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Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. Additionally we are shipping Fatty Acyl CoA Reductase 1 Antibodies (25) and Fatty Acyl CoA Reductase 1 Kits (4) and many more products for this protein.
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A peroxisomal disorder of severe intellectual disability, epilepsy, and cataracts due to fatty acyl-CoA reductase 1 deficiency.
Expression of Far1 increased plasmalogen synthesis in wild-type Chinese hamster ovary cells, strongly suggesting that Far1 is a rate-limiting enzyme for plasmalogen synthesis.
ether lipid biosynthesis in mammalian cells is regulated by a negative feedback mechanism that senses cellular plasmalogen levels and appropriately increases or decreases Far1
fatty alcohol synthesis in mammals is accomplished by two fatty acyl-CoA (show GNPAT Proteins) reductase isozymes that are expressed at high levels in tissues known to synthesize wax monoesters and ether lipids
wax monoester synthesis in mammals involves a two step biosynthetic pathway catalyzed by fatty acyl-CoA reductase and wax synthase enzymes
Data indicate that down-regulation of Arabidopsis FATTY ACYL REDUCTASE1 (FAR1), FAR4, and FAR5, which collectively produce the fatty alcohols found in suberin, reduced their levels by 70% to 80%.
FAR1, FAR4, and FAR5 generate the fatty alcohols found in root, seed coat, and wound-induced leaf tissue.
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
fatty acyl-CoA reductase 1
, male sterility domain containing 2
, male sterility domain-containing protein 2
, putative fatty acyl reductase
, short chain dehydrogenase/reductase family 10E, member 1