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Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) Proteins (FCGR3A)

FCGR3A encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. Additionally we are shipping FCGR3A Antibodies (81) and FCGR3A Kits (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FCGR3A 2214 P08637
FCGR3A    
FCGR3A    
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Top FCGR3A Proteins at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
$385.00
Details
HOST_CHO Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Human His tag,AVI tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Baculovirus infected Insect Cells Human His tag,AVI tag,Biotin 50 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Rat His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_CHO Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

FCGR3A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , , ,
, , , ,
Mouse (Murine)

Rat (Rattus)

Top referenced FCGR3A Proteins

  1. Human FCGR3A Protein expressed in Human Cells - ABIN2002744 : Kim, Huang, Hwang, Jones, Sato, Hunter, Kim-Han, Worth, Indik, Schreiber: Fcgamma receptor transmembrane domains: role in cell surface expression, gamma chain interaction, and phagocytosis. in Blood 2003 (PubMed)
    Show all 6 references for ABIN2002744

  2. Human FCGR3A Protein expressed in CHO Cells - ABIN2002740 : Nimmerjahn, Ravetch: Fcgamma receptors: old friends and new family members. in Immunity 2006 (PubMed)
    Show all 5 references for ABIN2002740

  3. Human FCGR3A Protein expressed in Baculovirus infected Insect Cells - ABIN2002755 : Gessner, Grussenmeyer, Schmidt: Differentially regulated expression of human IgG Fc receptor class III genes. in Immunobiology 1996 (PubMed)
    Show all 5 references for ABIN2002755

  4. Rat (Rattus) FCGR3A Protein expressed in Human Cells - ABIN2009036 : Peltz, Grundy, Lebo, Yssel, Barsh, Moore: Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG. in Proceedings of the National Academy of Sciences of the United States of America 1989 (PubMed)
    Show all 5 references for ABIN2009036

  5. Human FCGR3A Protein expressed in CHO Cells - ABIN2002742 : Nagarajan, Chesla, Cobern, Anderson, Zhu, Selvaraj: Ligand binding and phagocytosis by CD16 (Fc gamma receptor III) isoforms. Phagocytic signaling by associated zeta and gamma subunits in Chinese hamster ovary cells. in The Journal of biological chemistry 1995 (PubMed)
    Show all 5 references for ABIN2002742

  6. Human FCGR3A Protein expressed in HEK-293 Cells - ABIN2181078 : Webster, Kedzierska, Azzam, Paukovics, Wilson, Crowe, Jaworowski: Phagocytosis stimulates mobilization and shedding of intracellular CD16A in human monocytes and macrophages: inhibition by HIV-1 infection. in Journal of leukocyte biology 2006 (PubMed)
    Show all 2 references for ABIN2181078

  7. Human FCGR3A Protein expressed in Escherichia coli (E. coli) - ABIN1098659 : Huizinga, van der Schoot, Jost, Klaassen, Kleijer, von dem Borne, Roos, Tetteroo: The PI-linked receptor FcRIII is released on stimulation of neutrophils. in Nature 1988 (PubMed)
    Show all 2 references for ABIN1098659

  8. Human FCGR3A Protein expressed in Wheat germ - ABIN1353901 : Sakamoto, Ito, Hatanaka, Soni, Mori, Sugimura: Discovery and characterization of a peptide motif that specifically recognizes a non-native conformation of human IgG induced by acidic pH conditions. in The Journal of biological chemistry 2009 (PubMed)

More Proteins for Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) Interaction Partners

Human Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) interaction partners

  1. our method allows determining the CNV status of the FCGR locus, we identified association of CNV in FCGR3B to RA and showed a functional relationship between CNV in the FCGR3A gene and CD16A expression.

  2. KRAS wild chemorefractory metastatic colorectal cancer patients with genotype FF of V158F can benefit from cetuximab based therapy

  3. FcgammaRIIIA/FcgammaRIIA gene polymorphisms and HER-2 (show ERBB2 Proteins) may have a role in antibody-dependent cellular cytotoxicity and clinical response to trastuzumab in breast cancer

  4. PAR-2 (show F2RL1 Proteins) expression is increased on CD14 (show NDUFA2 Proteins)++CD16 (show CD16 Proteins)+ monocytes in the peripheral blood of subjects with severe asthma and may be a biomarker of asthma severity.

  5. This study demonstrated the biological importance of human IgG1-Fc Tyr (show TYR Proteins)-296 for interactions with Fc gamma receptor III-A by protein engineering and X-ray structural analysis.

  6. Data suggest that immune complexes (ICs (show DNAI1 Proteins)) of FCGR3A (show CD16 Proteins)-SYK (show SYK Proteins) play critical role in activation of CD4 (show CD4 Proteins)+ T-cells and thus in modulation of adaptive immunity; such ICs (show DNAI1 Proteins) are present in blood from patients with systemic lupus erythematosus.

  7. therapy with rituximab, cyclophosphamide and fludarabine resulted in a significant reduction in the number of non-classical CD14 (show NDUFA2 Proteins)+CD16 (show CD16 Proteins)++ monocytes and soluble form of CD163 (show CD163 Proteins) but upregulation of membrane-associated monocyte CD163 (show CD163 Proteins)

  8. Data show that gains or losses in copy numbers of Fc gamma receptors FCGR3A (show CD16 Proteins) were less frequent than for FCGR3B (show CD16 Proteins) and FCGR2C.

  9. Specific pro-inflammatory monocyte subpopulations positive for CD16 (show CD16 Proteins) and the co-expressed chemokine receptor (show CCR1 Proteins), CX3CR1 (show CX3CR1 Proteins), are discriminative for chronic kidney disease stage 5 on hemodialysis patients.

  10. we address of monocytes functional status through assessment of the patterns of expression of Fcgamma receptors CD64 (show FCGR1A Proteins), CD32 (show FCGR2B Proteins), CD16 (show CD16 Proteins) and CD180 (show CD180 Proteins) receptor on monocytes from CLL patients and healthy individuals using specific mAbs and flow cytometry.

FCGR3A Protein Profile

Protein Summary

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with FCGR3A

  • Fc fragment of IgG, low affinity IIIa, receptor (CD16a) (FCGR3A)
  • CD16 protein
  • CD16A protein
  • FCG3 protein
  • FCGR3 protein
  • FCGRIII protein
  • FCR-10 protein
  • FCRIII protein
  • FCRIIIA protein
  • IGFR3 protein

Protein level used designations for FCGR3A

CD16a antigen , Fc fragment of IgG, low affinity III, receptor for (CD16) , Fc gamma receptor III-A , Fc-gamma RIII-alpha , Fc-gamma RIIIa , Fc-gamma receptor III-2 (CD 16) , Fc-gamma receptor IIIb (CD16) , FcgammaRIIIA , fc-gamma RIII , igG Fc receptor III-2 , immunoglobulin G Fc receptor III , low affinity immunoglobulin gamma Fc region receptor III-A , neutrophil-specific antigen NA

GENE ID SPECIES
2214 Homo sapiens
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