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Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. Additionally we are shipping FAIM3 Kits (11) and FAIM3 Proteins (10) and many more products for this protein.
Showing 10 out of 65 products:
Human Monoclonal FAIM3 Primary Antibody for ELISA, WB - ABIN563980
Proto-Siqueira, Panepucci, Careta, Lee, Clear, Morris, Owen, Rizzatti, Silva, Falcão, Zago, Gribben: SAGE analysis demonstrates increased expression of TOSO contributing to Fas-mediated resistance in CLL. in Blood 2008
Show all 3 references for ABIN563980
Human Polyclonal FAIM3 Primary Antibody for WB - ABIN2476898
Hitoshi, Lorens, Kitada, Fisher, LaBarge, Ring, Francke, Reed, Kinoshita, Nolan: Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells. in Immunity 1998
Show all 2 references for ABIN2476898
Human Polyclonal FAIM3 Primary Antibody for ELISA, WB - ABIN1003348
Curtin, Cotter: Live and let die: regulatory mechanisms in Fas-mediated apoptosis. in Cellular signalling 2003
Show all 2 references for ABIN1003348
Overexpression of TOSO gene is associated with chronic lymphocytic leukemia.
Toso/FcmuR is an IgM receptor capable of activating signaling molecules and whose expression alone is not inherently antiapoptotic.
Overexpression of TOSO in chronic lymphocytic leukemia is associated with disease progression.
TOSO/FAIM3 may play a role in immune surveillance and contribute to B (show TDO2 Antibodies) cell activation (show BLNK Antibodies)
we demonstrate that the immune specific cell surface molecule Toso exhibits antiapoptotic effects on death receptor signaling by a novel regulatory mechanism involving the adaptor kinase RIP1 (show UQCRFS1 Antibodies)
TOSO is overexpressed and correlated with disease progression in chronic lymphocytic leukemia.
This review focuses on possible functional consequences of Plasmodium falciparum EMP1 protein interaction with the IgM receptor, including interference with immunologic signaling and clearance mechanisms and blocking of specific antibody binding.
These results identify TOSO/FAIM3 as a receptor for IgM
enzymatically modified-LDL-generated foam cells are protected from cell death most likely through the expression of TOSO by a FLIP(L) independent mechanism
demonstrated a 5.6-fold increase of TOSO protein in circulating CLL cells and lymph nodes
Toso has an essential role in the differentiation and maturation of iDCs, a process that is required for the control of persistence-prone virus infection.
these findings suggest that FcmuR plays important roles in the regulation of auto-antibody production, Mott cell formation and the differentiation of MZ B cells into plasma cells in B6.MRL Fas (lpr/lpr (show FAS Antibodies)) mice.
FCMR is required for B cell differentiation and homeostasis, the prevention of autoreactive B cells, and responsiveness to antigenic challenge.
Toso is a unique regulator of inflammatory autoimmune responses with a protective role against experimental autoimmune encephalomyelitis
Toso is a unique regulator of innate immune responses during bacterial infection and septic shock.
These results identify TOSO/FAIM3 as a receptor for IgM (show CD40LG Antibodies)
mTOSO overexpressing primary T lymphocytes are resistant to Fas/Fas (show FAS Antibodies) ligand (show FASL Antibodies)-induced apoptosis.
Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009
Fas apoptotic inhibitory molecule 3
, Fc mu receptor
, IgM Fc receptor
, fas apoptotic inhibitory molecule 3
, immunoglobulin mu Fc receptor
, regulator of Fas-induced apoptosis Toso