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anti-Fanconi Anemia Complementation Group M (FANCM) Antibodies

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). Additionally we are shipping FANCM Kits (2) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FANCM 57697 Q8IYD8
FANCM 104806 Q8BGE5
FANCM    
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Top anti-FANCM Antibodies at antibodies-online.com

Showing 10 out of 81 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, WB Immunocytochemistry/Immunofluorescence: FANCM Antibody [ABIN4101314] - FANCM antibody was tested in HeLa cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Western Blot: FANCM Antibody [ABIN4101314] - Detection of FANCM in 293 EBN4 cell lysates using ABIN4101314. 0.025 mL Log in to see 5 to 7 Days
$148.31
Details
Human Goat Un-conjugated ELISA   0.1 mg Log in to see 5 to 7 Days
$317.63
Details
Human Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$446.88
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$419.83
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of HeLa and NCI-H460 cells, using FANCM antibody. Immunofluorescence analysis of A549 cell using FANCM antibody. 100 μL Log in to see 14 Days
$323.13
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Mouse Un-conjugated ICC, IF, IP, WB   0.1 mL Log in to see 5 to 7 Days
$317.63
Details
Human Mouse Alexa Fluor 405 WB   0.1 mL Log in to see 6 to 9 Days
$447.56
Details
Human Mouse Alexa Fluor 700 WB   0.1 mL Log in to see 6 to 9 Days
$447.56
Details
Human Mouse Alexa Fluor 647 WB   0.1 mL Log in to see 6 to 9 Days
$447.56
Details

FANCM Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-FANCM Antibodies

  1. Human Polyclonal FANCM Primary Antibody for ELISA - ABIN4271349 : Barroso, Pita, Arias, Menendez, Zamora, Blanco, Benitez, Ribas: The Fanconi anemia family of genes and its correlation with breast cancer susceptibility and breast cancer features. in Breast cancer research and treatment 2009 (PubMed)

More Antibodies against FANCM Interaction Partners

Human Fanconi Anemia Complementation Group M (FANCM) interaction partners

  1. we provide evidence for the first time showing that the common p.Arg1931* loss-of-function variant in FANCM is a risk factor for familial breast cancer.

  2. FANCM c.5101C>T mutation was not identified in Pakistani triple-negative breast cancer patients

  3. MHF facilitates the processing of multiple types of branched DNAs by the DNA translocase FANCM. MHF complex recognizes branched DNA and stimulates FANCM activity at such a structure to promote genome maintenance.

  4. FANCM is a breast cancer susceptibility gene, mutations in which confer a particularly strong predisposition for triple-negative breast cancer

  5. The MHF complex, which is a heterotetramer that comprises two MHF1 (show APITD1 Antibodies)-MHF2 heterodimers, is remodeled by FANCM to favor recognition of branched DNA over dsDNA.

  6. The FANCM translocase domain lies in proximity to C-terminal domain and binding fork DNA structures stimulate its ATPase (show DNAH8 Antibodies) activity.

  7. The traverse frequency was strongly reduced by inactivation of the translocase and DNA binding activities of the FANCM/MHF complex.

  8. Variations of several key residues and the electrostatic property at the active-site region render a catalytically inactive nuclease (show DCLRE1C Antibodies) domain of FANCM, accounting for the lack of nuclease (show DCLRE1C Antibodies) activity.

  9. Genotoxic stress-induced FANCM phosphorylation is ATR-dependent.

  10. FANCM participates in recombination-independent interstrand crosslink repair by facilitating recruitment of lesion incision activities, which requires its translocase activity

Mouse (Murine) Fanconi Anemia Complementation Group M (FANCM) interaction partners

  1. Fancm(Delta2/Delta2) mice also showed unique features atypical for Fanconi anemia (show PALB2 Antibodies) mice, including underrepresentation of female Fancm(Delta2/Delta2) mice and decreased overall and tumor-free survival.

FANCM Antigen Profile

Protein Summary

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M.

Gene names and symbols associated with FANCM

  • Fanconi anemia, complementation group M (FANCM) antibody
  • fanconi anemia complementation group M (PGTG_17854) antibody
  • Fanconi anemia, complementation group M (Fancm) antibody
  • AI427100 antibody
  • C730036B14Rik antibody
  • D12Ertd364e antibody
  • FAAP250 antibody
  • KIAA1596 antibody

Protein level used designations for FANCM

Fanconi anemia complementation group M , fanconi anemia complementation group M , ATP-dependent RNA helicase FANCM , Fanconi anemia group M protein , fanconi anemia-associated polypeptide of 250 kDa , protein Hef ortholog , Fanconi anemia group M protein homolog

GENE ID SPECIES
513626 Bos taurus
10531976 Puccinia graminis f. sp. tritici CRL 75-36-700-3
57697 Homo sapiens
104806 Mus musculus
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