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EBI3 was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. Additionally we are shipping EBI3 Proteins (27) and EBI3 Kits (10) and many more products for this protein.
Showing 10 out of 114 products:
Human Monoclonal EBI3 Primary Antibody for ELISA - ABIN394997
Kempe, Heinz, Kokai, Devergne, Marx, Wirth: Epstein-barr virus-induced gene-3 is expressed in human atheroma plaques. in The American journal of pathology 2009
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Human Polyclonal EBI3 Primary Antibody for WB - ABIN1881277
Krumbiegel, Anthogalidis-Voss, Markus, Zepp, Meyer: Enhanced expression of IL-27 mRNA in human newborns. in Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2008
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Human Polyclonal EBI3 Primary Antibody for EIA, IHC (p) - ABIN499778
Pflanz, Timans, Cheung, Rosales, Kanzler, Gilbert, Hibbert, Churakova, Travis, Vaisberg, Blumenschein, Mattson, Wagner, To, Zurawski, McClanahan, Gorman, Bazan, de Waal Malefyt, Rennick, Kastelein: IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. in Immunity 2002
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Human Polyclonal EBI3 Primary Antibody for EIA, IHC (p) - ABIN499776
Niedbala, Wei, Cai, Hueber, Leung, McInnes, Liew: IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells. in European journal of immunology 2007
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IL-35 was elevated in bone marrow of adult AML (show RUNX1 Antibodies) patients and this increase was correlated with the clinical stages of malignancy, suggesting that IL-35 is involved in pathogenesis of AML (show RUNX1 Antibodies).
Data suggest that the toll like receptor 3 (TLR3 (show TLR3 Antibodies))-interferon regulatory factor 6 (show IRF6 Antibodies) protein (IRF6 (show IRF6 Antibodies))-interleukin-23 subunit p19 (p19 (show IL23A Antibodies))/EBI3 protein axis may regulate keratinocyte functions in the skin.
EBI3 gene rs4740 polymorphism is closely associated wit (show SLC11A1 Antibodies)h susceptibility to pulmonary tuberculosis and the elevation and enrichment of EBI3 in the lung derived from macrophages may contribute to the exacerbation of mycobacterial infection.
EBI3 Downregulation Contributes to Type I Collagen Overexpression in Scleroderma Skin.
IL-35 can effectively suppress the proliferation and IL-4 (show IL4 Antibodies) production of activated CD4 (show CD4 Antibodies)+CD25 (show IL2RA Antibodies)- T cells in allergic asthma, and that IL-35 may be a new immunotherapy for asthma patients.
IL-35 is highly expressed in chronic HBV CD4 (show CD4 Antibodies)(+) T-cells and plays an important role in the inhibition of the cellular immune response in chronic HBV.
The levels of EBI3 and IL-12p35 mRNAs in peripheral blood mononuclear cells in moderate or hyper-responders were significantly higher than those in non- or hypo-responders.
IL-17 (show IL17A Antibodies) and IL-35 may be critically involved in the pathogenesis of hepatitis B-related LC.
IL35 appears to contribute to the loss of immunological self-tolerance in ITP (show ITPA Antibodies) patients by modulating T cells and immunoregulatory cytokines.
Interleukin-35 induces regulatory B cells that suppress autoimmune disease. [il-35]
our results demonstrate that EBI3 is an essential general regulator of inflammatory immune responses in experimental Chagas disease
Report higher EBI3 expression in the lung tissue of BCG (show SLC11A1 Antibodies)-infected mice.
IL-35 subunits (p35 and EBI3) have the immunoregulatory role in systemic lupus erythematosus.
Lack of EBI3, p35 (show CDK5R1 Antibodies), and IL-12 (show IL12A Antibodies) receptor beta2 caused enhanced infiltration of lymphocytes into the testicular interstitium, with increased interferon-gamma (show IFNG Antibodies) expression in the testes and autoantibody production against mainly acrosomal regions of spermatids.
Data (including data from knockout mice) suggest Ebi3 (Epstein-Barr virus induced protein 3 (show HSPB3 Antibodies)) and IL12 (show IL12A Antibodies) (interleukin 12) down-regulate helper-inducer T-lymphocyte (Th17 cell) function in immune response to Listeria monocytogenes.
results indicate that EBI3 may be important in EAU initiation by Th1 (show HAND1 Antibodies) cell responses and may suppress experimental autoimmune uveitis by inhibition of both Th1 (show HAND1 Antibodies) and Th17 cell responses in the late/maintenance phase.
Anti-CD200R2 (show CD200R1L Antibodies), anti-IL-9 (show IL9 Antibodies), anti-IL-35, or anti-TGF-beta (show TGFB1 Antibodies) abolishes increased graft survival and Treg induction induced in cromolyn-treated CD200R1KO.CD200tg mice, and suggest combined role of mast cells and Tregs.
the findings from the past decade identify IL-27 (show IL27 Antibodies) as a critical immunoregulatory cytokine, especially for T cells, whereas some controversy is fueled by results challenging the view of IL-27 (show IL27 Antibodies) as a classical silencer of inflammation.
These data demonstrate a regulatory role for EBI3-associated cytokines in controlling host responses following CNS viral infection.
This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.
EBV-induced gene 3 protein
, Epstein-Barr virus induced gene 3
, IL-27 subunit beta
, IL27 subunit
, IL35 subunit
, cytokine receptor
, epstein-Barr virus-induced gene 3 protein
, interleukin-27 subunit beta
, Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor)
, epstein-Barr virus-induced gene 3 protein homolog