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Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41) ELISA Kits

The protein encoded by EPB41, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. Additionally we are shipping Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) Antibodies (59) and Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
EPB41 2035 P11171
EPB41 269587 P48193
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Top Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) ELISA Kits at antibodies-online.com

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Human
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$480.00
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More ELISA Kits for Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) Interaction Partners

Zebrafish Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41) interaction partners

Human Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41) interaction partners

  1. The 4.1R, 4.1N (show EPB41L1 ELISA Kits) and 4.1B (show EPB41L3 ELISA Kits) are all expressed at the lateral membrane as well as cytoplasm of epithelial cells, suggesting a potentially redundant role of these proteins.

  2. Calcium mediates the conformation-based 4.1R FERM domain binding to membrane proteins by calmodulin (show CALM1 ELISA Kits).

  3. Results suggest a previously unidentified role for the scaffolding protein 4.1R in locally controlling CLASP2 behavior, CLASP2 cortical platform turnover and GSK3 activity, enabling correct MT organization and dynamics essential for cell polarity.

  4. We conclude that PIP2 may play an important role as a modulator of apo (show C9orf3 ELISA Kits)-CaM (show CALM1 ELISA Kits) binding to 4.1R(80) throughout evolution.

  5. Plasmodium falciparum PF3D7_0402000 was identified as a new binding partner for the major erythrocyte cytoskeletal protein (show ACTN1 ELISA Kits), 4.1R.

  6. a novel gene region, EPB41, which may be associated with smoking cessation, along with gene regions in CNR1 (show CNR1 ELISA Kits) that may be targeted to further elucidate the etiology of gender differences in smoking behaviors.

  7. 4.1R regulates NHE1 (show SLC9A1 ELISA Kits) activity through a direct protein-protein interaction that can be modulated by intracellular pH and Na(+) and Ca(2 (show CA2 ELISA Kits)+) concentrations.

  8. Further studies involving siRNA-mediated knockdowns of spectrin, adducin, or p4.1 revealed that those proteins are needed for efficient docking of enterohaemorrhagic Escherichia coli to host cells.

  9. This study characterizes the mechanism by which RBFOX2 (show RBM9 ELISA Kits) regulates protein 4.1R exon 16 splicing through the downstream intronic element UGCAUG.

  10. apo (show C9orf3 ELISA Kits)-calmodulin (show CALM1 ELISA Kits) stabilizes the 4.1R N-terminal domain through interaction with its beta-strand-rich C-lobe and provide a novel function for calmodulin (show CALM1 ELISA Kits), i.e. structural stabilization of 4.1R

Xenopus laevis Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41) interaction partners

  1. Data hypothesize that protein 4.1 (4.1R) could function as a linker protein (show LAT ELISA Kits) between cytokeratin and the actin-based cytoskeleton.

Cow (Bovine) Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41) interaction partners

  1. 4.1G interacts with a subset of CNG (show CNGA1 ELISA Kits) channels and implicate this protein-protein interaction in organizing the spatial arrangement of CNG (show CNGA1 ELISA Kits) channels in the plasma membrane of retinal outer segments.

  2. Band 4.1 protein is found in a retinal cDNA library screened for proteins interacting with the intracellular C-terminus of the metabotropic glutamate (show GRIN2A ELISA Kits) receptor isoform 8a (mGluR8a).

Mouse (Murine) Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41) interaction partners

  1. suggest that 4.1R can prevent pathogenic autoimmunity in MS/EAE progression by suppressing the CD4 (show CD4 ELISA Kits)(+) T cell activation

  2. Loss of 4.1/NuMA (show NUMA1 ELISA Kits) interaction results in spindle orientation defects and inhibition of Cdk1 (show CDK1 ELISA Kits) causes increase in cortical NuMA (show NUMA1 ELISA Kits) localization

  3. a functional role for 4.1R in small intestinal calcium absorption through regulation of membrane expression of PMCA1b (show ATP2B1 ELISA Kits).

  4. At the intercalated disc 4.1R does not colocalise with the adherens junction protein, beta-catenin (show CTNNB1 ELISA Kits), but does overlap with the other plasma membrane signalling proteins, the Na/K-ATPase (show ATP1A1 ELISA Kits) and the Na/Ca exchanger NCX1 (show SLC8A1 ELISA Kits).

  5. Cell adhesion and signaling pathways regulated by alphavbeta8 integrin and Band 4.1B (show EPB41L3 ELISA Kits) are essential for normal formation and function of the heart during embryogenesis.

  6. A conserved exonic splicing silencer element (CE(16)) in protein 4.1R exon 16 (E16 (show SLC7A5 ELISA Kits)) interacts with hnRNP A/B (show HNRNPAB ELISA Kits) proteins & plays a role in repression of E16 (show SLC7A5 ELISA Kits) splicing during early erythropoiesis

  7. We speculate that over the repetitive cycles of heart muscle contraction and relaxation, 4.1R is likely to locate, support, and coordinate functioning of key membrane-bound macromolecular assemblies.[Epb41]

  8. These results suggest that erythroid protein 4.1 plays a major role in volume regulation and physiologically downregulates Na/H exchange in mouse erythrocytes.

  9. 4.1R organizes a macromolecular complex of skeletal and transmembrane proteins at the junctional node.

  10. Cytoskeletal protein (show ADD3 ELISA Kits) 4.1R affects repolarization and regulates calcium handling in the heart.

Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41) Antigen Profile

Antigen Summary

The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with EPB41

  • erythrocyte membrane protein band 4.1b (elliptocytosis 1, RH-linked) (epb41b) antibody
  • erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) (EPB41) antibody
  • erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) (epb41) antibody
  • erythrocyte protein band 4.1 (Epb4.1) antibody
  • 4.1R antibody
  • AI415518 antibody
  • D4Ertd442e antibody
  • EL1 antibody
  • Elp-1 antibody
  • Elp1 antibody
  • Epb41 antibody
  • HE antibody
  • mKIAA4056 antibody
  • P4.1R antibody
  • wu:fb70c02 antibody

Protein level used designations for EPB41

erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) , cha , mot , merlot , chablis , protein 4.1R , cytoskeletal protein 4.1 , protein 4.1 , protein 4.1-like , EPB4.1 , P4.1 , band 4.1 , erythrocyte surface protein band 4.1 , 4.1R , erythroid membrane skeletal protein 4.1 , erythroid protein 4.1

GENE ID SPECIES
326287 Danio rerio
456689 Pan troglodytes
720360 Macaca mulatta
100038195 Xenopus (Silurana) tropicalis
100226658 Taeniopygia guttata
100350667 Oryctolagus cuniculus
100402250 Callithrix jacchus
100455211 Pongo abelii
100546883 Meleagris gallopavo
100563114 Anolis carolinensis
100596891 Nomascus leucogenys
2035 Homo sapiens
442955 Canis lupus familiaris
397741 Xenopus laevis
281753 Bos taurus
396493 Gallus gallus
100515614 Sus scrofa
269587 Mus musculus
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