anti-Fanconi Anemia, Complementation Group C (FANCC) Antibodies

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). Additionally we are shipping Fanconi Anemia, Complementation Group C Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FANCC 2176 Q00597
FANCC 14088  
FANCC 24361  
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Top anti-Fanconi Anemia, Complementation Group C Antibodies at antibodies-online.com

Showing 10 out of 110 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB FANCC Antibody (C-term) (ABIN653475) western blot analysis in HL-60,HepG2 cell line lysates (35 µg/lane).This demonstrates the FANCC antibody detected the FANCC protein (arrow). FANCC Antibody (C-term)(ABIN653475) IHC analysis in formalin fixed and paraffin embedded testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Chimpanzee Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 12 to 15 Days
$411.18
Details
Human Rabbit Un-conjugated EIA, FACS, IF, IHC (p), WB   0.4 mL Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated WB Western Blot: FANCC Antibody [ABIN251003] - Detection of FANC C in transfected COS1 cell lysate using ABIN251003. 0.1 mL Log in to see 7 to 9 Days
$381.94
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: FANCC Antibody [NBP1-03280] - Staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 0.05 mg Log in to see 10 to 13 Days
$447.56
Details
Human Rabbit Un-conjugated IHC (p), WB Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using affinity purified anti-FANCC antibody shows detection of a band at ~63 kDa (arrowhead) corresponding to FANCC present in a HeLa whole cell lysate.  The identity of the lower molecular weight band is unknown.  Approximately 35 µg of lysate was separated by 4-20% Tris Glycine SDS-PAGE. After blocking, the membrane was probed overnight at 4°C with the primary antibody diluted to 1:1,500 in PBS supplemented with 1% normal goat serum and 0.1% BLOTTO (B501-0500). The membrane was washed and reacted with a 1:10,000 dilution of IRDye™800 conjugated Gt-a-Rabbit IgG [H&L] (611-132-122) for 45 min at room temperature (800 nm channel, green).  Molecular weight estimation was made by comparison to prestained MW markers (indicated at left).  IRDye™800 fluorescence image was captured using the Odyssey® Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc.  Other detection systems will yield similar results. 100 μg Log in to see 1 to 2 Days
$379.00
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Immunofluorescence analysis of paraformaldehyde-fixed HeLa, merged with DNA probe, using FANCC antibody at 1:200 dilution. Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using FANCC antibody at 1:200 dilution. 50 μL Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of various cell lines, using FANCC antibody. 100 μL Log in to see 16 Days
$323.13
Details

FANCC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Fanconi Anemia, Complementation Group C Antibodies

  1. Human Polyclonal FANCC Primary Antibody for FACS, IF - ABIN653475 : McWilliams, Bamlet, de Andrade, Rider, Couch, Cunningham, Matsumoto, Rabe, Hammer, Petersen: Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009 (PubMed)
    Show all 4 references for 653475

  2. Human Polyclonal FANCC Primary Antibody for WB - ABIN251003 : Yung, Tilgner, Ledran, Habibollah, Neganova, Singhapol, Saretzki, Stojkovic, Armstrong, Przyborski, Lako: Brief report: human pluripotent stem cell models of fanconi anemia deficiency reveal an important role for fanconi anemia proteins in cellular reprogramming and survival of hematopoietic progenitors. in Stem cells (Dayton, Ohio) 2013 (PubMed)

  3. Human Polyclonal FANCC Primary Antibody for ELISA, ICC - ABIN4310504 : Moeller, Yordy, Williams, Giri, Raju, Molkentine, Byers, Heymach, Story, Lee, Sturgis, Weber, Garden, Ang, Schwartz: DNA repair biomarker profiling of head and neck cancer: Ku80 expression predicts locoregional failure and death following radiotherapy. in Clinical cancer research : an official journal of the American Association for Cancer Research 2011 (PubMed)

More Antibodies against Fanconi Anemia, Complementation Group C Interaction Partners

Human Fanconi Anemia, Complementation Group C (FANCC) interaction partners

  1. Lung adenocarcinomas in both male and female patients were associated with (a) genotypic polymorphisms of FANCC and FANCD1 (show BRCA2 Antibodies).

  2. Israeli ATM (show ATM Antibodies), BLM, and FANCC heterozygous mutation carriers are not at an increased risk for developing cancer.

  3. FANCC interacts and co-localizes with STMN1 (show STMN1 Antibodies) at centrosomes during mitosis. We also showed that FANCC is required for STMN1 (show STMN1 Antibodies) phosphorylation.

  4. FANCC interferes with UNC5A's functions in apoptosis and suggest that FANCC may participate in developmental processes through association with the dependence receptor UNC5A (show UNC5A Antibodies).

  5. The successful in vitro repair of the mutated Fanconi anemia (show PALB2 Antibodies) FANCC gene using the CRISPR/Cas9 system has been described.

  6. Data indicate that TLR-indu (show IL1B Antibodies)ced IL-1beta overproduction in FANCA- and FANCC-deficie (show CRK Antibodies)nt mononuclear phagocyte cell lines and primary cells requires activation of the inflammasome.

  7. deregulations of the FANCC-mediated DNA damage repair pathway and the PTCH1 (show PTCH1 Antibodies)-associated sonic hedgehog (show SHH Antibodies) pathway are associated with the development of early dysplastic head and neck lesions.

  8. we identified faults in two genes, Fanconi C and Bloom helicase( FANCC and BLM), in six families. Faults in these genes appear to increase the risk of developing breast cancer

  9. FANCC polymorphisms might be associated with the obstructive symptoms in allergic diseases.

  10. FA DNA repair genes, FANCD2 (show FANCD2 Antibodies), FANCL (show FANCL Antibodies), and FANCC, are transcriptionally upregulated differently in melanoma compared with non-melanoma skin cancer

Mouse (Murine) Fanconi Anemia, Complementation Group C (FANCC) interaction partners

  1. Genetic deletion of Fancc blocks the autophagic clearance of viruses (virophagy) and increases susceptibility to lethal viral encephalitis. Fanconi anemia complementation group C (FANCC) protein interacts with Parkin (show PARK2 Antibodies), is required in vitro and in vivo for clearance of damaged mitochondria, and decreases mitochondrial reactive oxygen species (ROS (show ROS1 Antibodies)) production and inflammasome activation.

  2. Data show that Fanconi anemia (show PALB2 Antibodies), complementation group C protein (show HNRNPC Antibodies) knockout (Fancc -/-) mice develop hematopoietic chromosomal instability followed by leukemia in an age-dependent manner.

  3. Loss of Fancc Impairs Antibody-Secreting Cell Differentiation in Mice through Deregulating the Wnt (show WNT2 Antibodies) Signaling Pathway

  4. Combined deficiency of Foxo3a (show FOXO3 Antibodies) and Fancc or Fancd2 (show FANCD2 Antibodies) not only impairs the self-renewal capacity but also markedly increases the apoptosis of neural stem and progenitor cells (NSPCs), leading to defective neurogenesis.

  5. Using mice deficient in both Mus81 (show MUS81 Antibodies) and the FA pathway protein FancC, we show both proteins cooperate in parallel pathways, as concomitant loss of FancC and Mus81 (show MUS81 Antibodies) triggered cell-type-specific proliferation arrest, apoptosis and DNA damage accumulation in utero.

  6. Loss of FANCC leads to a drastic increase in stalled/collapsed forks in cells carrying an Mcm4 (show MCM4 Antibodies) missense mutation.

  7. FANCC is most likely to be critical for resistance to DNA cross-linking drug-induced DNA damage in cells transformed by JAK2 (show JAK2 Antibodies) V617F mutant.

  8. Data indicate that IL-1beta (show IL1B Antibodies) overproduction from FANCC-deficient macrophages is p38 (show CRK Antibodies) dependent.

  9. Loss of FANCC expression results in an impaired emergency granulopoiesis response in a transgenic mouse model of Fanconi anemia (show PALB2 Antibodies).

  10. Compromised hematopoiesis in Fancc(-/-) animals is developmentally programmed and does not arise de novo in bone marrow.

Fanconi Anemia, Complementation Group C (FANCC) Antigen Profile

Protein Summary

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C.

Gene names and symbols associated with FANCC

  • Fanconi anemia, complementation group C (FANCC) antibody
  • Fanconi anemia, complementation group C (fancc) antibody
  • Fanconi anemia, complementation group C (Fancc) antibody
  • BB116513 antibody
  • FA3 antibody
  • FAC antibody
  • Facc antibody
  • FANCC antibody
  • zgc:154105 antibody

Protein level used designations for FANCC

Fanconi anemia, complementation group C protein , Fanconi anemia C , Fanconi anemia, complementation group C , fanconi anemia group C protein-like , Fanconi anemia group C protein-like , Fanconi anemia group C protein , Fanconi anemia group C protein homolog

GENE ID SPECIES
427468 Gallus gallus
692127 Danio rerio
709398 Macaca mulatta
100061359 Equus caballus
100329211 Xenopus laevis
100344788 Oryctolagus cuniculus
100409306 Callithrix jacchus
100461880 Pongo abelii
2176 Homo sapiens
465257 Pan troglodytes
14088 Mus musculus
24361 Rattus norvegicus
281762 Bos taurus
607277 Canis lupus familiaris
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