anti-Epstein-Barr Virus Induced 3 (EBI3) Antibodies

EBI3 was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. Additionally we are shipping EBI3 Proteins (32) and EBI3 Kits (16) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EBI3 10148 Q14213
EBI3 50498 O35228
EBI3 680609  
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Top anti-EBI3 Antibodies at antibodies-online.com

Showing 10 out of 129 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB <b>WB Suggested Anti-EBI3 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>U937 cell lysate WB Suggested Anti-EBI3 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: U937 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of IL-27B expression in HeLa (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged EBI3 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Allophycocyanin FACS Detection of IL-27/IL-35 EBI3 Subunit in KG-1 Human Cell Line by Flow Cytometry. KG-1 human acute myelogenous leukemia cell line was stained with Mouse Anti-Human IL-27/IL-35 EBI3 Subunit APC-conjugated Monoclonal Antibody. Detection of IL-27/IL-35 EBI3 Subunit in KG-1 Human Cell Line by Flow Cytometry. KG-1 human acute myelogenous leukemia cell line was stained with Mouse Anti-Human IL-27/IL-35 EBI3 Subunit APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$372.75
Details
Human Rabbit Un-conjugated WB Western blot analysis of EBI3 Antibody (C-term) Pab (ABIN1881277) pre-incubated without(lane 1) and with(lane 2) blocking peptide in 293 cell line lysate. EBI3 Antibody (C-term) (arrow) was detected using the purified Pab. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated CyTOF, FACS Detection of IL-27/IL-35 EBI3 Subunit in KG-1 Human Cell Line by Flow Cytometry. KG-1 human acute myelogenous leukemia cell line treated with 40 ng/mL Recombinant Human IL-18/IL-1F4. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. Detection of IL-27/IL-35 EBI3 Subunit in KG-1 Human Cell Line by Flow Cytometry. KG-1 human acute myelogenous leukemia cell line treated with 40 ng/mL Recombinant Human IL-18/IL-1F4. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. 100 μg Log in to see 8 to 9 Days
$267.75
Details
Human Goat Un-conjugated ELISA   0.1 mg Log in to see 7 to 9 Days
$317.63
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 100 μg Log in to see 7 to 9 Days
$537.17
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 7 to 9 Days
$537.17
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details

EBI3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-EBI3 Antibodies

  1. Human Polyclonal EBI3 Primary Antibody for WB - ABIN1881277 : Kempe, Heinz, Kokai, Devergne, Marx, Wirth: Epstein-barr virus-induced gene-3 is expressed in human atheroma plaques. in The American journal of pathology 2009 (PubMed)
    Show all 5 Pubmed References

  2. Human Monoclonal EBI3 Primary Antibody for FACS - ABIN4896337 : Long, Zhang, Wen, Kong, Lv, An, Wei: IL-35 over-expression increases apoptosis sensitivity and suppresses cell growth in human cancer cells. in Biochemical and biophysical research communications 2013 (PubMed)

  3. Human Polyclonal EBI3 Primary Antibody for ELISA - ABIN449841 : Collison, Workman, Kuo, Boyd, Wang, Vignali, Cross, Sehy, Blumberg, Vignali: The inhibitory cytokine IL-35 contributes to regulatory T-cell function. in Nature 2007 (PubMed)

More Antibodies against EBI3 Interaction Partners

Human Epstein-Barr Virus Induced 3 (EBI3) interaction partners

  1. The plasma levels of interleukin-35 were significantly higher in the hepatocellular carcinoma patients than the controls.

  2. over-expression of EBI3 could reduce the apoptosis of Treg/CD4 (show CD4 Antibodies)(+)T/CD8 (show CD8A Antibodies)(+)T cells and prevent radiation-induced immunosuppression of cervical cancer HeLa cells by inhibiting the activation of PD-1 (show PDCD1 Antibodies)/PD-L1 (show CD274 Antibodies) signaling pathway

  3. Data show that interleukin-35 (Epstein-Barr virus-induced gene 3 (EBI3) and the interleukin-12 Subunit p35 (p35) subunit) levels were significantly elevated in the patients with influenza infection.

  4. IL-35 was elevated in bone marrow of adult AML (show RUNX1 Antibodies) patients and this increase was correlated with the clinical stages of malignancy, suggesting that IL-35 is involved in pathogenesis of AML (show RUNX1 Antibodies).

  5. Data suggest that the toll like receptor 3 (TLR3 (show TLR3 Antibodies))-interferon regulatory factor 6 (show IRF6 Antibodies) protein (IRF6 (show IRF6 Antibodies))-interleukin-23 subunit p19 (p19 (show IL23A Antibodies))/EBI3 protein axis may regulate keratinocyte functions in the skin.

  6. EBI3 gene rs4740 polymorphism is closely associated wit (show SLC11A1 Antibodies)h susceptibility to pulmonary tuberculosis and the elevation and enrichment of EBI3 in the lung derived from macrophages may contribute to the exacerbation of mycobacterial infection.

  7. EBI3 Downregulation Contributes to Type I Collagen Overexpression in Scleroderma Skin.

  8. IL-35 can effectively suppress the proliferation and IL-4 (show IL4 Antibodies) production of activated CD4 (show CD4 Antibodies)+CD25 (show IL2RA Antibodies)- T cells in allergic asthma, and that IL-35 may be a new immunotherapy for asthma patients.

  9. IL-35 is highly expressed in chronic HBV CD4 (show CD4 Antibodies)(+) T-cells and plays an important role in the inhibition of the cellular immune response in chronic HBV.

  10. The levels of EBI3 and IL-12p35 mRNAs in peripheral blood mononuclear cells in moderate or hyper-responders were significantly higher than those in non- or hypo-responders.

Mouse (Murine) Epstein-Barr Virus Induced 3 (EBI3) interaction partners

  1. IL-35-transduced adipocyte-derived mesenchymal stem cells in vivo can enhance proliferation of CD4 (show CD4 Antibodies)(+) CD25 (show IL2RA Antibodies)(+) Treg cells and suppress the function of effector T cells such as T helper (Th) 1 (show TH1L Antibodies), Th2 and Th17 cells and may reduce the development of allograft rejection.

  2. we describe here a new IL-12 member IL-39 (IL-23p19/Ebi3) secreted by activated B cells that mediate inflammatory responses in lupus-like mice. Thus, IL-39 might contribute to immunopathogenic mechanisms of SLE.

  3. EBI3 can mediate IL-6 trans-signaling in a process that involves gp130

  4. Data show that interleukin-35 (Epstein-Barr virus-induced gene 3 (EBI3) and the interleukin-12 Subunit p35 (p35) subunit) expressing plasmid downregulates the expression of pro-inflammatory cytokines and upregulates the expression of anti-inflammatory cytokines.

  5. IL-35 treatment reduced collagen-induced arthritis via inhibiting vascular endothelial growth factor and its receptors

  6. Data suggest that interleukin-35 (Epstein-Barr virus-induced gene 3 (EBI3) and the interleukin-12 Subunit p35 (p35) subunit) contributes to the increased susceptibility to secondary pneumococcal pneumonia.

  7. our results demonstrate that EBI3 is an essential general regulator of inflammatory immune responses in experimental Chagas disease

  8. Report higher EBI3 expression in the lung tissue of BCG (show SLC11A1 Antibodies)-infected mice.

  9. EBI3 Downregulation Contributes to Type I Collagen Overexpression in Scleroderma Skin.

  10. IL-35 subunits (p35 and EBI3) have the immunoregulatory role in systemic lupus erythematosus.

EBI3 Antigen Profile

Protein Summary

This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.

Gene names and symbols associated with EBI3

  • Epstein-Barr virus induced 3 (EBI3) antibody
  • Epstein-Barr virus induced gene 3 (ebi3) antibody
  • Epstein-Barr virus induced gene 3 (Ebi3) antibody
  • Epstein-Barr virus induced 3 (Ebi3) antibody
  • EBI-3 antibody
  • EBI3 antibody
  • IL-27 antibody
  • IL-27B antibody
  • il-27rb antibody
  • IL27B antibody
  • si:dkey-97a13.4 antibody

Protein level used designations for EBI3

EBV-induced gene 3 protein , Epstein-Barr virus induced gene 3 , IL-27 subunit beta , IL27 subunit , IL35 subunit , cytokine receptor , epstein-Barr virus-induced gene 3 protein , interleukin-27 subunit beta , Epstein-Barr virus induced 3 , Il27rbeta , interleukin 27 receptor beta , IL-27B , epstein-Barr virus-induced gene 3 protein homolog , Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor)

GENE ID SPECIES
10148 Homo sapiens
485043 Canis lupus familiaris
514933 Bos taurus
737135 Pan troglodytes
100134974 Danio rerio
50498 Mus musculus
680609 Rattus norvegicus
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