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Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. Additionally we are shipping FBXL20 Antibodies (31) and FBXL20 Kits (12) and many more products for this protein.
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which provides a signal to promote its ubiquitination and proteasomal degradation mediated by FBXL20 and the associated Skp1 (show SKP1 Proteins)-Cullin1 complex, leading to inhibition of autophagy and receptor endocytosis
study concludes FBXL20 plays an essential role in the carcinogenesis of colorectal adenocarcinoma and promotes carcinogenesis through the regulation of the Wnt (show WNT2 Proteins) signaling pathway and caspase (show CASP3 Proteins) activation
SCRAPPER plays a critical role in the anterior cingulate cortex pre-long term potentiation as well as synaptic transmission.
SCRAPPER regulates the threshold of bidirectional synaptic plasticity and, therefore, metaplasticity.
The behavioral phenotypes of Scrapper mutant mice suggest that molecular degradation conferred by SCRAPPER play important roles in hippocampal-dependent fear memory formation.
SCRAPPER is synapse localized E3 ubiquitin ligase which binds/ubiquinates RIM1 to regulate synaptic transmission.
Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004
F-box protein FBL2
, F-box/LRR-repeat protein 20
, F-box and leucine-rich repeat protein 20
, F-box/LRR-repeat protein 20-like
, F-box/LRR-repeat protein 2
, F-box and leucine-rich repeat protein 2