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anti-Fanconi Anemia Group A Protein (FANCA) Antibodies

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). Additionally we are shipping Fanconi Anemia Group A Protein Proteins (4) and Fanconi Anemia Group A Protein Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FANCA 2175 O15360
FANCA 14087 Q9JL70
FANCA 361435  
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Top anti-Fanconi Anemia Group A Protein Antibodies at antibodies-online.com

Showing 10 out of 102 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from HeLa cells treated with IGF 100... Immunohistochemistry analysis of paraffin-embedded human colon carcino... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Chimpanzee Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human colon carcino... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated ELISA, IHC (p) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Uterus, Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated EIA, IHC (p) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Uterus, Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB FANCA Antibody (Center)  western blot analysis in 293 cell line lysate... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using affinity purified anti-FANCA antibody shows detecti... Western blot using antibodies-online's affinity purified anti-FANCA an... 100 μg Log in to see 2 to 3 Days
$369.00
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained wi... 50 μg Log in to see 8 to 10 Days
$451.00
Details

FANCA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Mouse (Murine) , , ,

Rat (Rattus) , ,

Top referenced anti-Fanconi Anemia Group A Protein Antibodies

  1. Chimpanzee Polyclonal FANCA Primary Antibody for EIA, WB - ABIN401266 : Smogorzewska, Matsuoka, Vinciguerra, McDonald, Hurov, Luo, Ballif, Gygi, Hofmann, DAndrea, Elledge: Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair. in Cell 2007 (PubMed)
    Show all 6 references for ABIN401266

  2. Human Polyclonal FANCA Primary Antibody for WB - ABIN2776933 : Haiman, Hsu, de Bakker, Frasco, Sheng, Van Den Berg, Casagrande, Kolonel, Le Marchand, Hankinson, Han, Dunning, Pooley, Freedman, Hunter, Wu, Stram, Henderson: Comprehensive association testing of common genetic variation in DNA repair pathway genes in relationship with breast cancer risk in multiple populations. in Human molecular genetics 2008 (PubMed)

  3. Human Polyclonal FANCA Primary Antibody for IF, IHC - ABIN1531711 : Ianzano, DApolito, Centra, Savino, Levran, Auerbach, Cleton-Jansen, Doggett, Pronk, Tipping, Gibson, Mathew, Whitmore, Apostolou, Callen, Zelante, Savoia: The genomic organization of the Fanconi anemia group A (FAA) gene. in Genomics 1997 (PubMed)

More Antibodies against Fanconi Anemia Group A Protein Interaction Partners

Human Fanconi Anemia Group A Protein (FANCA) interaction partners

  1. Using human and murine cells defective in FANCD2 (show FANCD2 Antibodies) or FANCA and primary bone marrow cells derived from FANCD2 (show FANCD2 Antibodies) deficient mice, we show that the FA pathway removes R loops and that many DNA breaks accumulated in FA cells are R loop-dependent.

  2. FANCA safeguards interphase and mitosis during hematopoiesis

  3. The I939S point mutation prevented binding to the FAAP20 subunit of the FA core complex, caused SUMOylation at K921, RNF4 (show RNF4 Antibodies)-mediated polyubiquitination and degradation.

  4. A frameshifting mutation and a truncating mutation of FANCA are associated with Fanconi anemia (show PALB2 Antibodies).

  5. Proliferation is compromised in FANCA-deficient pluripotent embryonic stem cells.

  6. FANCA-modulated neddylation pathway involved in CXCR5 (show CXCR5 Antibodies) membrane targeting and cell mobility.

  7. BRCA2 (show BRCA2 Antibodies) rs10492396 (AG vs. GG: adjusted hazard ratio (adjHR)=1.85, 95% confidence interval (CI)=1.16-2.95, P=0.010), rs206118 (CC vs. TT+TC: adjHR=2.44, 95% CI=1.27-4.67, P=0.007), rs3752447 and FANCA rs62068372

  8. Results suggest that the nonsynonymous single nucleotide polymorphism (rs2239359) in the FANCA gene or other causal variations coexisting with the GGGAGG haplotype may increase risk of premature ovarian failure in Korean women.

  9. Human Fanconi anemia complementation group a protein stimulates the 5' flap (show ALOX5AP Antibodies) endonuclease activity of FEN1 (show FEN1 Antibodies).

  10. c.190-256_283 + 1680del2040 dupC mutation in the FANCA gene is a founder mutation in Macedonian Fanconi anemia (show PALB2 Antibodies) patients of Gypsy-like ethnic origin.

Mouse (Murine) Fanconi Anemia Group A Protein (FANCA) interaction partners

  1. FANCA safeguards interphase and mitosis during hematopoiesis

  2. study indicates that Fanca expression during endomitosis is crucial for normal megakaryopoiesis and platelet production.

  3. Data show that Fanconi anemia complementation group A Fanca is required for the induction of transition mutations at A/T residues during somatic hypermutation (SHM (show CNTNAP1 Antibodies)) and immunoglobulin (Ig) class switch recombination (CSR (show SCARA3 Antibodies)).

  4. CD25 (show IL2RA Antibodies)(+)Foxp3 (show FOXP3 Antibodies)(+) Tregs of Fanca(-/-) or Fancd2 (show FANCD2 Antibodies)(-/-) mice were less efficient in suppressing the production of GVHD-associated inflammatory cytokines.

  5. null mutations in Fanca or Fancg (show FANCG Antibodies) are fully epistatic

  6. genetic diversity in FANCA, FANCC (show FANCC Antibodies) and FANCL (show FANCL Antibodies) does not support an association of these genes with cervical cancer susceptibility in the Swedish population.

  7. The results support a model where both FANCA and FANCC (show FANCC Antibodies) are part of a multi-protein nuclear FA complex with identical function in cellular responses to DNA damage and germ cell survival.

  8. To study the in vivo role of the FA group A gene (Fanca), gene-targeting techniques were used to generate Fanca(tm1Hsc) mice in which Fanca exons 1-6 were replaced by a beta (show SUCLA2 Antibodies)-galactosidase (show GLB1 Antibodies) reporter construct.

  9. GnRH (show GNRH1 Antibodies) induced a rapid, transient increase in Fanca mRNA.

  10. Fanca protein as an integral component in the early step of homologous repair of DNA double-strand brearks thereby minimizing the genomic instability.

Fanconi Anemia Group A Protein (FANCA) Antigen Profile

Protein Summary

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia.

Gene names and symbols associated with FANCA

  • Fanconi anemia, complementation group A (FANCA) antibody
  • Fanconi anemia, complementation group A (Fanca) antibody
  • AW208693 antibody
  • FA antibody
  • FA-H antibody
  • FA1 antibody
  • FAA antibody
  • FACA antibody
  • FAH antibody
  • FANCH antibody

Protein level used designations for FANCA

Fanconi anemia group A protein , Fanconi anemia, complementation group H , Fanconi anemia, type 1 , Fanconi anemia group A protein homolog

GENE ID SPECIES
2175 Homo sapiens
454393 Pan troglodytes
14087 Mus musculus
415854 Gallus gallus
361435 Rattus norvegicus
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