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Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. Additionally we are shipping Farnesyltransferase, CAAX Box, alpha Proteins (7) and Farnesyltransferase, CAAX Box, alpha Kits (4) and many more products for this protein.
Showing 10 out of 92 products:
Human Polyclonal FNTA Primary Antibody for IHC (p), WB - ABIN1882083
Wang, Danielson, Li, Shah, Kim, Donahoe: The p21(RAS) farnesyltransferase alpha subunit in TGF-beta and activin signaling. in Science (New York, N.Y.) 1996
Show all 5 references for ABIN1882083
Human Polyclonal FNTA Primary Antibody for EIA, WB - ABIN357717
Zhang, Diehl, Kohl, Gibbs, Giros, Casey, Omer: cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I. in The Journal of biological chemistry 1994
Show all 4 references for ABIN357717
Human Polyclonal FNTA Primary Antibody for WB - ABIN389057
Omer, Kral, Diehl, Prendergast, Powers, Allen, Gibbs, Kohl: Characterization of recombinant human farnesyl-protein transferase: cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases. in Biochemistry 1993
Show all 2 references for ABIN389057
Human Polyclonal FNTA Primary Antibody for WB - ABIN2783402
Veluthakal, Kaur, Goalstone, Kowluru: Dominant-negative alpha-subunit of farnesyl- and geranyltransferase inhibits glucose-stimulated, but not KCl-stimulated, insulin secretion in INS 832/13 cells. in Diabetes 2006
Geranylgeranyltransferase inhibitor-2147 (GGTI (show PGGT1B Antibodies)-2147), an inhibitor of protein prenylation, elicited significant inhibition of glucose-stimulated insulin (show INS Antibodies) secretion from INS (show INS Antibodies) 832/13 islet cells.
FTase, via its tubulin (show TUBB Antibodies)-association, is a critical upstream regulator of HDAC6 (show HDAC6 Antibodies) activity
Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13.
, farnesyl-protein transferase alpha-subunit
, protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
, protein prenyltransferase alpha subunit repeat containing 2
, ras proteins prenyltransferase subunit alpha
, type I protein geranyl-geranyltransferase alpha subunit
, CAAX farnesyltransferase subunit alpha
, type I protein geranyl-geranyltransferase subunit alpha
, Farnesyltransferase, subunit alpha