F-Box and Leucine-Rich Repeat Protein 12 Proteins (FBXL12)

Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. Additionally we are shipping FBXL12 Antibodies (41) and FBXL12 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FBXL12 54850 Q9NXK8
FBXL12 30843 Q9EPX5
Rat FBXL12 FBXL12 313782  
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Top FBXL12 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,876.50
Details
Yeast Arabidopsis thaliana His tag   1 mg Log in to see 60 to 71 Days
$3,091.00
Details

FBXL12 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for F-Box and Leucine-Rich Repeat Protein 12 (FBXL12) Interaction Partners

Human F-Box and Leucine-Rich Repeat Protein 12 (FBXL12) interaction partners

  1. Study found that Fbl12 binds and ubiquitinates p21 (show CDKN1A Proteins) which allows its stability. In addition, Fbl12 regulates default degradation under basal conditions but not under UV-stimulated conditions. These findings elucidate novel mechanisms that underlie the regulation of p21 (show CDKN1A Proteins) expression level in cells.

  2. FBXL12 plays a key role in the down-regulation of ALDH3 (show ALDH3A1 Proteins) activity in trophoblast stem cells and thus initiates trophoblast differentiation during placental development.

  3. Fbxl12-induced CaMKI (show CAMK1 Proteins) degradation attenuates p27 (show PAK2 Proteins) phosphorylation at these sites in early G1 and iii) activation of CaMKI (show CAMK1 Proteins) during G1 transition followed by p27 (show PAK2 Proteins) phosphorylation appears to be upstream to other p27 (show PAK2 Proteins) phosphorylation events

Mouse (Murine) F-Box and Leucine-Rich Repeat Protein 12 (FBXL12) interaction partners

  1. Study investigated the role of FBXL12 in T-cell development by examination of FBXL12-null mice, finding that the FBXL12-ALDH3 (show ALDH3A1 Proteins) axis plays a key role in regulation of the positive selection of T cells.

FBXL12 Protein Profile

Protein Summary

Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004

Gene names and symbols associated with FBXL12

  • hepatic lectin (LOC396477)
  • F-box and leucine rich repeat protein 12 (FBXL12)
  • F-box and leucine-rich repeat protein 12 (fbxl12)
  • F-box and leucine-rich repeat protein 12 (Fbxl12)
  • RNI-like superfamily protein (AT3G07550)
  • 3110048D16Rik protein
  • Fbl12 protein
  • FBXL12 protein

Protein level used designations for FBXL12

hepatic lectin , F-box and leucine-rich repeat protein 12 , F-box/LRR-repeat protein 12-like , f-box/LRR-repeat protein 12-like , F-box protein FBL12 , F-box/LRR-repeat protein 12 , F-box protein containing leucine repeats 12

GENE ID SPECIES
396477 Gallus gallus
455688 Pan troglodytes
710855 Macaca mulatta
100135148 Xenopus (Silurana) tropicalis
100347448 Oryctolagus cuniculus
100395307 Callithrix jacchus
100459856 Pongo abelii
100590688 Nomascus leucogenys
484965 Canis lupus familiaris
54850 Homo sapiens
30843 Mus musculus
313782 Rattus norvegicus
617304 Bos taurus
101110231 Ovis aries
819944 Arabidopsis thaliana
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