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The protein encoded by FCGR3B is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). Additionally we are shipping FCGR3B Antibodies (126) and FCGR3B Kits (16) and many more products for this protein.
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Human FCGR3B Protein expressed in Human Cells - ABIN2003765
Middelhoven, van Buul, Kleijer, Roos, Hordijk: Actin polymerization induces shedding of FcgammaRIIIb (CD16) from human neutrophils. in Biochemical and biophysical research communications 1999
Show all 3 Pubmed References
Gene copy number variation (CNV) of the PKLR (show PKLR Proteins), FCGR2A (show FCGR2A Proteins), FCGR2C, and FCGR3 (show CD16 Proteins) genes is associated with malaria severity, and our results provide evidence for a role of CNV in host responses to malaria.
Association between Fc gamma Receptor (show FCGR1A Proteins) IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya.
We conclude that FCGR3A (show CD16 Proteins) CNVs are a major risk factor for female sarcoidosis and FCGR3B (show CD16 Proteins) CNVs may also affect the development of sarcoidosis.
CD16 and CD35 are important for neutrophil internalization of M. tuberculosis, whereas HIV-1 infection adversely affects opsonophagocytosis.
There was no aberration in FCGR3B (show CD16 Proteins) allele/genotype frequencies in sarcoidosis patients compared to controls.
Results showed that susceptibility to systemic lupus erythematosus was associated with the FCGR3B (show CD16 Proteins)*01 allele, as well as with the FCGR3B (show CD16 Proteins)*01/*01 and FCGR3B (show CD16 Proteins)*01/*02 genotypes.
Lower copy numbers (=3) of FCGR3A (show CD16 Proteins) and FCGR3B (show CD16 Proteins) genes confer a risk factor for ankylosing spondylitis susceptibility.
This metaanalysis indicates that polymorphisms in the pathways of immune complex clearance, such as the FcgammaRIIIa, FcgammaRIIIb, and ITGAM (show ITGAM Proteins) genotypes, are potential susceptibility genes for neuropsychiatric systemic lupus erythematosus.
our method allows determining the CNV status of the FCGR locus, we identified association of CNV in FCGR3B to RA and showed a functional relationship between CNV in the FCGR3A gene and CD16A expression.
Fc-gamma receptor (show FCGR1A Proteins) polymorphisms differentially influence susceptibility to systemic lupus erythematosus and lupus nephritis.
The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1.
Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
, Fc-gamma receptor IIIb (CD 16)
, fc-gamma RIII
, fc-gamma RIII-beta
, fc-gamma RIIIb
, igG Fc receptor III-1
, low affinity immunoglobulin gamma Fc region receptor III-B