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The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). Additionally we are shipping Fanconi Anemia Complementation Group G Proteins (3) and Fanconi Anemia Complementation Group G Kits (2) and many more products for this protein.
Showing 10 out of 137 products:
Human Polyclonal FANCG Primary Antibody for WB - ABIN251005
Park, Ciccone, Beck, Hwang, Freie, Clapp, Lee: Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins. in The Journal of biological chemistry 2004
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Human Polyclonal FANCG Primary Antibody for IHC - ABIN966130
Liu, Lamerdin, Tucker, Zhou, Walter, Albala, Busch, Thompson: The human XRCC9 gene corrects chromosomal instability and mutagen sensitivities in CHO UV40 cells. in Proceedings of the National Academy of Sciences of the United States of America 1997
Show all 6 Pubmed References
Human Polyclonal FANCG Primary Antibody for IHC - ABIN966129
Garcia-Higuera, Kuang, Näf, Wasik, DAndrea: Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex. in Molecular and cellular biology 1999
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Human Monoclonal FANCG Primary Antibody for IF, IP - ABIN560843
Hinz, Nham, Yamada, Tebbs, Salazar, Hinz, Mohrenweiser, Jones, Thompson: Four human FANCG polymorphic variants show normal biological function in hamster CHO cells. in Mutation research 2006
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Human Polyclonal FANCG Primary Antibody for ELISA, WB - ABIN449536
Tomida, Itaya, Shigechi, Unno, Uchida, Ikura, Masuda, Matsuda, Adachi, Kobayashi, Meetei, Maehara, Yamamoto, Kamiya, Matsuura, Matsuda, Ikura, Ishiai, Takata: A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair. in Nucleic acids research 2013
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Identification of the Xenopus laevis ortholog of human FANCG (xFANCG), its expression during development, and its molecular interactions with a partner protein, xFANCA
studied the impact of mutations on the function and structure of FANCG
Patients, homozygous for the FANCG founder mutation, present with severe cytopenia but progress to bone marrow failure at similar ages to other individuals affected with Fanconi anemia (show PALB2 Antibodies) of heterogeneous genotype.
founder haplotype analysis of FANCG for the Korean Fanconi anemia (show PALB2 Antibodies) population
A new role of FANCG in Homologous recombination repair of interstrand crosslinks through K63Ub-mediated interaction with the Rap80-BRCA1 complex.
FANCA (show FANCA Antibodies) and FANCG are the major Fanconi anemia (show PALB2 Antibodies) genes in the Korean population.
Areca nut extracts-induced miR (show MLXIP Antibodies)-23a was correlated with a reduced FANCG expression and DSB repair, which might contribute to ANE-associated human malignancies.
sites of interaction of FANCG with ERCC1 (show ERCC1 Antibodies), which is different from the region of ERCC1 (show ERCC1 Antibodies) that binds to XPF (show ERCC4 Antibodies)
Study of the molecular evolution of FA genes using database search methods such as PSI-BLAST suggested that FANCG may contain a known domain, and that this protein is a member of the family of tetratricopeptide repeat-containing proteins.
There is remarkably lage sequence variation in FANCG gene mutations and polymorphisms across ethnic and racial backgrounds found in the International Fanconi Anemia (show PALB2 Antibodies) Registry they include IVS8-2A>G, IVS11+1G>c, 1794_1803del10, and IVS3+1G>C.
FANCG was able to mediate interaction between FANCA (show FANCA Antibodies) and FANCF (show FANCF Antibodies), as well as between monomers of FANCA (show FANCA Antibodies)
Hematopoietic stem cells of Fancg-/- mice Impaired functionality and homing.
null mutations in Fanca (show FANCA Antibodies) or Fancg are fully epistatic
the FA pathway (FancG) is not involved in regulating the outcome of SHM (show CNTNAP1 Antibodies) in mammals and it appears dispensable for class switch recombination
Data show that Fancd2 (show FANCD2 Antibodies)(-/-) mice displayed a higher magnitude of chromosomal breakage and micronucleus formation than the wild-type or Fancg(-/-) mice.
Double-mutant Fancc (show FANCC Antibodies)(-/-);Fancg(-/-) mice develop spontaneous hematologic sequelae including bone marrow failure, acute myeloid leukemia (show BCL11A Antibodies), myelodysplasia and complex random chromosomal abnormalities that the single-mutant mice do not.
Mice deficient in Fancg were not anemic, but showed hypogonadism, impaired fertility, and hypersensitivity to mitomycin C
FANCG is required for efficient homologous recombination-mediated repair of at least some types of DNA double-strand breaks
Fancg deeficient mouse cells display normal telomere length, normal telomerase activity, and normal chromosome end-capping
a deletion mutation in the FANCG gene (c.637_643delTACCGCC) was present in 82% of Fanconi anemia (show PALB2 Antibodies) patients in the black populations of Southern Africa
Ataxia telangiectasia mutated (show ATM Antibodies) and Fanconi anemia (show PALB2 Antibodies) genes function in parallel and compensatory roles to maintain genomic integrity and cell viability.
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G.
Fanconi anemia complementation group G variant 2
, DNA repair protein XRCC9
, Fanconi anemia group G protein
, X-ray repair complementing defective repair in Chinese hamster cells 9
, X-ray repair, complementing defective, in Chinese hamster, 9
, Fanconi anemia group G protein homolog