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Eukaryotic Translation Initiation Factor 3 Subunit A Proteins (EIF3A)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. Additionally we are shipping EIF3A Antibodies (52) and EIF3A Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EIF3A 8661 Q14152
EIF3A 13669 P23116
Rat EIF3A EIF3A 292148 Q1JU68
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Top EIF3A Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

EIF3A Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) Interaction Partners

Human Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) interaction partners

  1. Collybistin (show Arhgef9 Proteins) forms a complex with mTOR (show FRAP1 Proteins) and eIF3 and by sequestering these proteins downregulates mTORC1 signaling and protein synthesis potentially contributing to intellectual disability and autism.

  2. eIF3 has a role in controlling cell size independently of S6K1 (show RPS6KB1 Proteins)-activity

  3. eIF3a (show EIF6 Proteins) improves ovarian cancer patients' response to cisplatin-based chemotherapy by down regulating XPC (show XPC Proteins) and p27(Kip1 (show CDKN1B Proteins)).

  4. eIF3a (show EIF6 Proteins) SNPs are significantly correlated with platinum-based chemotherapy toxicities in Chinese non-small cell lung carcinoma patients.

  5. Data conclude that eIF3a (show EIF6 Proteins) expression may have a profound effect on the urinary bladder cancer phenotype and, in addition, may serve as a prognostic marker for low grade UBCs.

  6. Taken together, these results show that Neurospora crassa eIF3 provides a tractable system for probing the structure and function of human-like eIF3 in the context of living cells.

  7. Of the total, the deregulation of several genes (CDK1 (show CDK1 Proteins), CDK2 (show CDK2 Proteins), CDK4 (show CDK4 Proteins), MCM2 (show MCM2 Proteins), MCM3 (show MCM3 Proteins), MCM4 (show MCM4 Proteins), EIF3a (show EIF6 Proteins) and RPN2 (show PSMD1 Proteins)) were potentially associated with disease development and progression.

  8. At 37 degrees C, P185(HER2 (show ERBB2 Proteins)) internalized through coated pits and vesicles and concentrated in the endosomes and multivesicular bodies in the cells of both cell lines, as well as in lysosomes in cells BT-474

  9. findings suggested altered eIF3a (show EIF6 Proteins) expression closely correlated with p27 (show PAK2 Proteins) status, and the association was of prognostic value for resected NSCLC

  10. eIF3a (show EIF6 Proteins) and eIF3c (show EIF3C Proteins) control abundance and assembly of the entire eIF3 and thus represent its crucial scaffolding elements critically required for formation of preinitiation complexes.

Mouse (Murine) Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) interaction partners

  1. The pleiotropic mouse phenotype extra-toes spotting (show EIF3C Proteins) is caused by translation initiation factor (show TIF1 Proteins) Eif3c (show EIF3C Proteins) mutations.

  2. May play some roles in development and differentiation; decreased eIF3a expression may be a pre-requisite of intestinal epithelial cell differentiation.

  3. Stable expression of a truncated eIF3e (show EIF3E Proteins) in NIH 3T3 cells causes malignant transformation

  4. eIF3a expression oscillated with cell cycle and peaked in S phase. Reducing eIF3a expression also reduced cell proliferation rate by elongating cell cycle but did not change the cell cycle distribution.

EIF3A Protein Profile

Protein Summary

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Gene names and symbols associated with EIF3A

  • eukaryotic translation initiation factor 3, subunit A (EIF3A)
  • eukaryotic translation initiation factor 3 subunit A (eif3a)
  • eukaryotic translation initiation factor 3, subunit 10 (theta) (eif3s10)
  • eukaryotic translation initiation factor 3, subunit A (Eif3a)
  • A830012B05Rik protein
  • Csma protein
  • Eif3 protein
  • eIF3-p170 protein
  • eIF3-theta protein
  • Eif3s10 protein
  • EIF6 protein
  • mKIAA0139 protein
  • P167 protein
  • p180 protein
  • p185 protein
  • TIF32 protein
  • wu:fi15c03 protein
  • zgc:66194 protein
  • zgc:77263 protein
  • ZH12 protein

Protein level used designations for EIF3A

eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa , eukaryotic translation initiation factor 6 , Eukaryotic translation initiation factor 3 subunit 10 , eIF-3-theta , eIF3a , eukaryotic translation initiation factor 3 subunit 10 , eukaryotic translation initiation factor 3 subunit A , EIF3, p180 subunit , centrosomin homolog , cytoplasmic protein p167 , eIF3 p167 , eIF3 p180 , eIF3 p185 , eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD) , eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD) , eukaryotic translation initiation factor 3, subunit 10, 170kD , EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN) , centrosomin , eukaryotic translation initiation factor 3, subunit 10 (theta) , p162

GENE ID SPECIES
100066047 Equus caballus
466216 Pan troglodytes
443632 Xenopus laevis
327515 Danio rerio
8661 Homo sapiens
13669 Mus musculus
423927 Gallus gallus
486914 Canis lupus familiaris
506564 Bos taurus
292148 Rattus norvegicus
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