FANCC antibody (AA 319-558)

Catalog No. ABIN3022594

The Rabbit Polyclonal anti-FANCC antibody (ABIN3022594) specifically detects FANCC in WB, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for FANCC antibody (AA 319-558) (ABIN3022594)

Target: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FANCC Antibody

Binding Specificity: AA 319-558

Sequence: TQCFVEALEK ASKQLRFALK TYFPYTSPSL AMVLLQDPQD IPRGHWLQTL KHISELLREA VEDQTHGSCG GPFESWFLFI HFGGWAEMVA EQLLMSAAEP PTALLWLLAF YYGPRDGRQQ RAQTMVQVKA VLGHLLAMSR SSSLSAQDLQ TVAGQGTDTD LRAPAQQLIR HLLLNFLLWA PGGHTIAWDV ITLMAHTAEI THEIIGFLDQ TLYRWNRLGI ESPRSEKLAR ELLKELRTQV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 319-558 of human FANCC (NP_000127.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FANCC

Target: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Alternative Name: FANCC

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C.,FANCC,FA3,FAC,FACC,Epigenetics & Nuclear Signaling,DNA Damage & Repair,FANCC

Molecular Weight: 63 kDa

Gene ID: 2176

UniProt: Q00597

Pathways: DNA Damage Repair