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anti-Espin (ESPN) Antibodies

ESPN encodes a multifunctional actin-bundling protein. Additionally we are shipping Espin Kits (3) and Espin Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ESPN 83715 B1AK53
ESPN 56226 Q9ET47
ESPN 56227 Q63618
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Top anti-Espin Antibodies at

Showing 10 out of 24 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ESPN Antibody (N-term) in 293 cell line lysat... 0.4 mL Log in to see 6 to 8 Days
Chicken Mouse Un-conjugated IF, WB Western blot analysis of Espin on rat testis lysate. Lane 1, 1:5000, l... 50 μg Log in to see 5 to 6 Days
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of ESPN Antibody (N-term) (ABIN652258) in 293 ce... Formalin-fixed and paraffin-embedded human testis tissue reacted with ... 400 μL Log in to see 10 to 11 Days
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
Human Rabbit Un-conjugated IHC, ELISA, WB 400 μL Log in to see 6 Days
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
Human Rabbit HRP ELISA, WB   200 μL Log in to see 16 Days
Human Rabbit FITC ELISA, WB   200 μL Log in to see 16 Days
Human Rabbit PE ELISA, WB   200 μL Log in to see 16 Days

ESPN Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
, , , , ,
Mouse (Murine) ,
Rat (Rattus) ,

Top referenced anti-Espin Antibodies

  1. Chicken Monoclonal ESPN Primary Antibody for IF, WB - ABIN968627 : Bartles, Zheng, Li, Wierda, Chen: Small espin: a third actin-bundling protein and potential forked protein ortholog in brush border microvilli. in The Journal of cell biology 1998 (PubMed)
    Show all 3 references for ABIN968627

  2. Human Polyclonal ESPN Primary Antibody for EIA, WB - ABIN453641 : Boulouiz, Li, Soualhine, Abidi, Chafik, Nürnberg, Becker, Nürnberg, Kubisch, Wollnik, Barakat: A novel mutation in the Espin gene causes autosomal recessive nonsyndromic hearing loss but no apparent vestibular dysfunction in a Moroccan family. in American journal of medical genetics. Part A 2008 (PubMed)

More Antibodies against Espin Interaction Partners

Human Espin (ESPN) interaction partners

  1. The espin actin-filament-binding site has a major effect on the formation and dynamics of actin bundles.

  2. human deafness and vestibular dysfunction co-segregated with either of two frameshift mutations in ESPN.

  3. The results further strengthen the causative role of the espin gene in non-syndromic hearing loss and add new insights into espin structure and function.

  4. Here, we report a new activity of the espins, one that depends on their enigmatic WH2 domain: the ability to assemble a large actin bundle when targeted to a specific subcellular location.

  5. A recessive ESPN mutation causing congenital hearing loss in a Morocan family was reported.

  6. Flies with mutations affecting the diaphanous,forked, and CG12026/TMHS (show LHFPL5 Antibodies) genes displayed significant reductions in the amplitude of sound-evoked potentials compared to wild-type flies

Mouse (Murine) Espin (ESPN) interaction partners

  1. We demonstrated for the first time that espin regulates both anchorage-dependent growth and anchorage-independent growth in melanoma cells through G1 arrest and modulates the expression and/or activity of p21Cip1 (show CDKN1A Antibodies), p27Kip1 (show CDKN1B Antibodies), Erk (show EPHB2 Antibodies), and Akt (show AKT1 Antibodies).

  2. When myosin IIIB (MYO3B (show MYO3B Antibodies)) is coexpressed with espin-1 (ESPN1), MYO3B (show MYO3B Antibodies) targets and carries ESPN1 to COS7 cell filopodia tips. This tip localization is lost when the ESPN1 C terminus actin-binding site is removed.

  3. espin actin-bundling proteins are required for the assembly and stabilization of the stereociliary parallel actin bundle.

  4. Genetic and physical maps of jerker (Espn(je)) on mouse chromosome 4

  5. Data show that espin actin-bundling proteins, which are the target of the jerker deafness mutation, caused a dramatic, concentration-dependent lengthening of LLC-PK1-CL4 cell microvilli and their parallel actin bundles.

Espin (ESPN) Antigen Profile

Protein Summary

This gene encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement.

Gene names and symbols associated with anti-Espin (ESPN) Antibodies

  • espin (ESPN) antibody
  • espin (TVAG_100530) antibody
  • espin (LOAG_01035) antibody
  • espin (espn) antibody
  • espin (Espn) antibody
  • DFNB36 antibody
  • Je antibody

Protein level used designations for anti-Espin (ESPN) Antibodies

espin , autosomal recessive deafness type 36 protein , ectoplasmic specialization protein , actin cytoskeletal regulatory protein , jerker , Jerker, deafness locus

395461 Gallus gallus
457896 Pan troglodytes
489631 Canis lupus familiaris
4763600 Trichomonas vaginalis G3
9938407 Loa loa
100379704 Xenopus (Silurana) tropicalis
100515838 Sus scrofa
83715 Homo sapiens
56226 Mus musculus
56227 Rattus norvegicus
Selected quality suppliers for anti-Espin (ESPN) Antibodies
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