Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) ELISA Kits

The protein encoded by EHMT1 is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. Additionally we are shipping EHMT1 Antibodies (131) and EHMT1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
EHMT1 77683 Q5DW34
EHMT1 79813 Q9H9B1
Anti-Rat EHMT1 EHMT1 362078  
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Top EHMT1 ELISA Kits at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 15 to 18 Days
$875.60
Details
Mouse
96 Tests Log in to see 15 to 18 Days
$875.60
Details

More ELISA Kits for EHMT1 Interaction Partners

Mouse (Murine) Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) interaction partners

  1. miR (show MLXIP ELISA Kits)-217-mediated, genetic, or pharmacological inactivation of EHMT1/2 was sufficient to promote pathological hypertrophy

  2. EHMT1 Mediates Homeostatic Synaptic Scaling

  3. The stress-induced Brg1 (show SMARCA4 ELISA Kits)-G9a (show EHMT2 ELISA Kits)/GLP (show GOLGA6A ELISA Kits)-Dnmt3 interactions and sequence of repressive chromatin assembly on Myh6 (show MYH6 ELISA Kits) promoter illustrates a molecular mechanism by which the heart epigenetically responds to environmental signals.

  4. data provide genetic and pharmacologic evidence that EHMT1 and EHMT2 (show EHMT2 ELISA Kits) are epigenetic regulators involved in gamma-globin repression and represent a novel therapeutic target for SCD (show SCD ELISA Kits).

  5. histone methyltransferase activities of GLP (show GOLGA6A ELISA Kits) and G9a (show EHMT2 ELISA Kits) are stimulated by neighboring nucleosomes that are premethylated at H3K9

  6. Prdm16 (show PRDM16 ELISA Kits) was required in young mice to suppress the expression of white-fat-selective genes in BAT (show BAAT ELISA Kits) through recruitment of the histone methyltransferase Ehmt1.

  7. G9a (show EHMT2 ELISA Kits) and GLP (show GOLGA6A ELISA Kits) have an essential role in normal morphogenesis of the atrioventricular septum through regulation of the size of the atrioventricular cushion.

  8. Reduced Euchromatin histone methyltransferase 1 (show DNMT1 ELISA Kits) causes developmental delay, hypotonia, and cranial abnormalities associated with increased bone gene expression in Kleefstra syndrome mice.

  9. EHMT1 is an essential BAT (show BAAT ELISA Kits)-enriched lysine methyltransferase in the PRDM16 (show PRDM16 ELISA Kits) transcriptional complex and controls brown adipose cell fate

  10. These data demonstrate that Ehmt1 haploinsufficiency in mice leads to learning deficits and synaptic dysfunction, providing a possible mechanism for the ID phenotype in patients with Kleefstra syndrome

Human Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) interaction partners

  1. missense variants in EHMT1 that lead to protein misfolding and disrupted histone mark binding can lead to Kleefstra Syndrome [case reports]

  2. we find an estrogen receptor (show ESR1 ELISA Kits)-independent synthetic lethal interaction between a GATA3 (show GATA3 ELISA Kits) frameshift mutant with an extended C-terminus and the histone methyltransferases G9A (show EHMT2 ELISA Kits) and GLP (show RCBTB1 ELISA Kits), indicating perturbed epigenetic regulation

  3. Selective degradation of the mutant EHMT1 mRNA leads to Kleefstra syndrome.

  4. G9a (show EHMT2 ELISA Kits) and GLP (show RCBTB1 ELISA Kits) are required for stable maintenance of imprinted DNA methylation (show HELLS ELISA Kits) in embryonic stem cells.

  5. the clinical picture we found in Norwegian patients with Kleefstra syndrome is similar to the findings described in the literature. An interesting point is that in the literature >85% of the patients have a deletion of 9q34.3 and the remaining have a mutation in the EHMT1 gene, whereas in this study we found 50% with a deletion, and 50% with a mutation.

  6. Data indicate zinc finger proteins ZNF644 and WIZ as two core subunits in the histone-lysine N-methyltransferase G9a (show EHMT2 ELISA Kits)/GLP (show RCBTB1 ELISA Kits) complex, and interact with the transcription activation domain of G9a (show EHMT2 ELISA Kits) and GLP (show RCBTB1 ELISA Kits).

  7. data provide genetic and pharmacologic evidence that EHMT1 and EHMT2 (show EHMT2 ELISA Kits) are epigenetic regulators involved in gamma-globin (show HBG1 ELISA Kits) repression and represent a novel therapeutic target for SCD (show SCD ELISA Kits).

  8. The expression level of EHMT1 and EHMT2 (show EHMT2 ELISA Kits) inversely correlates with the type I interferon (show IFNA ELISA Kits) responsiveness in chronic myeloid leukemia (show BCL11A ELISA Kits) cell lines.

  9. The current knowledge on the mechanisms of action and function of EHMT1, with particular emphasis on their interplay in the regulation of chromatin states and biological processes.

  10. Haploinsufficiency of EHMT1 caused by either microdeletions at 9q34.3 or intragenic mutations are associated with Kleefstra syndrome.

EHMT1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome). Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with EHMT1

  • euchromatic histone-lysine N-methyltransferase 1 (EHMT1) antibody
  • euchromatic histone-lysine N-methyltransferase 1 (Ehmt1) antibody
  • euchromatic histone-lysine N-methyltransferase 1 (ehmt1) antibody
  • euchromatic histone-lysine N-methyltransferase 1 (LOC100217666) antibody
  • euchromatic histone methyltransferase 1 (Ehmt1) antibody
  • 9230102N17Rik antibody
  • bA188C12.1 antibody
  • D330003E03 antibody
  • EHMT1 antibody
  • Eu-HMTase1 antibody
  • EUHMTASE1 antibody
  • FP13812 antibody
  • G9a antibody
  • GLP antibody
  • GLP1 antibody
  • KMT1D antibody
  • mKIAA1876 antibody

Protein level used designations for EHMT1

euchromatic histone methyltransferase 1 , histone-lysine N-methyltransferase, H3 lysine-9 specific 5 , euchromatic histone-lysine N-methyltransferase 1 , histone-lysine N-methyltransferase EHMT1 , histone-lysine N-methyltransferase, H3 lysine-9 specific 5-like , G9a-like protein 1 , lysine N-methyltransferase 1D , G9a like protein , H3-K9-HMTase 5 , histone H3-K9 methyltransferase 5

GENE ID SPECIES
417250 Gallus gallus
464891 Pan troglodytes
491224 Canis lupus familiaris
528606 Bos taurus
100023838 Monodelphis domestica
100058869 Equus caballus
100078328 Ornithorhynchus anatinus
100121084 Nasonia vitripennis
100124713 Xenopus (Silurana) tropicalis
100217666 Taeniopygia guttata
100466861 Ailuropoda melanoleuca
100538392 Meleagris gallopavo
100565730 Anolis carolinensis
77683 Mus musculus
79813 Homo sapiens
362078 Rattus norvegicus
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