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FCGR3A encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. Additionally we are shipping FCGR3A Antibodies (296) and FCGR3A Kits (14) and many more products for this protein.
Showing 10 out of 25 products:
Human FCGR3A Protein expressed in CHO Cells - ABIN2002740
Kim, Huang, Hwang, Jones, Sato, Hunter, Kim-Han, Worth, Indik, Schreiber: Fcgamma receptor transmembrane domains: role in cell surface expression, gamma chain interaction, and phagocytosis. in Blood 2003
Show all 5 references for ABIN2002740
Human FCGR3A Protein expressed in Baculovirus infected Insect Cells - ABIN2002755
Nimmerjahn, Ravetch: Fcgamma receptors: old friends and new family members. in Immunity 2006
Show all 5 references for ABIN2002755
Rat (Rattus) FCGR3A Protein expressed in Human Cells - ABIN2009036
Gessner, Grussenmeyer, Schmidt: Differentially regulated expression of human IgG Fc receptor class III genes. in Immunobiology 1996
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Human FCGR3A Protein expressed in Human Cells - ABIN2002746
Peltz, Grundy, Lebo, Yssel, Barsh, Moore: Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG. in Proceedings of the National Academy of Sciences of the United States of America 1989
Show all 5 references for ABIN2002746
Human FCGR3A Protein expressed in CHO Cells - ABIN2002742
Nagarajan, Chesla, Cobern, Anderson, Zhu, Selvaraj: Ligand binding and phagocytosis by CD16 (Fc gamma receptor III) isoforms. Phagocytic signaling by associated zeta and gamma subunits in Chinese hamster ovary cells. in The Journal of biological chemistry 1995
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Human FCGR3A Protein expressed in Escherichia coli (E. coli) - ABIN1098659
Huizinga, van der Schoot, Jost, Klaassen, Kleijer, von dem Borne, Roos, Tetteroo: The PI-linked receptor FcRIII is released on stimulation of neutrophils. in Nature 1988
Show all 2 references for ABIN1098659
Human FCGR3A Protein expressed in HEK-293 Cells - ABIN2181078
Webster, Kedzierska, Azzam, Paukovics, Wilson, Crowe, Jaworowski: Phagocytosis stimulates mobilization and shedding of intracellular CD16A in human monocytes and macrophages: inhibition by HIV-1 infection. in Journal of leukocyte biology 2006
Show all 2 references for ABIN2181078
Human FCGR3A Protein expressed in Wheat germ - ABIN1353901
Sakamoto, Ito, Hatanaka, Soni, Mori, Sugimura: Discovery and characterization of a peptide motif that specifically recognizes a non-native conformation of human IgG induced by acidic pH conditions. in The Journal of biological chemistry 2009
expression of FcgammaR was not different between immune thrombocytopenia (ITP (show ITPA Proteins)) and controls; the FCGR3A (show CD16 Proteins) (158V/F) polymorphism, known to increase the affinity of FcgammaRIII (show CD16 Proteins) to IgG, was over-represented in ITP (show ITPA Proteins) patients
Increased fraction of CD16 (show CD16 Proteins)(high) CD62L (show SELL Proteins)(dim) neutrophils was shown to correlate with an increased survival rate.
Trastuzumab acidic variants had lesser binding to oncogene (show RAB1A Proteins) protein HER-2 (HER2 (show ERBB2 Proteins)) in comparison to the basic variants, and both acidic and basic variant showed no significant changes in their binding to soluble CD16a receptors.
FCGR3A expression is significantly upregulated in human masticatory mucosa during wound healing
Our findings indicate that CD16 (show CD16 Proteins) 158F>V polymorphism may contribute to the increased risk of Idiopathic Thrombocytopenic Purpura, whereas CD32 (show FCGR2B Proteins) 131H>R polymorphism may not be an important risk factor for Idiopathic Thrombocytopenic Purpura.
this study shows that genetic polymorphisms located within an enhancer FCGR3A influence NK cell-mediated antibody-dependent cellular cytotoxicity
Anti-platelet drugs exert an immunomodulatory action by counteracting CD14 (show NDUFA2 Proteins)(high)CD16 (show CD16 Proteins)(+) monocyte increase under pro-inflammatory conditions, with this effect being dependent on the amplitude of P-selectin (show SELP Proteins) reduction.
analysis of natural killer cell markers in renal transplantation that have roles in acute rejection reveals that CD56 and CD57 are increased in the interstitial compartment in donor-specific antibody (DSA)-negative biopsies from patients with acute antibody-mediated rejection without C4d, and CD16 is increased in the glomerular compartment in DSA-positive biopsies
FCGR2A/FCGR3A (show CD16 Proteins)-related immune disorder might contribute to the etiology of Takayasu arteritis.
Studies suggest that the Fc gamma receptor IIIA (FCGR3A) 158 V/F polymorphism can predict the treatment response to rituximab-based chemotherapy in non-Hodgkin lymphoma (NHL) patients.
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, Fc fragment of IgG, low affinity III, receptor for (CD16)
, Fc gamma receptor III-A
, Fc-gamma RIII-alpha
, Fc-gamma RIIIa
, Fc-gamma receptor III-2 (CD 16)
, Fc-gamma receptor IIIb (CD16)
, fc-gamma RIII
, igG Fc receptor III-2
, immunoglobulin G Fc receptor III
, low affinity immunoglobulin gamma Fc region receptor III-A
, neutrophil-specific antigen NA