a remarkable transformation from a smooth ovoid structure to a highly foliated structure.

Human Engrailed Homeobox 2 (EN2) interaction partners

  1. EN2 may be a candidate oncogene in bladder cancer by activating the PI3K/Akt pathway and inhibiting PTEN.

  2. Engrailed-2 (EN-2) is a developmentally regulated homeobox (show Lbx1 Proteins) gene that is essential for Purkinje cell maturation and normal cerebellar development and patterning.

  3. The mean EN2 levels in prostate cancer patients were 3.76-fold higher than those in non-prostate patients after prostate massage.

  4. The exact role of EN2 expression in renal carcinoma carcinogenesis requires further investigation.

  5. En2 identified as a new regulator of T-cell differentiation whose disruption induces a malignant T-cell fate in chronic myelogenous leukemia progression.

  6. Two patients with underdeveloped arcuate fasciculus had novel, nonsynonymous variants in MID1 (show MID1 Proteins) and EN2 genes regulating axon guidance pathway.

  7. EN2 levels are increased in affected individuals with an A-C/G-T genotype, supporting EN2 as an autism spectrum disorder susceptibility gene.

  8. urinary EN2 has the potential to be a more sensitive and specific protein biomarker for non-muscle-invasive bladder cancer than currently available tests.

  9. Urinary EN2 may be useful as a non-invasive early biomarker for prostate cancer detection in genetically high-risk individuals

  10. Normal EN-2 downregulation may not occur in some individuals with autism, such that the postnatal persistence of EN-2 overexpression may contribute to autism cerebellar abnormalities.

EN2 Protein Profile

Protein Summary

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.

Gene names and symbols associated with Engrailed Homeobox 2 Proteins (EN2)

  • engrailed homeobox 2 (EN2)
  • engrailed homeobox (en)
  • engrailed 2 (En2)
  • engrailed homeobox 2 (En2)
  • engrailed homeobox 2 (LOC100859435)
  • BB131122 protein
  • en protein
  • En-2 protein
  • en2 protein
  • Gg-En-2 protein
  • RGD1561842 protein

Protein level used designations for Engrailed Homeobox 2 Proteins (EN2)

engrailed homeobox 2 , engrailed 2 , engrailed homolog 2 , engrailed homeobox , homeobox protein en-2 , homeobox protein engrailed-2 , mo-En-2 , engrailed-2 , hu-En-2

GENE ID SPECIES
280783 Bos taurus
716307 Macaca mulatta
742707 Pan troglodytes
100303466 Saccoglossus kowalevskii
13799 Mus musculus
2020 Homo sapiens
499964 Rattus norvegicus
100859435 Gallus gallus
Selected quality suppliers for EN2 Proteins (EN2)
Did you look for something else?