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anti-Exosome Component 2 (EXOSC2) Antibodies

Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. Additionally we are shipping Exosome Component 2 Proteins (7) and Exosome Component 2 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EXOSC2 23404 Q13868
EXOSC2 227715 Q8VBV3
EXOSC2 366017  
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Top anti-Exosome Component 2 Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-EXOSC2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-EXOSC2 Antibody Titration: 1.25ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate WB Suggested Anti-EXOSC2  Antibody Titration: 1.25 µg/mL ELISA Titer: 1:1562500  Positive Control: Jurkat cell lysate  EXOSC2 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB EXOSC2 Antibody(N-term) (ABIN1881328) western blot analysis in Jurkat cell line lysates (35 µg/lane). This demonstrates the EXOSC2 antibody detected the EXOSC2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA   0.1 mg Log in to see 6 to 8 Days
$742.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged EXOSC2 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated DB 50 μg Log in to see 7 to 9 Days
$285.71
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

EXOSC2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , ,
,
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Mouse (Murine) ,


Rat (Rattus) ,


Top referenced anti-Exosome Component 2 Antibodies

  1. Human Polyclonal EXOSC2 Primary Antibody for WB - ABIN1881328 : Mitchell, Petfalski, Shevchenko, Mann, Tollervey: The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases. in Cell 1997 (PubMed)
    Show all 3 references for ABIN1881328

  2. Human Monoclonal EXOSC2 Primary Antibody for EIA - ABIN1108908 : Raijmakers, Schilders, Pruijn: The exosome, a molecular machine for controlled RNA degradation in both nucleus and cytoplasm. in European journal of cell biology 2004 (PubMed)
    Show all 2 references for ABIN1108908

  3. Cow (Bovine) Polyclonal EXOSC2 Primary Antibody for WB - ABIN2779057 : Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: Large-scale characterization of HeLa cell nuclear phosphoproteins. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)

  4. Chicken Polyclonal EXOSC2 Primary Antibody for WB - ABIN2779056 : van Dijk, Schilders, Pruijn: Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways. in RNA (New York, N.Y.) 2007 (PubMed)

More Antibodies against Exosome Component 2 Interaction Partners

Human Exosome Component 2 (EXOSC2) interaction partners

  1. Knock-down of hRrp41p (show EXOSC4 Antibodies) or hRrp4p but not PM/Scl-100 (show EXOSC10 Antibodies) or PM/Scl-75 (show EXOSC9 Antibodies) leads to codepletion of other subunits.

  2. Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase (show PNPT1 Antibodies)-like ring.

Exosome Component 2 (EXOSC2) Antigen Profile

Protein Summary

Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC2 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC4 and EXOSC7.

Gene names and symbols associated with EXOSC2

  • exosome component 2 (EXOSC2) antibody
  • exosome component 2 (exosc2) antibody
  • exosome component 2 (Bm1_33895) antibody
  • exosome component 2 (PTRG_00114) antibody
  • exosome component 2 (Exosc2) antibody
  • exosc2 antibody
  • fa97b01 antibody
  • hRrp4p antibody
  • MGC97533 antibody
  • p7 antibody
  • Rrp4 antibody
  • Rrp4p antibody
  • wu:fa97b01 antibody
  • zgc:110117 antibody

Protein level used designations for EXOSC2

exosome component 2 , exosome complex component RRP4 , exosome complex exonuclease RRP4 , homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4) , homolog of yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease , ribosomal RNA-processing protein 4 , homolog of Yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease , homolog of Yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exorib

GENE ID SPECIES
464801 Pan troglodytes
595050 Xenopus (Silurana) tropicalis
715960 Macaca mulatta
6101667 Brugia malayi
6340437 Pyrenophora tritici-repentis Pt-1C-BFP
23404 Homo sapiens
608606 Canis lupus familiaris
615712 Bos taurus
227715 Mus musculus
366017 Rattus norvegicus
550234 Danio rerio
444032 Xenopus laevis
417182 Gallus gallus
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