FANCA antibody (AA 667-694)

Catalog No. ABIN1538566

This Rabbit Polyclonal antibody specifically detects FANCA in WB. It exhibits reactivity toward Human.

Quick Overview for FANCA antibody (AA 667-694) (ABIN1538566)

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCA antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB23899

Product Details anti-FANCA Antibody

Binding Specificity: AA 667-694

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FANCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 667-694 amino acids from the Central region of human FANCA.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: FANCA Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for FANCA

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Alternative Name: FANCA

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia.

Molecular Weight: 162775

Gene ID: 2175

NCBI Accession: NP_000126, NP_001018122

UniProt: O15360

Pathways: DNA Damage Repair