Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) Proteins (FCGR3A)

FCGR3A encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. Additionally we are shipping FCGR3A Antibodies (316) and FCGR3A Kits (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FCGR3A 2214 P08637
FCGR3A 304966  
FCGR3A    
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Top FCGR3A Proteins at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 15 to 18 Days
$694.00
Details
HOST_Escherichia coli (E. coli) Rat His tag,GST tag 100 μg Log in to see 15 to 18 Days
$720.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_HEK-293 Cells Human His tag Human FCGR3A / CD16a (F158), His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 98%. Immobilized Yervoy Ipilimumab at 5 μg/mL (100 μl/well) can bind Human FCGR3A / CD16a (F158), His Tag (Cat# CDA-H5220) with a linear range of 0.15-5 μg/mL. 100 μg Log in to see 2 to 3 Days
$385.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
$544.00
Details
HOST_CHO Cells Human His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_Human Cells Human AVI tag,His tag 100 μg Log in to see 20 to 21 Days
$437.80
Details
HOST_Human Cells Rat His tag 100 μg Log in to see 20 to 21 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$319.00
Details
HOST_CHO Cells Human His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details

FCGR3A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , , ,
, , , , ,
Rat (Rattus) ,
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Mouse (Murine) ,
,

Top referenced FCGR3A Proteins

  1. Human FCGR3A Protein expressed in Human Cells - ABIN2002744 : Kim, Huang, Hwang, Jones, Sato, Hunter, Kim-Han, Worth, Indik, Schreiber: Fcgamma receptor transmembrane domains: role in cell surface expression, gamma chain interaction, and phagocytosis. in Blood 2003 (PubMed)
    Show all 6 references for 2002744

  2. Human FCGR3A Protein expressed in Human Cells - ABIN2002748 : Nimmerjahn, Ravetch: Fcgamma receptors: old friends and new family members. in Immunity 2006 (PubMed)
    Show all 5 references for 2002748

  3. Rat (Rattus) FCGR3A Protein expressed in Human Cells - ABIN2009036 : Gessner, Grussenmeyer, Schmidt: Differentially regulated expression of human IgG Fc receptor class III genes. in Immunobiology 1996 (PubMed)
    Show all 5 references for 2009036

  4. Human FCGR3A Protein expressed in CHO Cells - ABIN2002742 : Peltz, Grundy, Lebo, Yssel, Barsh, Moore: Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG. in Proceedings of the National Academy of Sciences of the United States of America 1989 (PubMed)
    Show all 5 references for 2002742

  5. Human FCGR3A Protein expressed in CHO Cells - ABIN2002740 : Nagarajan, Chesla, Cobern, Anderson, Zhu, Selvaraj: Ligand binding and phagocytosis by CD16 (Fc gamma receptor III) isoforms. Phagocytic signaling by associated zeta and gamma subunits in Chinese hamster ovary cells. in The Journal of biological chemistry 1995 (PubMed)
    Show all 5 references for 2002740

  6. Human FCGR3A Protein expressed in HEK-293 Cells - ABIN2181078 : Webster, Kedzierska, Azzam, Paukovics, Wilson, Crowe, Jaworowski: Phagocytosis stimulates mobilization and shedding of intracellular CD16A in human monocytes and macrophages: inhibition by HIV-1 infection. in Journal of leukocyte biology 2006 (PubMed)
    Show all 2 references for 2181078

  7. Human FCGR3A Protein expressed in Escherichia coli (E. coli) - ABIN1098659 : Huizinga, van der Schoot, Jost, Klaassen, Kleijer, von dem Borne, Roos, Tetteroo: The PI-linked receptor FcRIII is released on stimulation of neutrophils. in Nature 1988 (PubMed)
    Show all 2 references for 1098659

More Proteins for Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) Interaction Partners

Human Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) interaction partners

  1. These data suggest a role for FcgammaRIIIa-pSyk cosignaling in modulating NA-TLR responses in human CD4 (show CD4 Proteins)(+) T cells by affecting the amounts and cellular distribution. These events are important for understanding of autoimmune pathology.

  2. This study demonstrated that no association between FCGR3A polymorphisms in Guillain-Barre Syndrome in a Brazilian population.

  3. Intermediate CD14 (show NDUFA2 Proteins)++CD16 (show CD16 Proteins)+monocytes might be closely related to the pathogenesis of atrial fibrillation and reflect functional remodelling of the left atrium.

  4. FCGR3A (show CD16 Proteins) V and FCGR2A (show FCGR2A Proteins) R allele carriers show better responsiveness to anti-TNF-alpha (show TNF Proteins) therapy--{REVIEW}

  5. Single nucleotide polymorphisms (SNPs) rs2099684 in IgG receptors FCGR2A/FCGR3A (show CD16 Proteins) can be considered a genetic risk factor for Takayasu arteritis (TA) in the Chinese Han population.

  6. used a combination of NMR and 1 mus (show TRPV6 Proteins) all-atom computational simulations to identify unexpected contacts between the N45 N-glycan and CD16A polypeptide residues

  7. We conclude that FCGR3A (show CD16 Proteins) CNVs are a major risk factor for female sarcoidosis and FCGR3B (show CD16 Proteins) CNVs may also affect the development of sarcoidosis.

  8. FcgammaRIIIa V allele-restricted pathological complete response benefit from neoadjuvant trastuzumab plus lapatinib in HER2 (show ERBB2 Proteins)+ breast cancer.

  9. CD16+ cells were significantly more frequent among Natural Killer (NK) cells negative for the inhibitory KIR (iKIR) KIR2DL1, KIR2DL3, and KIR3DL1 than those positive for any one of these iKIR to the exclusion of the others, making iKIR+ NK cells poorer antibody dependent cellular cytotoxicity effectors than iKIR- NK cells.

  10. The association of CD16a-inducible NK cell-selective transcripts CD160 (show CD160 Proteins) and XCL1 (show XCL1 Proteins) with kidney biopsies with antibody-mediated rejection provides evidence for NK cell CD16a activation in AMR (show GPR182 Proteins).

FCGR3A Protein Profile

Protein Summary

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with FCGR3A

  • Fc fragment of IgG, low affinity IIIa, receptor (CD16a) (FCGR3A)
  • Fc fragment of IgG, low affinity IIIa, receptor (Fcgr3a)
  • CD16 protein
  • CD16A protein
  • FCG3 protein
  • FCGR3 protein
  • Fcgr4 protein
  • FCGRIII protein
  • FCR-10 protein
  • FCRIII protein
  • FCRIIIA protein
  • IGFR3 protein

Protein level used designations for FCGR3A

CD16a antigen , Fc fragment of IgG, low affinity III, receptor for (CD16) , Fc gamma receptor III-A , Fc-gamma RIII-alpha , Fc-gamma RIIIa , Fc-gamma receptor III-2 (CD 16) , Fc-gamma receptor IIIb (CD16) , FcgammaRIIIA , fc-gamma RIII , igG Fc receptor III-2 , immunoglobulin G Fc receptor III , low affinity immunoglobulin gamma Fc region receptor III-A , neutrophil-specific antigen NA , Fc fragment of IgG intermediate affinity IV receptor , Fc fragment of IgG, low affinity IIIa, receptor for (CD16) , transmembrane receptor FcgammaRIII-X

GENE ID SPECIES
2214 Homo sapiens
304966 Rattus norvegicus
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