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anti-FSHD Region Gene 1 (FRG1) Antibodies

FRG1 maps to a location 100 kb centromeric of the repeat units on chromosome 4q35 which are deleted in facioscapulohumeral muscular dystrophy (FSHD). Additionally we are shipping FSHD Region Gene 1 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FRG1 361156  
FRG1 2483 Q14331
FRG1 14300 P97376
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Top anti-FSHD Region Gene 1 Antibodies at antibodies-online.com

Showing 10 out of 70 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated EIA, WB AP20113PU-N FRG1 antibody staining of Jurkat nuclear lysate at 2 µg/ml (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of FRG1 Antibody (C-term) in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the FRG1 antibody detected the FRG1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Frg1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Rat Liver WB Suggested Anti-Frg1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Rat Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Frg1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Mouse Brain WB Suggested Anti-Frg1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Mouse Brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB FRG1 Antibody (C-term)  western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the FRG1 antibody detected the FRG1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of purified MaxPab antibody to FRG1 on HeLa cell. [antibody concentration 10 ug/ml] Western Blot analysis of FRG1 expression in transfected 293T cell line by FRG1 MaxPab polyclonal antibody.Lane 1: FRG1 transfected lysate(28.38 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IF, IP, ELISA, WB FRG1 monoclonal antibody (M01), clone 4A5 Western Blot analysis of FRG1 expression in Hela S3 NE . Western Blot analysis of FRG1 expression in transfected 293T cell line by FRG1 monoclonal antibody (M01), clone 4A5.Lane 1: FRG1 transfected lysate(29 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$430.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Rat Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

FRG1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-FSHD Region Gene 1 Antibodies

  1. Human Polyclonal FRG1 Primary Antibody for EIA, WB - ABIN952390 : Gabellini, DAntona, Moggio, Prelle, Zecca, Adami, Angeletti, Ciscato, Pellegrino, Bottinelli, Green, Tupler: Facioscapulohumeral muscular dystrophy in mice overexpressing FRG1. in Nature 2006 (PubMed)
    Show all 2 references for ABIN952390

  2. Human Polyclonal FRG1 Primary Antibody for IF, WB - ABIN515816 : Ferri, Huichalaf, Caccia, Gabellini: Direct interplay between two candidate genes in FSHD muscular dystrophy. in Human molecular genetics 2015 (PubMed)

  3. Human Monoclonal FRG1 Primary Antibody for IF, IP - ABIN560950 : Wallace, Garwick-Coppens, Tupler, Harper: RNA interference improves myopathic phenotypes in mice over-expressing FSHD region gene 1 (FRG1). in Molecular therapy : the journal of the American Society of Gene Therapy 2011 (PubMed)

  4. Human Polyclonal FRG1 Primary Antibody for EIA, WB - ABIN498026 : Hanel, Wuebbles, Jones: Muscular dystrophy candidate gene FRG1 is critical for muscle development. in Developmental dynamics : an official publication of the American Association of Anatomists 2009 (PubMed)

More Antibodies against FSHD Region Gene 1 Interaction Partners

Human FSHD Region Gene 1 (FRG1) interaction partners

  1. Our results demonstrate that FRG1 is a direct DUX4 transcriptional target uncovering a novel regulatory circuit contributing to Facioscapulohumeral muscular dystrophy.

  2. FRG1 mice overexpressing FHL1 (show FHL1 Antibodies) showed an improvement in the dystrophic phenotype

  3. This study suggests a novel role of FRG1 as epigenetic regulator of muscle differentiation and indicates that Suv4-20h1 (show SUV420H1 Antibodies) has a gene-specific function in myogenesis.

  4. depressed myoblast proliferation may contribute to the pathology of mice overexpressing FRG1 and may play a part in facioscapulohumeral muscular dystrophy

  5. These data provide the first biochemical activities (actin binding and RNA binding) for human FRG1 and the characterization of the endogenous human FRG1, together indicating that FRG1 is involved in multiple aspects of RNA biogenesis.

  6. in muscle FRG1 is a developmentally regulated sarcomeric protein suggesting FRG1 may perform a muscle-specific (show EIF3K Antibodies) function

  7. FRG1 transgenic mice develop a muscular dystrophy with features characteristic of the human disease; by contrast, FRG2 and ANT1 (show SLC25A4 Antibodies) transgenic mice seem normal

  8. differently from normal myoblasts, the 4qA/B marker interacted directly with the promoters of the FRG1 and ANT1 (show SLC25A4 Antibodies) genes in Facio-Scapulo-Humeral Dystrophy cells

  9. Data show that frg1 is expressed in and essential for the development of the tadpole musculature, and suggest that maintenance of normal FRG1 levels is critical for proper muscle development in frogs and humans.

  10. study compared chromatin structure & tridimensional interaction of the D4Z4 array and FRG1 gene promoter, and FRG1 expression, in control and FSHD cells

Mouse (Murine) FSHD Region Gene 1 (FRG1) interaction partners

  1. Mouse Frg1 genomic area lacks DUX4 binding sites and DUX4 is unable to activate the endogenous mouse Frg1 gene providing a possible explanation for the lack of muscle phenotype in DUX4 transgenic mice.

  2. This study suggests a novel role of FRG1 as epigenetic regulator of muscle differentiation and indicates that Suv4-20h1 (show SUV420H1 Antibodies) has a gene-specific function in myogenesis.

  3. On the basis of these results, it was proposed that aberrant fTnT represents a biological marker of muscle phenotype severity and disease progression.

  4. our results suggest that a component of FSHD pathogenesis may arise by over-expression of FRG1, reducing Rbfox1 (show A2BP1 Antibodies) levels and leading to aberrant expression of an altered Calpain 3 (show CAPN3 Antibodies) protein through dysregulated splicing

FSHD Region Gene 1 (FRG1) Antigen Profile

Protein Summary

This gene maps to a location 100 kb centromeric of the repeat units on chromosome 4q35 which are deleted in facioscapulohumeral muscular dystrophy (FSHD). It is evolutionarily conserved and has related sequences on multiple human chromosomes but DNA sequence analysis did not reveal any homology to known genes. In vivo studies demonstrate the encoded protein is localized to the nucleolus.

Gene names and symbols associated with FRG1

  • FSHD region gene 1-like (Frg1l) antibody
  • FSHD region gene 1 (FRG1) antibody
  • FSHD region gene 1 (frg1) antibody
  • FSHD region gene 1 (LOC100345738) antibody
  • FRG1 protein (frg1) antibody
  • FSHD region gene 1 (Frg1) antibody
  • frg1 antibody
  • FRG1A antibody
  • FSG1 antibody
  • MGC84293 antibody
  • MGC89908 antibody

Protein level used designations for FRG1

FSHD region gene 1-like , FSHD region gene 1 , protein FRG1 , FSHD region gene 1 protein , facioscapulohumeral muscular dystrophy region gene-1

GENE ID SPECIES
361156 Rattus norvegicus
422726 Gallus gallus
444679 Xenopus laevis
448726 Xenopus (Silurana) tropicalis
482899 Canis lupus familiaris
698743 Macaca mulatta
738279 Pan troglodytes
100345738 Oryctolagus cuniculus
445937 Takifugu rubripes
2483 Homo sapiens
14300 Mus musculus
689484 Rattus norvegicus
512533 Bos taurus
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