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F-Box and Leucine-Rich Repeat Protein 2 Proteins (FBXL2)

FBXL2 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. Additionally we are shipping FBXL2 Antibodies (42) and FBXL2 Kits (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FBXL2 25827 Q9UKC9
FBXL2 72179 Q8BH16
Rat FBXL2 FBXL2 363156  
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Top FBXL2 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,179.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

FBXL2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for F-Box and Leucine-Rich Repeat Protein 2 (FBXL2) Interaction Partners

Human F-Box and Leucine-Rich Repeat Protein 2 (FBXL2) interaction partners

  1. these results uncover a previous unknown network involving FBXL2 and FoxM1 (show FOXM1 Proteins) in the regulation of gastric cancer growth.

  2. FBXL2 recognizes Trp-73 within NALP3 for interaction and targets Lys-689 within NALP3 for ubiquitin ligation and degradation.

  3. FBXL2 mediates the ubiquitylation and degradation of p85beta on cell membranes.

  4. These results suggested that the involvement of the reduction of FBL2 level is related to AD progression.

  5. FBXL2 is indispensible regulator of mitosis that serves as a tumor suppressor

  6. FBXL2 targets cyclin D2 (show CCND2 Proteins) for ubiquitination and degradation to inhibit leukemic cell proliferation.

  7. FBL2 is a novel and dual regulator of amyloid precursor protein (APP (show APP Proteins)) metabolism through FBL2-dependent ubiquitination of APP (show APP Proteins).

Mouse (Murine) F-Box and Leucine-Rich Repeat Protein 2 (FBXL2) interaction partners

  1. FBXL2 mediates Aurora B (show AURKC Proteins) ubiquitination and degradation within the midbody, which is sufficient to induce mitotic arrest and apoptosis.

  2. FBXL2 is a ubiquitin E3 ligase subunit that triggers mitotic arrest.

FBXL2 Protein Profile

Protein Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with FBXL2

  • F-box and leucine-rich repeat protein 2 (FBXL2)
  • F-box and leucine-rich repeat protein 2 (fbxl2)
  • F-box and leucine-rich repeat protein 2 (Fbxl2)
  • F-box and leucine-rich repeat protein 20 (Fbxl20)
  • 2810423A21Rik protein
  • Fbl2 protein
  • Fbl3 protein
  • Fbxl2 protein
  • fbxl20 protein
  • RGD1562243 protein
  • sb:cb783 protein
  • zgc:73374 protein

Protein level used designations for FBXL2

F-box protein FBL2/FBL3 , F-box protein containing leucine-rich repeats , F-box/LRR-repeat protein 2 , F-box and leucine-rich repeat protein 20 , F-box protein FBL2 , F-box/LRR-repeat protein 20

GENE ID SPECIES
25827 Homo sapiens
616212 Bos taurus
378737 Danio rerio
485573 Canis lupus familiaris
72179 Mus musculus
363156 Rattus norvegicus
64039 Rattus norvegicus
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