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Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) Proteins (FCGR3A)

FCGR3A encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. Additionally we are shipping FCGR3A Antibodies (289) and FCGR3A Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FCGR3A 2214 P08637
FCGR3A    
FCGR3A    
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Top FCGR3A Proteins at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag Human FCGR3A / CD16a (F158), His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 98%. Immobilized Yervoy Ipilimumab at 5 μg/mL (100 μl/well) can bind Human FCGR3A / CD16a (F158), His Tag (Cat# CDA-H5220) with a linear range of 0.15-5 μg/mL. 100 μg Log in to see 2 to 3 Days
$385.00
Details
HOST_CHO Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Baculovirus infected Insect Cells Human His tag,AVI tag,Biotin 50 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Rat His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_CHO Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

FCGR3A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , , , ,
, , , ,
Mouse (Murine)

Rat (Rattus)

Top referenced FCGR3A Proteins

  1. Human FCGR3A Protein expressed in Human Cells - ABIN2002744 : Kim, Huang, Hwang, Jones, Sato, Hunter, Kim-Han, Worth, Indik, Schreiber: Fcgamma receptor transmembrane domains: role in cell surface expression, gamma chain interaction, and phagocytosis. in Blood 2003 (PubMed)
    Show all 6 references for ABIN2002744

  2. Human FCGR3A Protein expressed in CHO Cells - ABIN2002740 : Nimmerjahn, Ravetch: Fcgamma receptors: old friends and new family members. in Immunity 2006 (PubMed)
    Show all 5 references for ABIN2002740

  3. Human FCGR3A Protein expressed in Baculovirus infected Insect Cells - ABIN2002755 : Gessner, Grussenmeyer, Schmidt: Differentially regulated expression of human IgG Fc receptor class III genes. in Immunobiology 1996 (PubMed)
    Show all 5 references for ABIN2002755

  4. Rat (Rattus) FCGR3A Protein expressed in Human Cells - ABIN2009036 : Peltz, Grundy, Lebo, Yssel, Barsh, Moore: Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG. in Proceedings of the National Academy of Sciences of the United States of America 1989 (PubMed)
    Show all 5 references for ABIN2009036

  5. Human FCGR3A Protein expressed in CHO Cells - ABIN2002742 : Nagarajan, Chesla, Cobern, Anderson, Zhu, Selvaraj: Ligand binding and phagocytosis by CD16 (Fc gamma receptor III) isoforms. Phagocytic signaling by associated zeta and gamma subunits in Chinese hamster ovary cells. in The Journal of biological chemistry 1995 (PubMed)
    Show all 5 references for ABIN2002742

  6. Human FCGR3A Protein expressed in HEK-293 Cells - ABIN2181078 : Webster, Kedzierska, Azzam, Paukovics, Wilson, Crowe, Jaworowski: Phagocytosis stimulates mobilization and shedding of intracellular CD16A in human monocytes and macrophages: inhibition by HIV-1 infection. in Journal of leukocyte biology 2006 (PubMed)
    Show all 2 references for ABIN2181078

  7. Human FCGR3A Protein expressed in Escherichia coli (E. coli) - ABIN1098659 : Huizinga, van der Schoot, Jost, Klaassen, Kleijer, von dem Borne, Roos, Tetteroo: The PI-linked receptor FcRIII is released on stimulation of neutrophils. in Nature 1988 (PubMed)
    Show all 2 references for ABIN1098659

  8. Human FCGR3A Protein expressed in Wheat germ - ABIN1353901 : Sakamoto, Ito, Hatanaka, Soni, Mori, Sugimura: Discovery and characterization of a peptide motif that specifically recognizes a non-native conformation of human IgG induced by acidic pH conditions. in The Journal of biological chemistry 2009 (PubMed)

More Proteins for Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) Interaction Partners

Human Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) interaction partners

  1. FCGR2A/FCGR3A (show CD16 Proteins)-related immune disorder might contribute to the etiology of Takayasu arteritis.

  2. Studies suggest that the Fc gamma receptor IIIA (FCGR3A) 158 V/F polymorphism can predict the treatment response to rituximab-based chemotherapy in non-Hodgkin lymphoma (NHL) patients.

  3. The incidences of the FCGR3A-158 variants VV, VF, and FF for nine patients with relapse were 0 (0 %), 8 (89 %), and 1 (11 %) compared to 13 (11 %), 61 (52 %), and 44 (37 %) in the 118 patients without relapse.

  4. Lower copy numbers (FCGR3A (show CD16 Proteins) and FCGR3B (show CD16 Proteins) genes confer a risk factor for ankylosing spondylitis susceptibility.

  5. This metaanalysis indicates that polymorphisms in the pathways of immune complex clearance, such as the FcgammaRIIIa, FcgammaRIIIb, and ITGAM (show ITGAM Proteins) genotypes, are potential susceptibility genes for neuropsychiatric systemic lupus erythematosus.

  6. Data suggest a mechanism for the increased affinity of GASDALIE Fc for Fc receptor (show FCGRT Proteins) FcgammaRIIIa.

  7. Single-nucleotide polymorphisms of FCGR3A gene is associated with bloodstream infections After Liver Transplantation.

  8. These results suggest that the structure and expression of the CD16 (show CD16 Proteins) molecule differs among FcgammaRIIIa-V158F genotypes, and the FcgammaRIIIa-V158F polymorphism may be represent a haplotype with other SNPs in regulatory regions in Japanese subjects.

  9. FCGR3A (show CD16 Proteins) and FCGR2A (show FCGR2A Proteins) SNPs do not confer differential responsiveness to rituximab.

  10. our method allows determining the CNV status of the FCGR locus, we identified association of CNV in FCGR3B to RA and showed a functional relationship between CNV in the FCGR3A gene and CD16A expression.

FCGR3A Protein Profile

Protein Summary

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with FCGR3A

  • Fc fragment of IgG, low affinity IIIa, receptor (CD16a) (FCGR3A)
  • CD16 protein
  • CD16A protein
  • FCG3 protein
  • FCGR3 protein
  • FCGRIII protein
  • FCR-10 protein
  • FCRIII protein
  • FCRIIIA protein
  • IGFR3 protein

Protein level used designations for FCGR3A

CD16a antigen , Fc fragment of IgG, low affinity III, receptor for (CD16) , Fc gamma receptor III-A , Fc-gamma RIII-alpha , Fc-gamma RIIIa , Fc-gamma receptor III-2 (CD 16) , Fc-gamma receptor IIIb (CD16) , FcgammaRIIIA , fc-gamma RIII , igG Fc receptor III-2 , immunoglobulin G Fc receptor III , low affinity immunoglobulin gamma Fc region receptor III-A , neutrophil-specific antigen NA

GENE ID SPECIES
2214 Homo sapiens
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