FANCG antibody (AA 1-622)

Catalog No. ABIN560843

There are 3+ publications for this product available. The Mouse Monoclonal anti-FANCG antibody is suitable to detect FANCG in samples from Human. It has been validated for WB, ELISA, IF, IP and RNAi.

Quick Overview for FANCG antibody (AA 1-622) (ABIN560843)

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FANCG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), RNA Interference (RNAi)

Clone: 2C8

Product Details anti-FANCG Antibody

Binding Specificity: AA 1-622

Purpose: Mouse monoclonal antibody raised against a full length recombinant FANCG.

Sequence: MSRQTTSVGS SCLDLWREKN DRLVRQAKVA QNSGLTLRRQ QLAQDALEGL RGLLHSLQGL PAAVPVLPLE LTVTCNFIIL RASLAQGFTE DQAQDIQRSL ERVLETQEQQ GPRLEQGLRE LWDSVLRASC LLPELLSALH RLVGLQAALW LSADRLGDLA LLLETLNGSQ SGASKDLLLL LKTWSPPAEE LDAPLTLQDA QGLKDVLLTA FAYRQGLQEL ITGNPDKALS SLHEAASGLC PRPVLVQVYT ALGSCHRKMG NPQRALLYLV AALKEGSAWG PPLLEASRLY QQLGDTTAEL ESLELLVEAL NVPCSSKAPQ FLIEVELLLP PPDLASPLHC GTQSQTKHIL ASRCLQTGRA GDAAEHYLDL LALLLDSSEP RFSPPPSPPG PCMPEVFLEA AVALIQAGRA QDALTLCEEL LSRTSSLLPK MSRLWEDARK GTKELPYCPL WVSATHLLQG QAWVQLGAQK VAISEFSRCL ELLFRATPEE KEQGAAFNCE QGCKSDAALQ QLRAAALISR GLEWVASGQD TKALQDFLLS VQMCPGNRDT YFHLLQTLKR LDRRDEATAL WWRLEAQTKG SHEDALWSLP LYLESYLSWI RPSDRDAFLE EFRTSLPKSC DL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: FANCG (AAH11623, 1 a.a. ~ 622 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-FANCG antibody (ABIN560843)

Kulkarni, Fortunato: "Stimulation of homology-directed repair at I-SceI-induced DNA breaks during the permissive life cycle of human cytomegalovirus." in: Journal of virology, Vol. 85, Issue 12, pp. 6049-54, (2011) (PubMed).

Tsai, Lin, Chiang, Lee, Lee, Ko: "Areca nut induces miR-23a and inhibits repair of DNA double-strand breaks by targeting FANCG." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 123, Issue 2, pp. 480-90, (2011) (PubMed).

Hinz, Nham, Yamada, Tebbs, Salazar, Hinz, Mohrenweiser, Jones, Thompson: "Four human FANCG polymorphic variants show normal biological function in hamster CHO cells." in: Mutation research, Vol. 602, Issue 1-2, pp. 34-42, (2006) (PubMed).

Target Details for FANCG

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Alternative Name: FANCG

Background: Full Gene Name: Fanconi anemia, complementation group G
Synonyms: FAG,XRCC9

Gene ID: 2189

Pathways: DNA Damage Repair