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F-Box Protein 45 Proteins (FBXO45)

Members of the F-box protein family, such as FBXO45, are characterized by an approximately 40-amino acid F-box motif. Additionally we are shipping FBXO45 Antibodies (18) and FBXO45 Kits (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FBXO45 200933 P0C2W1
FBXO45 268882 Q8K3B1
FBXO45    
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Top FBXO45 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,579.50
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,735.33
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,740.83
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,768.33
Details

FBXO45 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for F-Box Protein 45 (FBXO45) Interaction Partners

Human F-Box Protein 45 (FBXO45) interaction partners

  1. Data show that epithelial-mesenchymal transition (EMT (show ITK Proteins))-transcription factors can be dynamically degraded by an atypical ubiquitin E3 ligase complex Skp1 (show SKP1 Proteins)-Pam (show PAM Proteins)-Fbxo45 (SPFFbxo45).

  2. Fbxo45 is the substrate-receptor subunit of a functional E3 ligase for Par-4 (show PAWR Proteins) that has a critical role in cancer cell survival.

  3. Study found that the R108C mutation in FBXO45 is a rare variant with a modest effect on schizophrenia risk that may disrupt the structure and function of the FBXO45 protein

  4. FBXO45 gene consisting of 3 exons, and the vicinity of the transcriptional start site had several estrogen receptor (show ESR1 Proteins) binding consensus sequences.

  5. FBXO45 promotes the proteasome-dependent degradation of p73 (show TP73 Proteins).

Mouse (Murine) F-Box Protein 45 (FBXO45) interaction partners

  1. Fbxo45 binds to N-cadherin (show CDH2 Proteins) intracellularly and prevents its degradation thereby playing a key role in promoting N-cadherin (show CDH2 Proteins)-mediated neuronal differentiation.

  2. Data suggest that Fbxo45 plays an important role in the regulation of neurotransmission by modulating Munc13-1 at the synapse.

  3. Results suggest that Fbxo45 forms a novel Fbxo45-PAM ubiquitin ligase complex that plays an important role in neural development.

FBXO45 Protein Profile

Protein Summary

Members of the F-box protein family, such as FBXO45, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (summary by Jin et al., 2004

Gene names and symbols associated with F-Box Protein 45 Proteins (FBXO45)

  • F-box protein 45 (FBXO45)
  • F-box protein 45 (fbxo45)
  • F-box protein 45 (LOC100340768)
  • F-box protein 45 (Fbxo45)
  • 3g27 protein
  • 2610017J04Rik protein
  • AI463119 protein
  • BC026799 protein
  • Fbx45 protein
  • zgc:65875 protein

Protein level used designations for F-Box Protein 45 Proteins (FBXO45)

F-box protein 45 , F-box/SPRY domain-containing protein 1 , F-box only protein 45 , hFbxo45 , mFbxo45 , cyclin-like F-box and SPla/RYanodine receptor SPRY (36.8 kD) (3G27)

GENE ID SPECIES
471091 Pan troglodytes
533064 Bos taurus
100216147 Xenopus (Silurana) tropicalis
100340768 Oryctolagus cuniculus
200933 Homo sapiens
268882 Mus musculus
393567 Danio rerio
380431 Xenopus laevis
770111 Gallus gallus
488031 Canis lupus familiaris
100714245 Cavia porcellus
101123179 Ovis aries
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