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anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) Antibodies

FDFT1 encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. Additionally we are shipping FDFT1 Kits (33) and FDFT1 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FDFT1 14137 P53798
FDFT1 29580 Q02769
FDFT1 2222 P37268
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Top anti-FDFT1 Antibodies at antibodies-online.com

Showing 10 out of 99 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB FDFT1 Antibody (C-term)  western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the FDFT1 antibody detected the FDFT1 protein (arrow). Western blot analysis of FDFT1 (arrow) using rabbit polyclonal FDFT1 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FDFT1 gene. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma The anti-FDFT1 Pab (ABIN389051) is used in Western blot to detect FDFT1 in mouse cerebellum tissue lysate. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-FDFT1 Antibody (Center) (ABIN389052) pre-incubated without(lane 1) and with(lane 2) blocking peptide (BP2417b) in A375 cell line lysate. FDFT1(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-FDFT1 Antibody Titration: 2.5ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-FDFT1 mouse monoclonal antibody (ABIN2454970) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FDFT1 (RC201392). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FDFT1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-FDFT1. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, IHC, WB Anti-FDFT1 mouse monoclonal antibody (ABIN2454982) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FDFT1 (RC201392). Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-FDFT1 mouse monoclonal antibody. (ABIN2454982) 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample(30 μg of whole cell lysate) A:A431, 12% SDS PAGE antibody diluted at 1:1500 IHC-P Image Immunohistochemical analysis of paraffin-embedded human liver, using FDFT1, antibody at 1:100 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details

FDFT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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Rat (Rattus) ,


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Top referenced anti-FDFT1 Antibodies

  1. Human Polyclonal FDFT1 Primary Antibody for EIA, IHC (p) - ABIN357711 : Soltis, McMahon, Caplan, Dudas, Chamberlin, Vattay, Dottavio, Rucker, Engstrom, Cornell-Kennon: Expression, purification, and characterization of the human squalene synthase: use of yeast and baculoviral systems. in Archives of biochemistry and biophysics 1995 (PubMed)
    Show all 6 references for ABIN357711

  2. Human Polyclonal FDFT1 Primary Antibody for IHC (p), WB - ABIN389052 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 4 references for ABIN389052

  3. Human Polyclonal FDFT1 Primary Antibody for WB - ABIN658482 : Chalasani, Guo, Loomba, Goodarzi, Haritunians, Kwon, Cui, Taylor, Wilson, Cummings, Chen, Rotter,: Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease. in Gastroenterology 2010 (PubMed)
    Show all 2 references for ABIN658482

More Antibodies against FDFT1 Interaction Partners

Mouse (Murine) Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) interaction partners

  1. This study demonistrated that fdft1 is regulate the neuronal cholesterol synthesis during neurite outgrowth.

  2. Result provides the first in vivo evidence that SS plays a regulatory role in cholesterol metabolism through modulation of HMG-CoA reductase (show HMGCR Antibodies) activity and cholesterol biosynthesis.

  3. VEGF (show VEGFA Antibodies) expression, APOPTOSIS, AND ANGIOGENESIS in squalene synthase -ablated neural stem cells wERE strongly upregulated

Human Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) interaction partners

  1. The minor allele in FDFT1 was associated with advanced fibrosis in the non-steatotic but not in the steatotic subgroup in patients with chronic hepatitis C.

  2. Up-regulation of SQS promotes metastasis of lung cancer by enhancing tumor necrosis factor-alpha receptor (show TNFRSF1A Antibodies) 1 and nuclear factor-kappaB activation and matrix metallopeptidase (show ECEL1 Antibodies) 1 expression.

  3. Several critical residues that are involved in binding of NADPH (show NQO1 Antibodies) have been identified in the active site of squalene synthase.

  4. HCV infection increases FDFT1 protein level but not FDFT1 mRNA level.

  5. ABHD5 (show ABHD5 Antibodies), PGRMC1 (show PGRMC1 Antibodies) and SQS are novel markers for sebaceous carcinoma and can reliably distinguish sebaceous neoplasms from non-sebaceous tumors, specifically BCC with clear cell features.

  6. FDFT1 and its encoded enzyme, squalene synthase, may play an important role in prostate cancer development and its aggressive phenotypes.

  7. CTSB (show CTSB Antibodies) and FDFT1 are excluded as candidates for keratolytic winter erythema

  8. NASH (show SAMSN1 Antibodies) is intimately related to fibrosis progression, the FDFT1 SNP is a good candidate for a link with inflammation and fibrosis.

  9. In multivariate models adjusted for age, body mass index, diabetes, waist/hip ratios, and levels of glycated hemoglobin (show HBB Antibodies), the NAFLD (show TSC2 Antibodies) activity score was associated with the SNP rs2645424 on chromosome 8 in farnesyl diphosphate farnesyl transferase 1 (FDFT1)

  10. Results report the high-resolution x-ray structures of human farnesyl pyrophosphate synthase (show FDPS Antibodies) in complexes with risedronate and zoledronate, two of the leading nitrogen-containing bisphosphonates in clinical use.

FDFT1 Antigen Profile

Protein Summary

This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.

Gene names and symbols associated with FDFT1

  • farnesyl-diphosphate farnesyltransferase 1 (FDFT1) antibody
  • farnesyl-diphosphate farnesyltransferase 1 (fdft1) antibody
  • farnesyl-diphosphate farnesyltransferase 1 (LOC100217567) antibody
  • farnesyl diphosphate farnesyl transferase 1 (Fdft1) antibody
  • farnesyl-diphosphate farnesyltransferase 1 (Fdft1) antibody
  • si:ch73-107c13.2 (si:ch73-107c13.2) antibody
  • DGPT antibody
  • DKFZp459C1712 antibody
  • ERG9 antibody
  • fdft1 antibody
  • SQS antibody
  • SS antibody

Protein level used designations for FDFT1

farnesyl-diphosphate farnesyltransferase 1 , squalene synthase , SS , SQS , Squalene synthetase , FPP:FPP farnesyltransferase , squalene synthase-like , farnesyl-diphosphate farnesyltransferase , squalene synthetase , farnesyl diphosphate farnesyltransferase , presqualene-di-diphosphate synthase

GENE ID SPECIES
696396 Macaca mulatta
740684 Pan troglodytes
100029000 Monodelphis domestica
100173463 Pongo abelii
100216201 Xenopus (Silurana) tropicalis
100479603 Ailuropoda melanoleuca
100560926 Anolis carolinensis
100603333 Nomascus leucogenys
100217567 Taeniopygia guttata
14137 Mus musculus
29580 Rattus norvegicus
422038 Gallus gallus
2222 Homo sapiens
477362 Canis lupus familiaris
100312971 Sus scrofa
281767 Bos taurus
100345480 Oryctolagus cuniculus
100714445 Cavia porcellus
101119109 Ovis aries
571911 Danio rerio
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