You are viewing an incomplete version of our website. Please click to reload the website as full version.

Engulfment and Cell Motility 1 Proteins (ELMO1)

ELMO1 encodes a member of the engulfment and cell motility protein family. Additionally we are shipping ELMO1 Antibodies (65) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ELMO1 9844 Q92556
ELMO1 140580 Q8BPU7
Rat ELMO1 ELMO1 361251  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top ELMO1 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ELMO1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Engulfment and Cell Motility 1 (ELMO1) Interaction Partners

Xenopus laevis Engulfment and Cell Motility 1 (ELMO1) interaction partners

  1. ELMO-DOCK1 (show DOCK1 Proteins), a bipartite guanine nucleotide exchange factor (show ARHGEF12 Proteins) complex for the small GTPase (show RACGAP1 Proteins) Rac1, and for the membrane-cytoskeletal linker Ezrin (show EZR Proteins), regulates centriole/basal body migration, docking and spacing.

Human Engulfment and Cell Motility 1 (ELMO1) interaction partners

  1. ELMO1 is expressed in rheumatoid arthritis synovium, promotes cell migration and invasion, and regulates Rac1 activity, thereby mediating rheumatoid arthritis pathogenicity.

  2. Src-mediated Y724 phosphorylation in ELMO1 plays a critical role for cell spreading via activation of Rac1, leading to promotion of cell migration.

  3. high ELMO1 expression is an independent negative prognostic factor in normal karyotype (NK) acute myeloid leukemia (show BCL11A Proteins).

  4. For ELMO1 (+9170 G>A), the GG genotype frequency was higher in the diabetic versus control group, but there were no differences between diabetic patients with and without nephropathies.

  5. Thus, Elmo1 and Dock180 (show DOCK1 Proteins) facilitate blood vessel formation by stabilization of the endothelium during angiogenesis.

  6. There is a low frequency rate of the ancestral genotype for the ELMO1 polymorphism rs1345365 in mestizos from the western and southeastern regions of Mexico.

  7. High ELMO1 expression is associated with serous ovarian cancer.

  8. the present study characterized a novel Nck-1-ELMO1 interaction and defined a new role for Nck-1 in regulating Rac1 activity.

  9. findings reveal a previously unknown, nonredundant role for Elmo1 in controlling Dock2 levels and Dock2-dependent T cell migration in primary lymphocytes.

  10. genetic association study in population in China: Data suggest that 2 SNPs in ELMO1 (rs741301; rs10951509) are associated with diabetic nephropathy in Chinese subjects with type 2 diabetes.

Mouse (Murine) Engulfment and Cell Motility 1 (ELMO1) interaction partners

  1. Elmo1 hypermorphs have albuminuria, glomerulosclerosis, and changes in the ultrastructure of the glomerular basement membrane that increase in severity in parallel with the expression of Elmo 1.

  2. Src contributed to tyrosine phosphorylation of ELMO1 at Y720 and Y724 residues, which was crucial for activation of Rac1, followed by the promoting cell adhesion, spreading, and migration.

  3. findings reveal a previously unknown, nonredundant role for Elmo1 in controlling Dock2 levels and Dock2-dependent T cell migration in primary lymphocytes.

  4. regulator of Med31 (show MED31 Proteins), revealing a previously unrecognized link between cytoplasmic signaling proteins and the Mediator complex

  5. Data show that intracellular engulfment protein ELMO1 was required for phagocytosis by DCX (show DCX Proteins)(+) cells.

  6. findings uncover a selective requirement for ELMO1 in Sertoli-cell-mediated removal of apoptotic germ cells and make a compelling case for a relationship between engulfment and tissue homeostasis in vivo

  7. functional studies suggest that BAI1 (show BAI1 Proteins) cooperates with ELMO/Dock180 (show DOCK1 Proteins)/Rac (show AKT1 Proteins) to promote maximal engulfment of apoptotic cells

Zebrafish Engulfment and Cell Motility 1 (ELMO1) interaction partners

  1. ELMO-DOCK1 (show DOCK1 Proteins), a bipartite guanine nucleotide exchange factor (show ARHGEF12 Proteins) complex for the small GTPase (show RACGAP1 Proteins) Rac1, and for the membrane-cytoskeletal linker Ezrin (show EZR Proteins), regulates centriole/basal body migration, docking and spacing.

  2. A novel signaling cascade is identified in which ELMO1/DOCK180 (show DOCK1 Proteins) regulates vasculature formation in zebrafish.

ELMO1 Protein Profile

Protein Summary

This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with ELMO1

  • engulfment and cell motility 1 (ELMO1)
  • engulfment and cell motility 1 (elmo1)
  • engulfment and cell motility 1 (Elmo1)
  • engulfment and cell motility 1 (ced-12 homolog, C. elegans) (elmo1)
  • 6330578D22Rik protein
  • C230095H21Rik protein
  • CED-12 protein
  • CED12 protein
  • ELMO-1 protein
  • ELMO1 protein
  • ELMO1s protein
  • im:7151147 protein
  • MGC68475 protein
  • wu:fq24e08 protein
  • zgc:85612 protein

Protein level used designations for ELMO1

Protein ced-12-like protein , engulfment and cell motility protein 1 , engulfment and cell motility 1 , engulfment and cell motility protein 1-like , ced-12 homolog 1 , engulfment and cell motility 1, ced-12 homolog , engulfment and cell motility 1 splice 1

GENE ID SPECIES
705818 Macaca mulatta
100055551 Equus caballus
100388716 Callithrix jacchus
100473639 Ailuropoda melanoleuca
398953 Xenopus laevis
463354 Pan troglodytes
100172678 Pongo abelii
100522109 Sus scrofa
100549625 Meleagris gallopavo
100554558 Anolis carolinensis
100586402 Nomascus leucogenys
9844 Homo sapiens
509821 Bos taurus
612913 Canis lupus familiaris
140580 Mus musculus
361251 Rattus norvegicus
420735 Gallus gallus
406364 Danio rerio
Selected quality suppliers for ELMO1 Proteins (ELMO1)
Did you look for something else?