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FK506 Binding Protein 10, 65 KDa Proteins (FKBP10)

The protein encoded by FKBP10 belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. Additionally we are shipping FK506 Binding Protein 10, 65 KDa Antibodies (61) and FK506 Binding Protein 10, 65 KDa Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FKBP10 14230 Q61576
Rat FKBP10 FKBP10 360627  
FKBP10 60681 Q96AY3
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Top FK506 Binding Protein 10, 65 KDa Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$950.40
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$985.60
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,125.10
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,156.57
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

FKBP10 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for FK506 Binding Protein 10, 65 KDa (FKBP10) Interaction Partners

Mouse (Murine) FK506 Binding Protein 10, 65 KDa (FKBP10) interaction partners

  1. Data suggest a requirement for FKBP65 function during embryonic connective tissue development in mice; its expression is restricted postnatally in bone, ligaments and tendons.

  2. FKBP65 may act as an elastin (show ELN Proteins) chaperone in vivo by controlling both the coacervation and the maturation stages of its selfassembly into fibrils.

Human FK506 Binding Protein 10, 65 KDa (FKBP10) interaction partners

  1. Mutations in the HSP47 and FKBP65 produce a moderately severe form of Osteogenesis imperfect.

  2. CTSD (show CTSD Proteins), FKBP10, and SLC2A1 (show SLC2A1 Proteins) are novel genes that participate in the acquisition and maintenance of the adriamycin-resistant phenotype in leukemia cells.

  3. Results imply that FKBP10 mutations affect collagen indirectly, by ablating FKBP65 support for collagen telopeptide hydroxylation by lysyl hydroxylase 2 (show PLOD2 Proteins), thus decreasing collagen cross-links in tendon and bone matrix.

  4. Elastin (show ELN Proteins) binding protein and FKBP65 modulate the kinetics of self-assembly of tropoelastin (show ELN Proteins) in an in vitro system.

  5. FKBP10 depletion enhances glucocerebrosidase (show GBA Proteins) proteostasis in Gaucher disease fibroblasts

  6. underexpression of FKBP65 protein is characteristic of high-grade serous carcinomas and this expression profile may be linked to molecular pathways associated with an unfavourable outcome in cancer patients.

  7. FKBP10 acts during procollagen maturation to contribute to molecular stability and post-translational modification of type I procollagen (show COL1A2 Proteins), without which bone mass and quality are abnormal and fractures and contractures result

  8. identified a Palestinian pedigree with moderate and lethal forms of recessive OI caused by mutations in FKBP10 or PPIB (show PPIB Proteins), which encode endoplasmic reticulum resident chaperone/isomerases FKBP65 and CyPB (show PPIB Proteins), respectively

  9. Homozygosity mapping identified FKBP10 as a candidate gene, and sequencing revealed a base pair exchange that causes a C-terminal premature stop codon in this gene.

  10. Mutations in FKBP10 cause both Bruck syndrome and isolated osteogenesis imperfecta (show COL1A2 Proteins) in humans.

FK506 Binding Protein 10, 65 KDa (FKBP10) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.

Gene names and symbols associated with FKBP10

  • FK506 binding protein 10, 65 kDa (fkbp10)
  • FK506 binding protein 10, 65 kDa (FKBP10)
  • FK506 binding protein 10b (fkbp10b)
  • FK506 binding protein 10 (Fkbp10)
  • AI325255 protein
  • FKBP-10 protein
  • FKBP-65 protein
  • Fkbp-rs1 protein
  • Fkbp1-rs protein
  • Fkbp6 protein
  • FKBP10 protein
  • FKBP65 protein
  • Fkbprp protein
  • hFKBP65 protein
  • MGC82987 protein
  • OI6 protein
  • OI11 protein
  • PPIASE protein
  • wu:fc27c03 protein

Protein level used designations for FKBP10

FK506 binding protein 10 , FK506 binding protein 10, 65 kDa , peptidyl-prolyl cis-trans isomerase FKBP10 , FK506-binding protein , peptidyl-prolyl cis-trans isomerase FKBP10-like , 65 kDa FK506-binding protein , 65 kDa FKBP , FK506 binding protein 6 (65 kDa) , FK506-binding protein 10 , PPIase FKBP10 , immunophilin FKBP65 , rotamase , FKBP-10 , FKBP-65

GENE ID SPECIES
447040 Xenopus laevis
707881 Macaca mulatta
741603 Pan troglodytes
324381 Danio rerio
398175 Xenopus laevis
549537 Xenopus (Silurana) tropicalis
100012883 Monodelphis domestica
100438077 Pongo abelii
100562955 Anolis carolinensis
100600793 Nomascus leucogenys
14230 Mus musculus
360627 Rattus norvegicus
60681 Homo sapiens
535310 Bos taurus
490975 Canis lupus familiaris
100511038 Sus scrofa
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